Browsing by Title Artículos de revistas

Now showing items 1680-1699 of 2801

    • Mutational landscape and actionable target rates on advanced stage refractory cancer patients: a multicenter ... 
      Córdova Delgado, Miguel Angel; Pinto, Mauricio P.; Regonesi, Carlos; Cereceda, Luis; Reyes, José Miguel; Itriago, Laura; Majlis, Alejandro; Rodríguez, Pablo; Fassler, André; Mahave, Mauricio; León, María Elisa; Gallardo, Jorge; Rodríguez Z., María Paz; Berkovits, Alejandro; Manque, Patricio; Ríos, Juvenal A.; García Bloj, Benjamín; Garrido, Marcelo (MDPI, 2022)
      Major advances in sequencing technologies and targeted therapies have accelerated the incorporation of oncology into the era of precision medicine and "biomarker-driven" treatments. However, the impact of this approach on ...
    • Mutations in mitochondrial aldehyde dehydrogenase (ALDH2) change cofactor affinity and segregate with ... 
      Sapag, Amalia; Tampier de Jong, Lutske; Prieto, A.; Quintanilla González, María Elena; Moncada, C.; Israel Jacard, Yedy (LIPPINCOTT WILLIAMS & WILKINS, 2003-08)
      Genetic factors influence alcohol consumption and alcoholism. A number of groups have bred alcohol drinker and non drinker rat strains, but genetic determinants remain unknown. The University of Chile rat lines UChA (low ...
    • Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding ... 
      Gonzàlez Gronow, Mario; Fiedler Temer, Jenny; Farías Gómez, Cristian; Wang, Fang; Ray, Rupa; Ferrell, Paul D.; Pizzo, Salvatore V. (Elsevier, 2017)
      Myelin basic protein (MBP) is a key component of myelin, the specialized lipid membrane that encases the axons of all neurons. Both plasminogen (Pg) and tissue-type plasminogen activator (t-PA) bind to MBP with high ...
    • N-pool in volcanic ash-derived soils in Chile and its changes in deforested sites 
      Borie B., Gilda; Peirano V., Pedro; Zunino Venegas, Hugo; Aguilera S., S. María (PERGAMON-ELSEVIER SCIENCE LTD, 2002-08)
      Changes in N-distribution patterns in volcanic-ash of Chile after deforestation of a primary forest were measured. There is a clear tendency towards the depletion of N linked to high molecular weight fractions (humin, humic ...
    • N-pool in volcanic ash-derived soils in Chile and its changes in deforested sites (vol 34, pg 1201, 2002) 
      Borie B., Gilda; Peirano V., Pedro; Zunino Venegas, Hugo; Aguilera S., S. María (PERGAMON-ELSEVIER SCIENCE LTD, 2003-01)
      Correction.
    • NaCl soaking treatment for improving the quality of french-fried potatoes 
      Bunger Timmermann, Andrea; Moyano, P. C.; Rioseco, V. (ELSEVIER SCIENCE BV, 2003)
      Potato strips were soaked in 3, 5 or 7% NaCl solutions (25 degreesC) previous to frying, to study the effect on oil uptake. Sensory responses indicated the best texture and lowest oil uptake at 3% NaCl solution for 50 min. ...
    • NADPH oxidase activity: Spectrophotometric determination of superoxide using pyrogallol red 
      Cortés-Ríos, J.; Torres, M. J.; Campos-Bustamante, M. P.; Romero-Parra, J.; Letelier, M. E.; Pessoa-Mahana, D.; Chung, H.; Faúndez, M. (Academic Press Inc., 2017)
      © 2017 Elsevier Inc.A simple and fast spectrophotometric methodology able to quantify superoxide released by NADPH oxidase from differentiated promyelocytic leukaemia (HL-60) cells using pyrogallol red is described.The ...
    • Nanoantioxidant–Based silica particles as flavonoid carrier for drug delivery applications 
      Arriagada, Francisco; Gunther Sapunar, Germán; Morales Valenzuela, Javier (MDPI, 2020)
      Nanosystems used in pharmaceutical formulations have shown promising results in enhancing the administration of drugs of difficult formulations. In particular, porous silica nanoparticles have demonstrated excellent ...
    • Nanodecoration of single crystals of 5,11,17,23-tetra-tert-butyl-25,27- bis(cyanomethoxy)-26,28-dihydroxy ... 
      Moris, S.; Silva, N.; Saitz, C.; Jara, P.; Chornik, B. (Sociedad Chilena de Quimica, 2017)
      © 2017 Sociedad Chilena de Quimica. All rights reserved. Single crystals of 1,3-bis(cyanomethoxy)calix[4]arene (1) were grown from Chloroform/Methanol mixture and these were nanodecorated with colloidal gold nanoparticles ...
    • Nanomedicine and nanotoxicology: the pros and cons for neurodegeneration and brain cancer 
      Catalán Figueroa, Johanna; Palma Florez, Sujey; Alvarez, Gonzalo; Fritz, Hans F.; ara, Miguel O.; Morales, Javier O. (Future Medicine Ltd., 2016)
      Current strategies for brain diseases are mostly symptomatic and noncurative. Nanotechnology has the potential to facilitate the transport of drugs across the blood-brain barrier and to enhance their pharmacokinetic ...
    • Nanoparticle-mediated local and remote manipulation of protein aggregation 
      Kogan Bocian, Marcelo; Bastus, Neus G.; Amigo, Roger; Grillo-Bosch, Dolors; Araya, Eyleen; Turiel, Antonio; Labarta, Amilcar; Giralt, Ernest; Puntes, Víctor F. (AMER CHEMICAL SOC, 2006-01)
      The local heat delivered by metallic nanoparticles selectively attached to their target can be used as a molecular surgery to safely remove toxic and clogging aggregates. We apply this principle to protein aggregates, in ...
    • Nanoparticles as potential novel therapies for urinary tract infections 
      Sánchez, Sofía V.; Navarro Martínez, Nicolás Matías; Catalán Figueroa, Johanna; Morales Montecinos, Javier Octavio (Frontiers Media, 2021)
      Urinary tract infection (UTI) is one of the most common reasons for antibiotic treatment. Nevertheless, uropathogens are steadily becoming resistant to currently available therapies. In this context, nanotechnology emerges ...
    • Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: Evolution toward ... 
      Bejarano, Julian; Navarro Márquez, Mario F.; Morales Zavala, Francisco; Morales, Javier O.; García Carvajal, Ivonne; Araya Fuentes, Eyleen; Flores, Yvo; Verdejo, Hugo E.; Castro, Pablo F.; Lavandero González, Sergio; Kogan Bocian, Marcelo (Ivyspring International Publisher, 2018)
      © Ivyspring International Publisher. Cardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying ...
    • Nanoparticles for the Treatment of Wounds 
      Oyarzún Ampuero, Felipe; Vidal, Alejandra; Concha, Miguel; Morales Montecinos, Javier; Orellana, Sandra; Moreno Villoslada, Ignacio (Bentham, 2015)
      The treatment of skin wounds represents an important research area due to the important physiological and aesthetic role of this tissue. During the last years, nanoparticles have emerged as important platforms to treat ...
    • Nanostructured interfaces containing MWCNT and nitro aromatics: a new tool to determine Nimesulide 
      Moscoso, R.; Álvarez Lueje, Alejandro; Squella Serrano, Juan (Elsevier, 2020)
      A novel type of multiwalled carbon nanotube-modified glassy carbon electrode with an entrapped nimesulide drug was constructed. The new electrode surface was characterized by scanning electrochemical microscopy and scanning ...
    • Naphthoxazole-Based Singlet Oxygen Fluorescent Probes 
      Ruiz González, Rubén; Zanocco, Renzo P.; Gidi, Yasser; Zanocco Loyola, Antonio; Nonell, Santi; Lemp Miranda, Else (The American Society of Photobiology, 2013)
      In this study, we report the synthesis and photochemical behavior of a new family of photoactive compounds to assess its potential as singlet oxygen (1O2) probes. The candidate dyads are composed by a 1O2 trap plus a ...
    • Native and chemically modified porin channels from Salmonella typhi Ty2 in planar lipid bilayers. 
      Labarca, Pedro; Lobos, S.; Calderón, Inés; Mora, Guido C. (Elsevier Science Publisher B. V., 1986)
      Native porins from Salmonella typhi Ty2 outer membrane, and porins alkylated with pyridoxal phosphate (Plp) were studied in planar lipid bilayers. The conductance of bilayers exposed to native or chemically modified porins ...
    • Native and invasive taxa on the Pacific coast of South America: Impacts on aquaculture, traceability and ... 
      Larraín Barth, María Angélica; Zbawicka, Malgorzata; Araneda Tolosa, Cristian; Gardner, Jonathan P. A.; Wenne, Roman (Wiley, 2017)
      Gaining new knowledge of the native distributions of species (phylogeography) is more and more difficult in a world affected by anthropogenic disturbance, in particular by species translocations. ...
    • Natural history of chagasic cardiopathy in Chile. Follow-up of 71 cases after 4 years 
      Apt Baruch, Werner; Arribada,; Cabrera,; Sandoval, (1983)
      As part of study of Chagasic cardiopathy in Chile we report a follow-up study of 100 cardiopathic patients from two endemic areas who had been diagnosed 4 years earlier during an epidemiological and clinical survey. The ...
    • Natural silicate-TiO2 hybrids for photocatalytic oxidation of formaldehyde in gas phase 
      Portela, R.; Jansson, I.; Suárez, S.; Villarroel, M.; Sánchez, B.; Avila, P. (Elsevier B.V., 2017)
      © 2016 Elsevier B.V. Structured hybrid materials based on the combination adsorbent-photocatalyst with optimal mechanical resistance and reduced cost, are prepared by extrusion using four different natural silicates with ...