Browsing by Subject "IL-10"

Now showing items 1-5 of 5

    • A synthetic peptide homologous to IL-10 functional domain induces monocyte differentiation to TGF-β+ ... 
      López, Mercedes N.; Pesce Reyes, Bárbara; Kurte, Mónica; Pérez Núñez, Claudio; Segal, Gabriela; Roa, Johanna; Aguillón Gutiérrez, Juan Carlos; Mendoza Naranjo, Ariadna; Gesser, Borbala; Larsen, Christian; Villablanca, Andrea; Choudhury, Aniruddha; Kiessling, Rolf; Salazar Onfray, Flavio (2011)
      We have previously demonstrated that IT9302, a nonameric peptide homologous to the C-terminal domain of human IL-10, mimics several effects of the cytokine including down-regulation of the antigen presentation machinery ...
    • Immunosuppressive Mechanisms of Regulatory B Cells 
      Catalán Martina, Diego Francisco; Mansilla, Miguel Andrés; Ferrier Espósito, Ashley Andrés; Soto, Lilian; Oleinika, Kristine; Aguillón Gutiérrez, Juan Carlos; Aravena, Octavio (Frontiers Media, 2021)
      Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing immune responses and reestablishing immune ...
    • Pure platelet-rich plasma and supernatant of calcium-activated P-PRP induce different phenotypes of human ... 
      Escobar, Gisselle; Escobar Álvarez, Alejandro; Ascui, Gabriel; Tempio, Fabián I.; Ortiz, María C.; Pérez Núñez, Claudio; López, Mercedes N. (Future Medicine, 2018)
      Aim: This study aimed to evaluate the effect of two platelet preparations used in the clinic, pure platelet-rich plasma (P-PRP) and the supernatant of calcium-activated P-PRP (S-PRP), on the phenotype of human macrophages. ...
    • Systemic sclerosis patients present alterations in the expression of molecules involved in B-cell regulation 
      Soto, Lilian; Ferrier, Ashley; Aravena Madariaga, Octavio; Fonseca, Elianet; Berendsen, Jorge; Biere, Andrea; Bueno, Daniel; Ramos, Verónica; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (Frontiers Media, 2015)
      The activation threshold of B cells is tightly regulated by an array of inhibitory and activator receptors in such a way that disturbances in their expression can lead to the appearance of autoimmunity. The aim of this ...
    • TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic ... 
      Aravena, Octavio; Ferrier, Ashley; Menon, Madhvi; Mauri, Claudia; Aguillón Gutiérrez, Juan Carlos; Soto, Lilian; Catalán Martina, Diego (BioMed Central Ltd., 2017)
      © 2017 The Author(s). Background: Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by excessive production of extracellular matrix by fibroblasts on skin and internal organs. Although Th2 cells have ...