Browsing by Subject "Survivin"

Now showing items 1-7 of 7

    • CK2 functionally interacts with AKT/PKB to promote the β-catenin- dependent expression of survivin and ... 
      Ponce, Daniela P.; Yefi, Roger; Cabello, Pablo; Maturana, Jose L.; Niechi, Ignacio; Silva, Eduardo; Galindo, Mario; Antonelli, Marcelo; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo; Tapia, Julio C. (2011)
      β-Catenin is crucial in the canonical Wnt signaling pathway. This pathway is up-regulated by CK2 which is associated with an enhanced expression of the antiapoptotic protein survivin, although the underlying molecular ...
    • Intradermal DNA electroporation induces survivin-specific CTLs, suppresses angiogenesis and confers protection ... 
      Lladser, Álvaro; Ljungberg, Karl; Tufvesson, Helena; Tazzari, Marcella; Roos, Anna Karin; Quest, Andrew F. G.; Kiessling, Rolf (2010)
      Survivin is an intracellular tumor-associated antigen that is broadly expressed in a large variety of tumors and also in tumor associated endothelial cells but mostly absent in differentiated tissues. Naked DNA vaccines ...
    • Intradermal DNA electroporation induces survivin-speciWc CTLs, suppresses angiogenesis and confers protection ... 
      Lladser, Álvaro; Ljungberg, Karl; Tufvesson, Helena; Tazzari, Marcella; Roos, Anna-Karin; Quest, Andrew F. G.; Kiessling, Rolf (Springer-Verlag, 2010)
      Survivin is an intracellular tumor-associated antigen that is broadly expressed in a large variety of tumors and also in tumor associated endothelial cells but mostly absent in diVerentiated tissues. Naked DNA ...
    • Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer 
      Cerda-Opazo, Paulina; Valenzuela Valderrama, Manuel; Wichmann, Ignacio; Rodríguez, Andrés; Contreras Reyes, Daniel Alberto; Fernández, Elmer A.; Carrasco Aviño, Gonzalo; Corvalán, Alejandro H.; Quest, Andrew F. G. (Impact Journals LLC, 2018)
      © Cerda-Opazo et al. BACKGROUND: The objective of the study was to determine the relationship between Survivin and Reprimo transcript/protein expression levels, and gastric cancer outcome. METHODS: In silico correlations ...
    • Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells 
      Garrido Palma, Maritza; Salvatierra, Renato; Valenzuela Valderrama, Manuel; Vallejos, Christopher; Bruneau, Nicole; Hernández, Andrea; Vega Blanco, María Margarita; Selman Abuchaibe, Alberto; Geoffery Quest, Andrew; Romero Osses, Carmen (MDPI, 2020)
      Epithelial ovarian cancer (EOC) is a lethal gynaecological neoplasm characterized by rapid growth and angiogenesis. Nerve growth factor (NGF) and its high affinity receptor tropomyosin receptor kinase A (TRKA) contribute ...
    • Naked DNA immunization as an approach to target the generic tumor antigen survivin induces humoral and ... 
      Lladser, Álvaro; Párraga, Mario; Quevedo, Licarallén; Molina, Maria Carmen; Silva, Soledad; Ferreira, Arturo; Billetta, Rosario; Quest, Andrew F. G. (Elsevier GmbH, 2006)
      Survivin, a 16.5 kDa tumor associated antigen, is the smallest member of the inhibitor of apoptosis family that is abundantly expressed during development but essentially absent in normal adult tissues. Interestingly, ...
    • Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent ... 
      Fernández, Jaime G.; Rodríguez, Diego A.; Valenzuela, Manuel; Calderon, Claudia; Urzúa, Ulises; Munroe, David; Rosas, Carlos; Lemus, David; Díaz, Natalia; Wright, Mathew C.; Leyton Campos, Lisette; Tapia, Julio C.; Quest, Andrew F. G. (BioMed Central Ltd., 2014)
      © 2014 Fernández et al.; licensee BioMed Central Ltd.Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an ...