Now showing items 1-2 of 2

    • The effects of immunomodulation by macrophage subsets on osteogenesis in vitro 

      Loi, Florence; Córdova Jara, Luis; Zhang, Ruth; Pajarinen, Jukka; Lin, Tzu-hua; Goodman, Stuart B.; Yao, Zhenyu (BioMed Central, 2016)
      Background: Bone formation and remodeling are influenced by the inflammatory state of the local microenvironment. In this regard, macrophages are postulated to play a crucial role in modulating osteogenesis. However, the ...
    • NF-kappa B decoy oligodeoxynucleotide mitigates wear particle-associated bone loss in the murine continuous infusion model 

      Lin, Tzu-hua; Pajarinen, Jukka; Sato, Taishi; Loi, Florence; Fan, Changchun; Córdova Jara, Luis; Nabeshima, Akira; Gibon, Emmanuel; Zhang, Ruth; Yao, Zhenyu; Goodman, Stuart (Elsevier, 2016)
      Total joint replacement is a cost-effective surgical procedure for patients with end-stage arthritis. Wear particle-induced chronic inflammation is associated with the development of periprosthetic osteolysis. Modulation ...