Now showing items 331-350 of 854

    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Mericq, Verónica; Pereira Scalabrino, Ana; Santos, José Luis; Horvath, Steve; Shepherd, John; Michels, Karin B. (Taylor & Francis, 2018)
      Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a ...
    • Fats 
      Mena, Patricia; Uauy Dagach-Imbarack, Ricardo (Karger AG, 2015)
    • Castaño Moreno, Erika; Castillo, Valeska; Peñailillo, Reyna; Llanos Silva, Miguel; Valenzuela Báez, Rodrigo; Ronco Macchiavello, Ana (Elsevier, 2020)
      Micronutrients (folates and vitamin B12) and long chain polyunsaturated fatty acids (LC-PUFAs) are linked through the one carbon cycle. We studied the effects of pre and postnatal high FA/low B12 diets (HFLB12) on hepatic ...
    • Rincón Cervera, Miguel Ángel; Galleguillos Fernández, Raúl; González Barriga, Barriga; Valenzuela Báez, Rodrigo; Speisky Cosoy, Hernán; Fuentes, Jocelyn; Valenzuela, Alfonso (Wiley, 2020)
    • Godler, David E.; Ling, Ling; Gamage, Dinusha; Baker, Emma K.; Bui, Minh; Field, Michael J.; Rogers, Carolyn; Butler, Merlin G.; Murgia, Alessandra; Leonardi, Emanuela; Polli, Roberta; Schwartz, Charles E.; Skinner, Cindy D.; Alliende Rodríguez, Maria Angelica; Santa María Vásquez, Lorena Ivette; Pitt, James; Greaves, Ronda; Francis, David; Oertel, Ralph; Wang, Min; Simons, Cas; Amor, David J. (Asociación Médica Amer, 2021)
      IMPORTANCIA Las pruebas de detección del síndrome de Angelman (AS), el síndrome de Prader-Willi (PWS) y el síndrome de duplicación del cromosoma 15 (Dup15q) en recién nacidos pueden beneficiar el diagnóstico y el tratamiento ...
    • Fasano, A.; Araya, M.; Bhatnagar, S.; Cameron, D.; Catassi, C.; Dirks, M.; Mearin, M. L.; Ortigosa, L.; Phillips, A. (LIPPINCOTT WILLIAMS & WILKINS, 2008-08)
    • Medenica, Sanja; Spoltore, María Elena; Ormazábal Leiva, Paulina Fernanda; Marina, Ljiljana V.; Sojatv, Antoan Stefan; Faggiano, Antongiulio; Gnessi, Lucio; Mazzilli, Rossella; Watanabe, Mikiko (Wiley, 2022)
      Obesity is an epidemic that has led to a rise in the incidence of many comorbidities: among others, reduced fertility is often under-evaluated in clinical practice. The mechanisms underlying the link between reduced fertility ...
    • Mueller, Natalie; Garmendia, María Luisa; Reyes, Marcela; Corvalán Aguilar, Camila; Pereira, Ana; Uauy Dagach-Imbarack, Ricardo (Elsevier, 2018)
      Aims: We aimed to assess whether female offspring birth weight (BW) is associated with anthropometric and metabolic outcomes in Chilean mothers at 10-years postpartum. Methods: We assessed data from 396 Chilean ...
    • Núñez, Héctor; Ruiz, Samuel; Soto Moyano, Rubén; Navarrete, Mario; Valladares Boasi, Luis; White Ortiz, Allan; Pérez, Hernán (ELSEVIER IRELAND LTD, 2008-12-19)
      Prenatal undernutrition induces a variety of cardiovascular alterations inmammalswhenadults, including hypertension and hypercortisolism, which are thought to be caused by decreased glucocorticoid feedback control of the ...
    • Jorquera Ramírez, Carolina; Romero Ormazábal, Jaime (Frontiers Media, 2017)
      The intestinal microbiota is involved in a wide range of biological processes that benefit the host, including providing nutrition and modulating the immune system. Fine flounder (Paralichthys adspersus) is a flatfish of ...
    • Villasante, Alejandro; Ramírez Álvarez, Carolina; Catalán, Natalia; Romero Ormazábal, Jaime (Japanese Society of Microbial Ecology, 2017)
      The aim of the present study was to identify major bacteria associated with the swim bladder in the rainbow trout, Oncorhynchus mykiss. We extracted DNA from the swim bladder and gut contents in order to perform a temporal ...
    • Rojas, Rodrigo; Miranda, Claudio D.; Santander, Javier; Romero Ormazábal, Jaime (2016)
      The VPAP30 strain was isolated as the highly predominant bacteria from an episode of massive larval mortality occurring in a commercial culture of the Chilean scallop Argopecten purpuratus. The main aims of this study were, ...
    • Parra, Alicia de la; García, María Ignacia; Hamilton, Valerie; Arias Pefaur, Carolina; Cabello Andrade, Juan Francisco; Cornejo Espinoza, Verónica (Elsevier, 2017)
      There is a consensus on the importance of early and life-long treatment for PKU patients. Still, differences existon target blood phenylalanine (Phe) concentrations for children with PKU in different countries and ...
    • Santa María Vásquez, Lorena; Aliaga Vera, Solange; Faúndes Gómez, Víctor; Morales Roldán, Paulina; Pugin Aguayo, Ángela; Curotto Liotta, Bianca; Soto Reyes, Paula; Peña, María Ignacia; Salas Aliaga, Isabel; Alliende Rodríguez, María Angélica (Cambridge University Press, 2016)
      Fragile X syndrome (FXS) is the most common form of inherited intellectual disability (ID) and co-morbid autism. It is caused by an amplification of the CGG repeat (>200), which is known as the full mutation, within the ...
    • Baker, Emma K.; Arpone, Marta; Kraan, Claudine; Bui, Minh; Rogers, Carolyn; Field, Michael; Bretherton, Lesley; Ling, Ling; Ure, Alexandra; Cohen, Jonathan; Hunter, Matthew F.; Santa María Vásquez, Lorena; Faúndes Gómez, Víctor; Curotto, Bianca; Morales, Paulina; Trigo, César; Salas, Isabel; Alliende Rodríguez, Angélica; Amor, David J.; Godler, David E. (Nature, 2020)
      Fragile X syndrome (FXS) is caused by a hypermethylated full mutation (FM) expansion with >= 200 CGG repeats, and a decrease in FMR1 mRNA and its protein. However, incomplete silencing from FM alleles has been associated ...
    • Angel, Bárbara; Lera Marques, Lydia; Sánchez Reyes, Hugo; Oyarzún, Amaya; Albala Brevis, Cecilia (Elsevier, 2016)
      Introduction: FokI polymorphismhas been associatedwith obesity and type 2 diabetes (T2D) in somepopulations. Objective: To investigate the frequencies of a genetic polymorphismof Vitamin D receptor (FokI) inpatients with ...
    • Brito, Alex; Mujica Coopman, María; Olivares Grohnert, Manuel; López de Romaña, Daniel; Cori, Héctor; Allen, Lindsay H. (SAGE Publications Inc., 2015)
      Background: The current magnitude of folate and vitamin B-12 deficiency in Latin America and the Caribbean is uncertain. Objective: To summarize data on plasma or serum vitamin B-12 and folate concentrations in Latin ...
    • Rodríguez, Juan M.; Miranda, Dante; Bunout Barnett, Daniel; Ronco Macchiavello, Ana María; Maza Cave, María Pía de la; Hirsch Birn, Sandra (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2015)
      Folic acid (FA) consumption at high levels has been associated with colon cancer risk. Several mechanisms have been proposed to explain this association. The Notch signal pathway has been implicated in the regulation of ...
    • Castillo L., Cecilia; Tur, Josep A.; Uauy Dagach-Imbarack, Ricardo (SOC MEDICA SANTIAGO, 2012-02)
      An increased folate intake may be benefi cial in defi cient populations. However, in women with adequate levels it may not deliver additional benefi ts while it may increase the risk for some forms of cancer. A systematic ...
    • Hertrampf, Eva; Cortés, Fanny (INT LIFE SCIENCES INST NORTH AMERICA, 2004-06)
      Neural tube defects (open spina bifida, anencephaly, and encephalocele) represent the first congenital malformations to be preventable through public health measures such as supplementation and/or food fortification with ...