| Author | dc.contributor.author | Núñez Vergara, Luis | es_CL |
| Author | dc.contributor.author | Salazar González, Ricardo Andrés | es_CL |
| Author | dc.contributor.author | Navarrete Encina, Patricio | es_CL |
| Author | dc.contributor.author | Camargo Grandón, Rodrigo | es_CL |
| Author | dc.contributor.author | Yáñez Soto, Claudia | |
| Author | dc.contributor.author | Squella Serrano, Juan | es_CL |
| Admission date | dc.date.accessioned | 2008-08-29T17:56:43Z | |
| Available date | dc.date.available | 2008-08-29T17:56:43Z | |
| Publication date | dc.date.issued | 2007 | |
| Cita de ítem | dc.identifier.citation | JOURNAL OF THE ELECTROCHEMICAL SOCIETY 154(2):F25-F30 | en |
| Identifier | dc.identifier.issn | 0013-4651 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/120483 | |
| Abstract | dc.description.abstract | A study of the electrolytic oxidation of three new C-4 nitrofuryl 1,4-dihydropyridines in nonaqueous aprotic medium is presented. Controlled-potential electrolysis (CPE) in dimethylformamide +0.1 M tetrabutyl-ammonium hexafluorophosphate (TBAPF(6)) was followed by UV-visible spectroscopy, high-performance liquid chromatography (HPLC)-photodiode array (PDA), and gas chromatography-Mossbauer spectroscopy (GC-MS) chromatography, and electron spin resonance and electrochemical techniques. Carbon-centered radical intermediates produced in the electrochemical oxidation of C-4 nitrofuryl substituted 1,4dihydropyridines were trapped with N-benzylidene-tert-butylamine-N-oxide (PBN) and their splitting constants were calculated. The neutral pyridine derivatives were identified by GC-MS techniques as final oxidation products. HPLC-PDA and GC-MS chromatographic techniques were used to follow the time-course of CPE of both parent 1,4-DHP derivatives and their respective oxidation products. Also, an overall oxidation mechanism of C-4 nitrofuryl-1,4-DHP derivatives is presented. | en |
| Lenguage | dc.language.iso | en | en |
| Publisher | dc.publisher | ELECTROCHEMICAL SOC | en |
| Keywords | dc.subject | HANTZSCH 1,4-DIHYDROPYRIDINES | en |
| Título | dc.title | Electrolytic oxidation of C4-nitrofuryl 1,4-dihydropyridines in nonaqueous medium | en |
| Document type | dc.type | Artículo de revista | |
