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Authordc.contributor.authorSilva Gallardo, Constanza Paulina 
Authordc.contributor.authorFlores Carrasco, Sergio 
Admission datedc.date.accessioned2015-10-14T15:46:38Z
Available datedc.date.available2015-10-14T15:46:38Z
Publication datedc.date.issued2015
Cita de ítemdc.identifier.citationRev Med Chile 2015; 143: 707-715en_US
Identifierdc.identifier.issn0034-9887
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/134362
General notedc.descriptionArtículo de publicación ISIen_US
Abstractdc.description.abstractBackground: Alleles involved in inefficient (ADH1B2*2 and ALDH2*2) or efficient (SNP6, ADH4 gene) alcohol metabolism may influence the risk of alcoholism. Alcoholism susceptibility has been classified as protector and risk-dependence phenotypes, associated with inefficient and efficient alcohol genetic metabolizing variants, respectively. Aim: To investigate the possible association between genetic protective and risk-dependence variants and alcohol intake patterns. Material and Methods: Saliva DNA samples were obtained and the AUDIT (Alcohol Use Disorders Identification Test) questionnaire was applied to 210 university students aged between 18 and 25 years old. Results: No statistically significant association between protective or risk-dependence genetic variants and alcohol pattern intake was detected. However, new categories of alcohol intake patterns-not included in the AUDIT questionnaire-were identified. Conclusions: No association between the protector and risk-dependence phenotypes and patterns of alcohol consumption was detected in this sample of students.en_US
Lenguagedc.language.isoesen_US
Publisherdc.publisherSociedad Médica de Santiagoen_US
Type of licensedc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Keywordsdc.subjectAlcohol Dehydrogenaseen_US
Keywordsdc.subjectAlcohol Drinkingen_US
Keywordsdc.subjectAldehyde Dehydrogenaseen_US
Keywordsdc.subjectGeneticsen_US
Keywordsdc.subjectPopulationen_US
Keywordsdc.subjectGenetic Variationen_US
Títulodc.titlePatrones de consumo y genotipos determinantes de la tolerancia al alcohol: estudio en estudiantes universitarios de Santiago de Chileen_US
Title in another languagedc.title.alternativeAlcohol consumption patterns and genotypes determining alcohol tolerance in Chilean university studentsen_US
Document typedc.typeArtículo de revistaen_US


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Atribución-NoComercial-SinDerivadas 3.0 Chile
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 Chile