| Abstract | dc.description.abstract | The treatment of skin wounds represents an important research area due to the important
physiological and aesthetic role of this tissue. During the last years, nanoparticles have emerged as
important platforms to treat skin wounds. Silver, gold, and copper nanoparticles, as well as titanium
and zinc oxide nanoparticles, have shown potential therapeutic effects on wound healing. Due to
their specific characteristics, nanoparticles such as nanocapsules, polymersomes, solid lipid
nanoparticles, and polymeric nanocomplexes are ideal vehicles to improve the effect of drugs
(antibiotics, growth factors, etc.) aimed at wound healing. On the other hand, if active excipients are
added during the formulation, such as hyaluronate or chitosan, the nanomedicine could significantly
improve its potential. In addition, the inclusion of nanoparticles in different pharmaceutical materials
may enhance the beneficial effects of the formulations, and allow achieving a better dose control.
This paper aims at reviewing significant findings in the area of nanoparticles and wound treatment.
Among the reviewed topics, we underline formulations comprising inorganic, polymeric, surfactant
self-assembled, and lipid nanosystems. Among the drugs included in the nanoformulations, the
paper refers to antibiotics, natural extracts, proteins, and growth factors, among others. Finally, the
paper also addresses nanoparticles embedded in secondary vehicles (fibers, dressings, hydrogels,
etc.) that could improve their application and/or upgrade the release profile of the active | en_US |
