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Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024

Authordc.contributor.authorFerreccio, Catterina 
Authordc.contributor.authorRoa, Juan Carlos 
Authordc.contributor.authorBambs, Claudia 
Authordc.contributor.authorVives, Alejandra 
Authordc.contributor.authorCorvalán, Alejandro H. 
Authordc.contributor.authorCortés, Sandra 
Authordc.contributor.authorFoerster, Claudia 
Authordc.contributor.authorAcevedo, Johanna 
Authordc.contributor.authorHuidobro, Andrea 
Authordc.contributor.authorPassi, Alvaro 
Authordc.contributor.authorToro, Pablo 
Authordc.contributor.authorCovacevich, Yerko 
Authordc.contributor.authorCruz, Rolando de la 
Authordc.contributor.authorKoshiol, Jill 
Authordc.contributor.authorOlivares, Mauricio 
Authordc.contributor.authorMiquel, Juan Francisco 
Authordc.contributor.authorCruz, Francisco 
Authordc.contributor.authorSilva, Raúl 
Authordc.contributor.authorQuest, Andrew F. G. 
Authordc.contributor.authorKogan Bocian, Marcelo 
Authordc.contributor.authorCastro, Pablo F. 
Authordc.contributor.authorLavandero González, Sergio 
Cita de ítemdc.identifier.citationBMC Public Health (2016) 16:122en_US
Identifierdc.identifier.otherDOI: 10.1186/s12889-015-2454-2
General notedc.descriptionArtículo de publicación ISIen_US
Abstractdc.description.abstractBackground: Maule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina's population is of particular interest because in the last few decades it changed from being undernourished to suffering excess caloric intake, and it currently has the highest national rates of cardiovascular diseases, stomach cancer and gallbladder cancer. Between 2009 and 2011 Molina's poverty rate dropped from 24.1 % to 13.5 % (national average 20.4 %); in this period the county went from insufficient to almost complete basic sanitation. Despite these advances, chemical pollutants in the food and air are increasing. Thus, in Molina risk factors typical of both under-developed and developed countries coexist, generating a unique profile associated with inflammation, oxidative stress and chronic diseases. Methods/Design: MAUCO is the core project of the recently established Advanced Center for Chronic Diseases (ACCDiS), Universidad de Chile & Pontificia Universidad Catolica de Chile. In this study, we are enrolling and following 10,000 adults aged 38 to 74 years over 10 years. All eligible Molina residents will be enrolled. Participants were identified through a household census. Consenting individuals answer an epidemiological survey exploring risk factors (psycho-social, pesticides, diet, alcohol, and physical activity), medical history and physical and cognitive conditions; provide fasting blood, urine, and saliva samples; receive an electrocardiogram, abdominal ultrasound and bio-impedance test; and take a hand-grip strength test. These subjects will be re-interviewed after 2, 5 and 7 years. Active surveillance of health events is in place throughout the regional healthcare system. The MAUCO Bio-Bank will store 30 to 50 aliquots per subject using an NIH/NCI biorepository system for secure and anonymous linkage of samples with data. Discussion: MAUCO's results will help design public health interventions tailored to agricultural populations in Latin America.en_US
Patrocinadordc.description.sponsorshipCONICYT (FONDAP) 15130011en_US
Publisherdc.publisherBioMed Centralen_US
Type of licensedc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
Link to Licensedc.rights.uri*
Keywordsdc.subjectProspective studiesen_US
Keywordsdc.subjectCohort studiesen_US
Keywordsdc.subjectPopulation surveillanceen_US
Keywordsdc.subjectChronic disease/epidemiologyen_US
Keywordsdc.subjectAgricultural workers diseasesen_US
Keywordsdc.subjectCardiovascular diseasesen_US
Títulodc.titleStudy protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024en_US
Document typedc.typeArtículo de revistaen_US

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Atribución-NoComercial-SinDerivadas 3.0 Chile
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 Chile