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Improving GRADE evidence tables part 3: detailed guidance for explanatory footnotes supports creating and understanding GRADE certainty in the evidence judgments

Authordc.contributor.authorSantesso, Nancy 
Authordc.contributor.authorCarrasco Labra, Alonso 
Authordc.contributor.authorLangendam, Miranda 
Authordc.contributor.authorBrignardello Petersen, Romina 
Authordc.contributor.authorMustafa, Reem 
Authordc.contributor.authorHeus, Pauline 
Authordc.contributor.authorLasserson, Toby 
Authordc.contributor.authorOpiyo, Newton 
Authordc.contributor.authorKunnamo, Ilkka 
Authordc.contributor.authorSinclair, David 
Authordc.contributor.authorGarner, Paul 
Authordc.contributor.authorTreweek, Shaun 
Authordc.contributor.authorTovey, David 
Authordc.contributor.authorAkl, Elie 
Authordc.contributor.authorTugwell, Peter 
Authordc.contributor.authorBrozek, Jan 
Authordc.contributor.authorGuyatt, Gordon H. 
Authordc.contributor.authorSchunemann, Holger 
Admission datedc.date.accessioned2016-12-06T18:57:40Z
Available datedc.date.available2016-12-06T18:57:40Z
Publication datedc.date.issued2016
Cita de ítemdc.identifier.citationJournal of Clinical Epidemiology 74 (2016) 28-39es_ES
Identifierdc.identifier.other10.1016/j.jclinepi.2015.12.006
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/141694
Abstractdc.description.abstractBackground: The Grading of Recommendations Assessment, Development and Evaluation (GRADE) is widely used and reliable and accurate for assessing the certainty in the body of health evidence. The GRADE working group has provided detailed guidance for assessing the certainty in the body of evidence in systematic reviews and health technology assessments (HTAs) and how to grade the strength of health recommendations. However, there is limited advice regarding how to maximize transparency of these judgments, in particular through explanatory footnotes or explanations in Summary of Findings tables and Evidence Profiles (GRADE evidence tables). Methods: We conducted this study to define the essential attributes of useful explanations and to develop specific guidance for explanations associated with GRADE evidence tables. We used a sample of explanations according to their complexity, type of judgment involved, and appropriateness from a database of published GRADE evidence tables in Cochrane reviews and World Health Organization guidelines. We used an iterative process and group consensus to determine the attributes and develop guidance. Results: Explanations in GRADE evidence tables should be concise, informative, relevant, easy to understand, and accurate. We provide general and domain-specific guidance to assist authors with achieving these desirable attributes in their explanations associated with GRADE evidence tables. Conclusions: Adhering to the general and GRADE domain-specific guidance should improve the quality of explanations associated with GRADE evidence tables, assist authors of systematic reviews, HTA reports, or guidelines with information that they can use in other parts of their evidence synthesis. This guidance will also support editorial evaluation of evidence syntheses using GRADE and provide a minimum quality standard of judgments across tables. (C) 2016 Elsevier Inc. All rights reservedes_ES
Patrocinadordc.description.sponsorshipGRADE Center at McMaster University Methods Innovation Fund of the Cochrane Collaborationes_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherElsevieres_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Sourcedc.sourceJournal of Clinical Epidemiologyes_ES
Keywordsdc.subjectLevels of evidencees_ES
Keywordsdc.subjectGRADEes_ES
Keywordsdc.subjectSummary of Findings tablees_ES
Keywordsdc.subjectEvidence Profilees_ES
Keywordsdc.subjectExplanationses_ES
Keywordsdc.subjectGuidelineses_ES
Keywordsdc.subjectGRADEproes_ES
Keywordsdc.subjectSystematic reviewses_ES
Títulodc.titleImproving GRADE evidence tables part 3: detailed guidance for explanatory footnotes supports creating and understanding GRADE certainty in the evidence judgmentses_ES
Document typedc.typeArtículo de revistaes_ES
Catalogueruchile.catalogadorapces_ES
Indexationuchile.indexArtículo de publicación ISIes_ES


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile