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Potential use of nanocarriers with pentacyclic triterpenes in cancer treatments

Authordc.contributor.authorValdés Camus, Karina 
Authordc.contributor.authorMorales, Javier 
Authordc.contributor.authorRodríguez, Lennin 
Authordc.contributor.authorGünther Sapunar, Germán 
Admission datedc.date.accessioned2018-03-06T14:41:41Z
Available datedc.date.available2018-03-06T14:41:41Z
Publication datedc.date.issued2016-12
Cita de ítemdc.identifier.citationNanomedicine Volume: 11 Issue: 23es_ES
Identifierdc.identifier.issn1748-6963
Identifierdc.identifier.other10.2217/nnm-2016-0251
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/146702
Abstractdc.description.abstractUrsolic, oleanolic and betulinic acids are representative pentacyclic triterpenoids found in various plants and fruits. Despite having marked antitumor potentials, the very poor water solubility of these triterpenes hinders treatment development. Nanotechnology can enhance solubility, stability, bioavailability and phytochemical delivery, improving the therapeutic efficiency of triterpenes. This review focuses on the formulation, characterization and in vitro/in vivo evaluation of several delivery nanosystems used to enhance the physicochemical properties of ursolic, oleanolic and betulinic acids.es_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherFuture Medicine Ltdes_ES
Sourcedc.sourceNanomedicinees_ES
Keywordsdc.subjectursolic acides_ES
Keywordsdc.subjectoleanolic acides_ES
Keywordsdc.subjectnanotechnologyes_ES
Keywordsdc.subjectnanosystemses_ES
Keywordsdc.subjectnanoparticleses_ES
Keywordsdc.subjectnanoemulsiones_ES
Keywordsdc.subjectnanocarrierses_ES
Keywordsdc.subjectliposomeses_ES
Keywordsdc.subjectbetulinic acides_ES
Keywordsdc.subjectantitumorales_ES
Títulodc.titlePotential use of nanocarriers with pentacyclic triterpenes in cancer treatmentses_ES
Document typedc.typeArtículo de revistaes_ES
Catalogueruchile.catalogadorcrbes_ES
Indexationuchile.indexArtículo de publicación ISIes_ES
Access notedct.AccessRightsSin acceso a texto completoes_ES


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