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Analgesic action of clonixin, nifedipine and morphine using the formalin test

Authordc.contributor.authorBustamante, 
Authordc.contributor.authorMiranda, 
Authordc.contributor.authorPelissier, 
Authordc.contributor.authorPaeile, 
Admission datedc.date.accessioned2018-12-20T15:05:11Z
Available datedc.date.available2018-12-20T15:05:11Z
Publication datedc.date.issued1989
Cita de ítemdc.identifier.citationGeneral Pharmacology, Volumen 20, Issue 3, 2018, Pages 319-322
Identifierdc.identifier.issn03063623
Identifierdc.identifier.other10.1016/0306-3623(89)90266-8
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/157710
Abstractdc.description.abstract1. 1. The analgesic effect of C1X, nifedipine, metamizol, indoprofen and morphine in the pain induced by formalin injection (formalin test) was studied. 2. 2. Attempts to demonstrate tolerance to C1X were unsuccessful. 3. 3. In the analgesic test nifedipine and morphine are approximately 10 times more potent than C1X. 4. 4. The present results suggest that the analgesic action of C1X is not mediated by μ1, δ or κ-opioid receptors and the anti-nociceptive effect of nifedipine may be associated with the blockade of the transmembrane inward movements of calcium. © 1989.
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceGeneral Pharmacology
Keywordsdc.subjectPharmacology
Títulodc.titleAnalgesic action of clonixin, nifedipine and morphine using the formalin test
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile