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Authordc.contributor.authorVargas-Bello-Pérez, Einar 
Authordc.contributor.authorBionaz, Massimo 
Authordc.contributor.authorGarrido Sartore, Macarena 
Authordc.contributor.authorCancino Padilla, Nathaly 
Authordc.contributor.authorMorales, María Sol 
Authordc.contributor.authorRomero Ormazábal, Jaime 
Authordc.contributor.authorLeskinen, Heidi 
Authordc.contributor.authorGarnsworthy, Philip C. 
Authordc.contributor.authorLoor, Juan J. 
Admission datedc.date.accessioned2020-05-06T23:18:01Z
Available datedc.date.available2020-05-06T23:18:01Z
Publication datedc.date.issued2020
Cita de ítemdc.identifier.citationAnimals 2020, 10, 54es_ES
Identifierdc.identifier.other10.3390/ani10010054
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/174478
Abstractdc.description.abstractSimple Summary: The objective of this study was to determine the effects of degree of unsaturation of dietary lipids on lipid-related metabolites and transcription of genes involved in lipid metabolism in subcutaneous adipose tissue (SAT) of mid-lactating dairy cows. The objective was achieved by supplementing dairy cows with soybean oil (high in linoleic acid) or fish oil (high in polyunsaturated fatty acids) for 63 days (nine weeks). Results revealed effects of oil supplement on lipid metabolism but a mild effect on the transcriptome of the adipose tissue. Compared to soybean oil, fish oil had a higher lipogenic effect in SAT. Abstract. The objective of this study was to determine the effect of long-term supplementation of unsaturated oil on lipid metabolism and transcription of genes involved in lipid metabolism in subcutaneous adipose tissue (SAT) of mid-lactating dairy cows. The objective was achieved by supplementing dairy cows with soybean oil (SO; high in linoleic acid) or fish oil (FO; high in EPA and DHA) for 63 days (nine weeks). Cows were fed a control diet with no added lipid, or diets containing SO or FO (n = 5 cows/group). At the onset of the experiment (day 0) and on days 21, 42, and 63 of supplementation, blood and SAT samples were collected from each animal. Oil supplementation increased cholesterol and NEFA in plasma, with a greater effect of SO compared to FO. Concentration of BUN was lower in SO compared to control and FO at the end of the trial. Transcription of few genes was affected by dietary lipids: FABP4 had lowest expression in FO followed by SO and control. ACACA and FASN had higher expression in FO. Transcription of SCAP was higher but expression of INSIG1 was lower in SO. Overall, results revealed that compared to control, SO and FO had lipogenic effect in SAT.es_ES
Patrocinadordc.description.sponsorshipComision Nacional de Investigacion Cientifica y Tecnologica (CONICYT), CONICYT FONDECYT: 1170400es_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherMDPIes_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Sourcedc.sourceAnimalses_ES
Keywordsdc.subjectFat supplementationes_ES
Keywordsdc.subjectTranscriptomices_ES
Keywordsdc.subjectSubcutaneous adipose tissuees_ES
Keywordsdc.subjectLactating cowses_ES
Títulodc.titleEffect of Soybean Oil and Fish Oil on Lipid-Related Transcripts in Subcutaneous Adipose Tissue of Dairy Cowses_ES
Document typedc.typeArtículo de revistaes_ES
dcterms.accessRightsdcterms.accessRightsAcceso Abierto
Catalogueruchile.catalogadorrvhes_ES
Indexationuchile.indexArtículo de publicación ISI
Indexationuchile.indexArtículo de publicación SCOPUS


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile