Browsing by Author "f8035d90-b4a4-4d74-8f03-0e7a8ebf9cf0"

Now showing items 1-3 of 3

    • Analysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary ... 
      Barría, María Inés; González, Angel; Vera Otarola, Jorge; León, Ursula; Vollrath, Valeska; Marsac, Delphine; Monasterio Opazo, Octavio; Pérez-Acle, Tomás; Soza, Alejandro; López-Lastra, Marcelo (2009)
      The HCV internal ribosome entry site (IRES) spans a region of ∼340 nt that encompasses most of the 5′ untranslated region (5′UTR) of the viral mRNA and the first 24-40 nt of the core-coding region. To investigate the ...
    • Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions ... 
      Lagos, Carlos F.; Araya Secchi, Raúl; Thomas, Pablo; Pérez-Acle, Tomás; Tapia, Ricardo A.; Salas, Cristian O. (2012)
      Trypanosoma cruzi glutamate cysteine ligase (TcGCL) is considered a potential drug target to develop novel antichagasic drugs. We have used a variety of computational methods to investigate the interactions between TcGCL ...
    • New approaches for predicting protein retention time in hydrophobic interaction chromatography 
      Lienqueo Contreras, María Elena; Mahn Osses, Andrea; Navarro, Gonzalo; Salgado, J. Cristián; Pérez-Acle, Tomás; Rapaport Zimermann, Iván; Asenjo de Leuze, Juan (JOHN WILEY, 2006-08)
      Hydrophobic interaction chromatography (HIC) is an important technique for the purification of proteins. In this paper, we review three different approaches for predicting protein retention time in HIC, based either on a ...