Browsing by Author "201-0432762"
Now showing items 21-40 of 49
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(Pergamon, 1997-11)Crude and partially purified somatic (S) and excretorysecretory (ES) antigens of Fasciola hepatica were subjected to Western blot analysis in order to identify polypeptides that would enable specitic and sensitive immu ...
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(2007)Using the murine model of type II collagen-induced arthritis (CIA), we studied its evolution over time by histopathological, immunohistochemical and clinical evaluations. The first clinical symptoms appeared 28 days ...
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(2009-02)Background: Periodontitis is an infection with an episodic pattern of tissue-support destruction. During the generation of a primary CD4+ T helper 1 (Th1) response, interferon-gamma (IFN-g) acts as a positive regulator ...
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(American Academy of Periodontology, 2011-10)BACKGROUND: A growing body of evidence suggested that interleukin (IL)-21 enhances the effector phase during T-cell responses. The aim of our study is to determine the levels of IL-21 in periodontal sites from patients ...
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(2016)Cellular therapies, with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation The methodologies ...
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(Sociedad de Biología de Chile, 2005)Longitudinal studies aimed at evaluating patients clinical response to specific therapeutic treatments are frequently summarized in incomplete datasets due to missing data. Multivariate statistical procedures use only ...
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(JOHN LIBBEY EUROTEXT LTD, 2006-06)Crohn's disease (CD) and ulcerative colitis (UC) are multifactorial diseases with a genetic background. Genes related to the innate immune response have been observed to be involved. Polymorphisms of Toll-like receptor 4 ...
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(Sociedad Médica de Santiago, 2003)The fusion of a murine B cell and a myeloma cell generates a hybridoma that produces monoclonal antibody (mAb). These murine mAb induce the HAMA (human anti-mouse antibodies) response. Murine mAb have been modified by ...
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(Sociedad Médica de Santiago, 2005)Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects 0.8% of the world population, it affects the synovial membrane of joints and the clinical presentation encompasses a wide spectrum, ranging from a ...
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(Universidad de Chile, 2008)Las células dendríticas (DCs) cumplen un rol fundamental en la ejecución y regulación de la respuesta inmune. En los últimos años su producción in vitro se ha convertido en una herramienta de gran utilidad en inmunología. ...
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(Sociedad de Periodoncia de Chile., 2010-12)La enfermedad periodontal requiere de un hospedero susceptible para su desarrollo y progresión. Dentro de las características del hospedero se encuentra la respuesta T reguladora, que otorga tolerancia frente a antígenos ...
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(1997)If the H-2 congenic mouse strains A.SW (H-2(s)) and A.CA (H-2(f)), are infected with Trypanosoma cruzi, a 45 kDa protein (Tc45), present in cultured epimastigotes and blood trypomastigotes, is recognized only by the A.SW ...
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(BioMed Central, 2013)Background: Generation of tolerogenic dendritic cells (TolDCs) for therapy is challenging due to its implications for the design of protocols suitable for clinical applications, which means not only using safe products, ...
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(2007)Dendritic cells (DCs) are professional, antigen-presenting cells, which induce and regulate T cell reactivity. DCs are crucial in innate and adaptive immune responses, and are also involved in central and peripheral tolerance ...
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(2007)Dendritic cells (DCs) are professional, antigen-presenting cells, which induce and regulate T cell reactivity. DCs are crucial in innate and adaptive immune responses, and are also involved in central and peripheral tolerance ...
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(Elsevier, 2015)To date, the available options to treat autoimmune diseases such as rheumatoid arthritis (RA) include traditional corticoids and biological drugs, which are not exempt of adverse effects. The development of cellular ...
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(Elsevier, 2017)NKG2D is an activating receptor expressed on NK cells that binds to a variety of ligands, including MICA and MICB. These cell surface glycoproteins are overexpressed under cellular transformation, thus playing an important ...
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(Frontiers Media, 2015)The activation threshold of B cells is tightly regulated by an array of inhibitory and activator receptors in such a way that disturbances in their expression can lead to the appearance of autoimmunity. The aim of this ...
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(Sociedad Médica de Santiago, 2005)The use of biological agents such as etanercept, infliximab, adalimumab and anakinra has been recently approved for the treatment of rheumatoid arthritis. All are effective controlling signs and symptoms and inhibiting ...
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(Springer, 2011)The introduction of antitumor necrosis factor (TNF) agents has improved the outcome for many patients with rheumatoid arthritis (RA). To date, the only replicated genetic predictor of anti-TNF response is the −308 G > ...
