Browsing by Author "647a6824-828c-4848-b4ff-834f8718c3b5"

Now showing items 21-28 of 28

    • Medicinal plants of Chile: Evaluation of their anti-trypanosoma cruzi activity 
      Muñoz, Orlando M.; Maya Arango, Juan; Ferreira, Jorge; Christen, Philippe; San Martín, José; López Muñoz, Rodrigo; Morello Casté, Antonio; Kemmerling Weis, Ulrike (Verlag der Zeitschrift fur Naturforschung, 2013)
      The extracts of several plants of Central Chile exhibited anti-Trypanosoma cruzi trypomastigotes activity. Most active extracts were those obtained from Podanthus ovatifolius, Berberis microphylla, Kageneckia oblonga, and ...
    • Modulation of the response of prostate cancer cell lines to cisplatin treatment using small interfering RNA 
      Parra, Eduardo; Ferreira, Jorge (2013)
      Cisplatin is one of the most effective and widely used chemotherapeutic agents against several types of human cancers. However, the underlying mechanisms of action are not fully understood. We aimed to investigate the ...
    • Overexpression of EGR-1 modulates the activity of NF-κB and AP-1 in prostate carcinoma PC-3 and LNCaP cell lines 
      Parra, Eduardo; Ferreira, Jorge; Ortega, Arnaldo (2011)
      To address elements that might uniquely characterize EGR-1 mediated signaling, the expression of two transcription factors, namely, nuclear factor kappa B (NF-κB) and activator protein-1 (AP-1) were studied. PC-3 and LNCaP ...
    • Roles of Trypanosoma cruzi calreticulin in parasite-host interactions and in tumor growth 
      Ramírez, Galia; Valck Calderón, Carolina Eliana; Aguilar, Lorena; Kemmerling Weis, Ulrike; López Muñoz, Rodrigo; Navarro Cabrera, Gonzalo; Morello Casté, Antonio; Ferreira, Jorge; Maya Arango, Juan; Galanti Garrone, Norbel; Ferreira, Arturo (2012)
      In Latin America, there are about 10-12 million people infected with Trypanosoma cruzi, the agent of Chagas' disease, one of the most important neglected tropical parasitism. Identification of molecular targets, specific ...
    • Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role ... 
      Campos Estrada, Carolina; Liempi, Ana; González Herrera, Fabiola; Lapier, Michel; Kemmerling Weis, Ulrike; Pesce Reyes, Bárbara; Ferreira, Jorge; López Muñoz, Rodrigo; Maya Arango, Juan (Public Library of Science, 2015)
      © 2015 Campos-Estrada et al.Trypanosoma cruzi is the causal agent of Chagas Disease that is endemic in Latin American, afflicting more than ten million people approximately. This disease has two phases, acute and chronic. ...
    • t-butyl-4-hydroxyanisole as an inhibitor of tumor cell respiration 
      Fones, Elizabeth; Amigo, Hannelore; Gallegos, Kimie; Guerrero, Anibal; Ferreira, Jorge (1989)
      The effect of t-butyl-4-hydroxyanisole (BHA), a widely used food antioxidant additive, on the culture growth, oxygen consumption, and redox state of some electron carriers of intact TA3 and 786A ascites tumor cells has ...
    • The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines 
      Parra, Eduardo; Ferreira, Jorge (2010)
      We have examined the effects of a siRNA targeting the Egr-1, alone or in combination with the breast cancer therapeutic camptothecin (Cpt), in suppressing breast cancer cell survival and anchorage-independent growth in the ...
    • The oxygen-binding properties of hemocyanin from the mollusk Concholepas concholepas 
      González, Andrea; Nova, Esteban; Del Campo, Miguel; Manubens, Augusto; Ioannes, Alfredo de; Ferreira, Jorge; Becker, María Inés (Elsevier B.V., 2017)
      © 2017 Elsevier B.V. Hemocyanins have highly conserved copper-containing active sites that bind oxygen. However, structural differences among the hemocyanins of various mollusks may affect their physicochemical properties. ...