Browsing by Author "XX588220"
Now showing items 21-40 of 93
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Moisset, P.; Vaisman, D.; Cintolesi, A.; Urrutia, J.; Rapaport Zimermann, Iván; Andrews Farrow, Bárbara; Asenjo de Leuze, Juan (2012-09)A continuous model of a metabolic network including gene regulation to simulate metabolic fluxes during batch cultivation of yeast Saccharomyces cerevisiae was developed. The metabolic network includes reactions ...
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Peña Álvarez, Jaime Enrique (Universidad de Chile, 2011)La biotecnología ha adquirido un rol fundamental en la industria de producción de biofármacos, la cual ofrece nuevas alternativas para el tratamiento de diversas enfermedades. Entre los más utilizados están los anticuerpos ...
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Lienqueo Contreras, María Elena; Mahn Osses, Andrea; Salgado, J. Cristián; Asenjo de Leuze, Juan (2007)This paper gives a summary of different aspects for predicting protein behaviour in hydrophobic interaction chromatography (HIC). First, a brief description of HIC, hydrophobic interactions, amino acid and protein ...
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Cortés Venegas, Iván Ignacio (Universidad de Chile, 2015)Debido a la creciente demanda energética mundial, junto al agotamiento próximo del petróleo y el aumento de su precio, se haces necesario impulsar alternativas energéticas como los biocombustibles, que pueden aportar en ...
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Design and implementation of a high yield production system for recombinant expression of peptides Rodríguez, Vida; Asenjo de Leuze, Juan; Andrews Farrow, Bárbara (Bio Med Central, 2014)Making peptide pharmaceuticals involves challenging processes where many barriers, which include production and manufacture, need to be overcome. A non common but interesting research area is related to peptides with ...
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Rateb, Mostafa E.; Houssen, Wael E.; Harrison, William T. A.; Deng, Hai; Okoro, Chinyere K.; Asenjo de Leuze, Juan; Andrews Farrow, Bárbara; Bull, Alan T.; Goodfellow, Michael; Ebel, Rainer; Jaspars, Marcel (AMER CHEMICAL SOC, 2011-09)The metabolic profile of Streptomyces sp. strain C34, isolated from the Chilean hyper-arid Atacama Desert soil, is dependent on the culture media used for its growth. The application of an OSMAC approach on this strain ...
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Medina Ortiz, David; Silva Contreras, Sebastián Jesús; Quiroz, Cristofer; Asenjo de Leuze, Juan; Olivera Nappa, Álvaro (Elsevier, 2020)Tremendous advances in different areas of knowledge are producing vast volumes of data, a quantity so large that it has made necessary the development of new computational algorithms. Among the algorithms developed, we ...
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Shene, Carolina; Paredes, Paris; Flores, Liset; Leyton, Allison; Asenjo de Leuze, Juan; Chisti, Yusuf (Wiley, 2020)Production of biomass and lipids in batch cultures of the Antarctic thraustochytridOblongichytriumsp. RT2316-13, is reported. The microorganism proved capable of producing nearly 67% docosahexaenoic acid (DHA) and 15% ...
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Olivera Nappa, Álvaro; Lagomarsino, G.; Andrews Farrow, Bárbara; Asenjo de Leuze, Juan (ELSEVIER, 2004-07-25)An attempt has been made to adopt a different approach to evaluate the effect of a protein's charge on its partitioning behaviour in PEG/salt aqueous two-phase systems (ATPS). This has been done using a computer methodology ...
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Mahn Osses, Andrea; Lienqueo Contreras, María Elena; Asenjo de Leuze, Juan (ELSEVIER, 2004-07-16)The effect of surface hydrophobicity distribution of proteins on retention in hydrophobic interaction chromatography (HIC) was investigated. Average surface hydrophobicity as well as hydrophobic contact area between protein ...
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Sandoval, Gabriela; Andrews Farrow, Bárbara; Asenjo de Leuze, Juan (John Wiley & Sons, 2012-08-21)Differentmathematicalmodels with different degrees of complexity have been proposed to model affinity chromatography. In this work, in particular, a general rate model has been studied that considers axial dispersion, ...
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Enzimas lipolíticas de krill antártico : purificación y caracterización, ¿enzimas adaptadas al frío? Barriga González, Andrés Antonio (Universidad de Chile, 2006)La temperatura es uno de los factores ambientales más importantes para la vida, siendo los ambientes fríos los que presentan la mayor distribución en la biosfera. Diferentes organismos han desarrollado diversas estrategias ...
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Salazar, Oriana; Asenjo de Leuze, Juan (SPRINGER, 2007-07)Cell wall lytic enzymes are valuable tools for the biotechnologist, with many applications in medicine, the food industry, and agriculture, and for recovering of intracellular products from yeast or bacteria. The ...
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Salinas Ayala, Lilian Angélica (Universidad de ChilePrograma Cybertesis, 2008)En esta tesis hemos estudiado dos problemas: el primero consiste en encontrar condiciones mínimas para obtener una cierta clase de recubrimientos del plano discreto mediante cuadrados y el segundo corresponde al estudio ...
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Pezoa Conte, Ricardo Miguel (Universidad de ChileCyberDocs, 2010)
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Rodríguez Gallardo, Vida (Universidad de ChilePrograma Cybertesis, 2007)
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Evolución dirigida mediante mutagénesis por saturación de la xilanasa L de origen marino antártico Romero Núñez, María Patricia (Universidad de Chile, 2012)Las proteínas psicrófilas resultan muy útiles a nivel industrial pues permiten un ahorro de energía por presentar una alta actividad específica a bajas temperaturas en comparación con sus homólogas mesófilas (activas a ...
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Extension of the selection of protein chromatography and the rate model to affinity chromatographyy Sandoval, G.; Shene, C.; Andrews Farrow, Bárbara; Asenjo de Leuze, Juan (John Wiley & Sons, 2010-08-03)The rational selection of optimal protein purification sequences, as well as mathematical models that simulate and allow optimization of chromatographic protein purification processes have been developed for purification ...
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Consuegra Valenzuela, Verónica Angélica (Universidad de Chile, 2014)Las algas se utilizan desde tiempos inmemoriales para consumo humano y extracción de subproductos. Entre los más conocidos estas los ficocoloidales como el alginato, agar y carragenano, de gran valor en la industria ...
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Campodónico, Miguel A.; Andrews Farrow, Bárbara; Asenjo de Leuze, Juan; Palsson, Bernhard O.; Feist, Adam M. (Elsevier, 2014)The production of 75% of the current drug molecules and 35% of all chemicals could be achieved through bioprocessing (Arundel and Sawaya, 2009). To accelerate the transition from a petroleum-based chemical industry to a ...