Browsing by Author "XX590463"

Now showing items 21-32 of 32

    • Phylogenetic Analysis of Hepatitis B Virus Genotype F Complete Genome Sequences From Chilean Patients With ... 
      Venegas Santos, Mauricio; Alvarado Mora, Mónica V.; Villanueva Arancibia, Rodrigo; Rebello Pinho, Joao R.; Carrilho, Flair J.; Locarnini, Stephen; Yuen, Lilly; Brahm Barril, Javier (WILEY-LISS, INC., 2011)
      Molecular epidemiological data concerning the hepatitis B virus (HBV) in Chile are not known completely. Since the HBV genotype F is the most prevalent in the country, the goal of this study was to obtain full HBV ...
    • Polimorfismos cercanos al gen IL28B y su relación con la infección con el virus hepatitis B 
      Venegas Santos, Mauricio; Torres B., Claudio; Brahm Barril, Javier (2012)
      Three top single-nucleotide polymorphisms (rs12979860, rs12980275 and rs8099917) near to IL28B gene have been associated to spontaneous or relate to treatment-induced hepatitis C virus clearence. The role of this ...
    • Prevalence of hepatitis B virus genotypes in chronic carriers in Santiago, Chile 
      Venegas Santos, Mauricio; Muñoz Espinoza, Gabriela; Hurtado Heim, Carmen; Alvarez, Luis; Velasco Rayo, Marta; Villanueva Arancibia, Rodrigo; Brahm Barril, Javier (SPRINGER WIEN, 2008-11)
      The eight genotypes (designated A–H) of hepatitis B virus (HBV) display distinctive geographical distribution worldwide, with genotypes A, D and F frequently detected in South America. To determine the prevalence of ...
    • Re-evaluación de seroprevalencia de virus hepatitis E 
      Covarrubias, Natalia; Hurtado Hein, Carmen; Díaz, Alex; Mezzano, Gabriel; Brahm Barril, Javier; Venegas Santos, Mauricio (Sociedad Chilena de Infectología, 2015)
      Reported seroprevalence of hepatitis E virus (HEV) in developed countries is between 0.3-53%. Published data relies on the assays used and its technical performance. Sensitivity on new available tests has improved, which ...
    • Replication of a chronic hepatitis B virus genotype F1b construct 
      Hernández, Sergio; Jiménez, Gustavo; Alarcón, Valentina; Prieto, Cristian; Muñoz, Francisca; Riquelme, Constanza; Venegas Santos, Mauricio; Brahm Barril, Javier; Loyola, Alejandra; Villanueva, Rodrigo A. (Springer, 2016)
      Genotype F is one of the less-studied genotypes of human hepatitis B virus, although it is widely distributed in regions of Central and South American. Our previous studies have shown that HBV genotype F is prevalent ...
    • Resultados del tratamiento con peginterferón alfa-2a y ribavirina en pacientes con hepatitis crónica C 
      Pizarro, Carolina; Venegas Santos, Mauricio; Hola, Karen; Smok Sahid, Gladys; Brahm Barril, Javier (2011)
      Background: The current treatment recommendation for chronic hepatitis C virus infection is the combination of peginterferon and ribavirin for 24 or 48 weeks, depending on the viral genotype. The aim of the therapy is ...
    • Seroconversion in response to a reinforced primary hepatitis B vaccination in children with cancer ... 
      Villena, Rodolfo; Zubieta, Marcela; Hurtado, Carmen; Salgado, Carmen; Silva, Gladys; Fernández, Jazmine; Villarroel, Milena; Fernández, Marisol; Brahm Barril, Javier; O'Ryan Gallardo, Miguel; Santolaya de Pablo, María Elena (Sociedad Chilena de Pediatria, 2015)
      © 2015 Sociedad Chilena de Pediatría.Introduction: Immune response against vaccine antigens may be impaired in children with cancer. The aim of this study was to evaluate the seroconversion response against hepatitis B ...
    • Síndrome de superposición autoinmune secuencial (hepatitis autoinmune/colangitis esclerosante primaria) y ... 
      Núñez Figueroa, Paulina; Sedano, Rocío; Quera, Rodrigo; Carrasco Avino, Gonzalo; O'Brien, Andrés; Brahm, Javier (Aran Ediciones, 2020)
      La enfermedad inflamatoria intestinal (EII) se relaciona con distintas manifestaciones hepáticas como compromiso extraintestinal; la colangitis esclerosante primaria (CEP) es la más frecuente de ellas. Durante su ...
    • Sobredosis de paracetamol: una nueva forma de suicidio en Chile y el valor de la administracion de N-acetilcisteina 
      Brahm Barril, Javier; Silva, G.; Palma, R. (Sociedad Médica de Santiago, 1992)
      Overdose of paracetamol is associated to varying degrees of hepatic necrosis and may lead to severe hepatic failure. In this paper, we report 2 patients with paracetamol overdose for suicidal purposes who were successfully ...
    • TM6SF2 rs58542926 Polymorphism is not Associated With Risk of Steatosis or Fibrosis in Chilean Patients ... 
      Urzúa Manchego, Álvaro; Mezzano, Gabriel; Brahm Barril, Javier; Poniachik Teller, Jaime; Miranda, Julio; Carreno, Laura; Venegas Santos, Mauricio (Kowsar, 2017)
      Background: The polymorphism rs58542926 C > T (E167K) in the gene of transmembrane 6 superfamily member 2 (TM6SF2) has been identified as a determinant of hepatic steatosis and fibrosis in patients with non-alcoholic fatty ...
    • Variabilidad genética del virus hepatitis B y su significado clínico 
      Venegas Santos, Mauricio; Villanueva Arancibia, Rodrigo; Brahm Barril, Javier (Hospital Clínico Universidad de Chile, 2010)
      The Hepatitis B virus (HBV) is the prototype member of the Hepadnaviridae family, which can cause acute or chronic hepatic illness. The virus has a partially double-stranded DNA genome of 3.2 kb. Molecular variations and ...
    • The viral transactivator HBx protein exhibits a high potential for regulation via phosphorylation through ... 
      Hernández, Sergio; Venegas Santos, Mauricio; Brahm Barril, Javier; Villanueva Arancibia, Rodrigo (2012)
      Background: Hepatitis B virus (HBV) encodes an oncogenic factor, HBx, which is a multifunctional protein that can induce dysfunctional regulation of signaling pathways, transcription, and cell cycle progression, among ...