Browsing by Author "e2c7a69b-1bf4-449c-907e-76a1ceb89ebf"
Now showing items 21-40 of 78
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Shahab, Muhammad; Lippincott, Margaret; Chan, Yee-Ming; Davies, Addie; Merino Osorio, Paulina; Plummer, Lacey; Mericq, Verónica; Seminara, Stephanie (Oxford University Press, 2018)Context: Hypothalamic kisspeptin signaling plays a critical role in the initiation and maintenance of reproductive function. Biallelic mutations in the coding sequence of KISS1R (GPR54) have been identified in patients ...
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Mericq, Verónica; Pereira Scalabrino, Ana; Uauy Dagach-Imbarack, Ricardo; Corvalán Aguilar, Camila (Karger, 2017)Background: Accelerated weight and height gain in infancy have been associated with premature adrenarche. However, the exact tempo of these events remains undefined. Thus, our goal was to assess the relationship between ...
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Kraus, J.; Reyes, M.; Rossel, K.; Iñíguez Vila, Germán; Mericq, Verónica (Karger, 2015)
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Mericq, Verónica; Cassorla Goluboff, Fernando; Salazar, Teresa; Ávila, Alejandra; Iñíguez Vila, Germán; Bowers, Cyril Y.; Merriam, George R. (1998)Stimulation of pituitary GH secretion with administered GHRH can be effective therapy for those GH deficient (GHD) patients whose disorder results from insufficient endogenous GHRH secretion. We have previously shown that ...
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Cassorla Goluboff, Fernando; Mericq, Verónica; Eggers, Martha; Avila, Alejandra; García, Cristian; Fuentes, Ariel; Rose, Susan R.; Cutler, Gordon B. (Endocrine Society, 1997)To study the effect of delaying epiphyseal fusion on the growth of GH- deficient children, we studied 14 pubertal, treatment naive. GH-deficient patients (6 girls and 8 boys) in a prospective, randomized, placebo- controlled ...
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Mericq, Verónica; Gajardo, Héctor; Eggers, Martha; Avila, Alejandra; Cassorla Goluboff, Fernando (Endocrine Society, 2002)The aim of the present study was to assess the impact of treatment with GH with or without LHRH analog (LHRH-A) on bone mineralization of GH-deficient adolescents. We studied 17 pubertal, treatment-naive, GH-deficient ...
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Mericq, Verónica; Medina, Pablo; Bouwman, Carolien; Johnson, M. Cecilia; Godoy, Jorge; López, Teresa; Iñíguez Vila, Germán (2009)Background: Glucocorticoid excess promotes visceral obesity and cardiovascular disease. Ligand availability to the glucocorticoid receptor is controlled by isoforms of 11β-hydroxysteroid dehydrogenase (11β-HSD) which ...
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Gaete, Ximena; López Romero, Patricia Eugenia; Unanue, Nancy; Codner Dujovne, Ethel; Cavada Chacón, Gabriel; Mericq, Verónica (2016)Background: Menarche is the last stage of pubertal development, which coincides, with the completion of longitudinal growth. Our aim was to evaluate, post-menarcheal growth and clinical variables proposed to be associated ...
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Lammoglia, Juan Javier; Mericq, Verónica (2009)Hyperphosphatemic familial tumoral calcinosis (HFTC) is an uncommon disease characterized by periarticular calcifications produced by the deposition of amorphous extraosseous calcifications of hydroxyapatite. It is associated ...
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Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls Binder, Alexandra M.; Corvalán Aguilar, Camila; Mericq, Verónica; Pereira Scalabrino, Ana; Santos, José Luis; Horvath, Steve; Shepherd, John; Michels, Karin B. (Taylor & Francis, 2018)Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a ...
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Iñíguez Vila, Germán; Ong, Ken; Peña, Verónica; Ávila, Alejandra; Dunger, David; Mericq, Verónica (2002)Wide ranges in postnatal weight gain are seen in infants born small for gestational age (SGA); most show some catch-up growth and this may be driven by increased appetite. Ghrelin, the natural ligand of the GH secretagogue ...
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Merino Osorio, Paulina; Cerda, T.; Bollmann, J.; Mericq, Verónica (Karger, 2016)
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Aglony, Marlene; Martínez-Aguayo, Alejandro; Carvajal, Cristian A.; Campino, Carmen; García, Hernán; Bancalari, Rodrigo; Bolte, Lillian; Avalos, Carolina; Loureiro, Carolina; Trejo, Pamela; Brinkmann, Karin; Giadrosich, Vinka; Mericq, Verónica; Rocha, Ana; Avila, Aleja (Lippincott Williams and Wilkins, 2011)Familial hyperaldosteronism type 1 is an autosomal dominant disorder attributed to a chimeric CYP11B1/CYP11B2 gene (CG). Its prevalence and manifestation in the pediatric population has not been established. We aimed to ...
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Busch, Alexander S.; Hagen, Casper P.; Main, Katharina M.; Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Almstrup, Kristian; Mericq, Verónica; Juul, Anders (Oxford Academic, 2017)Context: Although genetic factors play a pivotal role in male pubertal timing, genome-wide association studies have identified only a few loci. Genetic variation of follicle-stimulating hormone (FSH) action affects adult ...
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Iñíguez Vila, Germán; Román, Rossana; Youlton, Ronald; Cassorla Goluboff, Fernando; Mericq, Verónica (2011)Background: Novel molecular insights have suggested that ghrelin may be involved in the pathogenesis of some forms of short stature. Recently, growth hormone secretagogue receptor (GHSR) mutations that segregate with short ...
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Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Merino Osorio, Paulina; Iñíguez Vila, Germán; Mericq, Verónica (Karger, 2017)
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Pereira Scalabrino, Ana; Iñíguez Vila, Germán; Corvalán Aguilar, Camila; Mericq, Verónica (Oxford, 2017)Context: Premature adrenarche (PA) has been associated with increased metabolic risk. Objective: To describe the risk of precocious thelarche (PT; ,8 years), pubarche (PP; girls ,8 years, boys ,9 years), and gonadarche ...
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García, Roberto J.; Martínez Aguayo, Alejandro; Mericq, Verónica (2012)Early referral is the key to the optimal management of growth failure. Evidence shows that there is no universal consensus for endocrinologists on the handling, tracking and monitoring of growth hormone (GH) treatment. The ...
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Eyzaguirre, Francisca; Mericq, Verónica (2009)The prevalence of obesity among children and adolescents is progressively increasing around the world. One of the important consequences of obesity is the development of insulin resistance (IR). This condition has a ...
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Toso, Alberto; Ayala, María José; Brunner, Valentina; Rodríguez, Josefina; Hernández Cárdenas, María Isabel; Urquidi, Cinthya; Mericq, Verónica (Sociedad Médica de Santiago, 2012)Background: The interests that motivate medical students to study this career are diverse and they may change during the seven years of study. In Chile, 22 universities offer medicine and the number of graduated students ...