Now showing items 21-40 of 116

    • Humeres, Claudio; Vivar, Raúl; Boza Fuentes, Pía; Muñoz, Claudia; Bolivar, Samir; Anfossi, Renatto; Osorio, Jose Miguel; Olivares Silva, Francisco Javier; García Nannig, Lorena; Díaz Araya, Guillermo (Academic Press, 2016)
      © 2016 Elsevier Ltd Macrophage polarization plays an essential role in cardiac remodeling after injury, evolving from an initial accumulation of proinflammatory M1 macrophages to a greater balance of anti-inflammatory M2 ...
    • Díaz Araya, Guillermo; Vivar Sánchez, Raúl; Humeres Martínez, Claudio; Boza Fuentes, Pía; Bolívar, S.; Muñoz, C. (Elsevier, 2015)
      Cardiac fibroblasts (CF) not only modulate extracellular matrix (ECM) proteins homeostasis, but also respond to chemical and mechanical signals. CF express a variety of receptors through which they modulate the proliferation/cell ...
    • Castro, Pablo; Mc-Nab, Pablo; Bittner, Alex; Greig, Douglas; Quintana, Juan Carlos; Chiong Lay, Mario; Díaz Araya, Guillermo; Valenzuela, Rodrigo; Vergara, I.; Corbalán, Ramón; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2005-02-01)
      Meeting Abstract
    • Díaz Araya, Guillermo; Marambio, Andrés; Watkins Sepulveda, Juan Guillermo; Castro, Fabiola; Riffo, Andrea; Zúñiga, Roberta; Jans, Jaime; Villanueva, María E. (Baishideng Publishing Group, 2014)
      AIM: To describe the variation that divalent metal transporter 1 (DMT1) shows in patients after Rouxen- Y gastric bypass (RYGB) surgery. METHODS: Prospective and analytical study of DMT1 level at the brush border of ...
    • Rivas Espinosa, Cristopher Fabián (Universidad de Chile, 2013)
      Los fibroblastos cardiacos son las principales células no contráctiles presentes en el miocardio. Su función principal es preservar la estructura y el buen funcionamiento cardiaco, lo cual se realiza a través de la ...
    • Ibacache Figueroa, Mauricio; Sánchez, Gina; Gálvez, Felipe; Pedrozo Cibils, Zully; Humeres Martínez, Claudio; Echevarría, Ghislaine; Duaso, Juan; Hassi, Mario; García Nannig, Lorena; Díaz Araya, Guillermo; Lavandero González, Sergio (ELSEVIER, 2012-04)
      Pharmacological preconditioning limits myocardial infarct size after ischemia/reperfusion. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist used in anesthesia that may have cardioprotective properties against ...
    • Aránguiz Urroz, Pablo Daniel; Soto Muñoz, Dagoberto; Contreras Ferrat, Ariel Eduardo; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Montenegro Obregón, José Joaquín; Venegas Pino, Daniel Esteban; Smolic Smolic, Christian; Ayala Jeria, Pedro Segundo; Thomas, W. G.; Lavandero González, Sergio; Díaz Araya, Guillermo (NATURE PUBLISHING GROUP, 2009-05)
      The Angiotensin II (Ang II) type 1 (AT(1)R) and type 2 (AT(2)R) receptors are increased in the heart following myocardial infarction and dilated cardiomyopathy, yet their contribution at a cellular level to compensation ...
    • Catalán, Mabel; Smolic, Christian; Contreras, Ariel; Ayala, Pedro; Olmedo, Ivonne; Copaja, Miguel; Boza Fuentes, Pía; Vivar, Raúl; Avalos, Yennifer; Lavandero González, Sergio; Velarde, Victoria; Díaz Araya, Guillermo (2012)
      Kinins mediate their cellular effects through B1 (B1R) and B2 (B2R) receptors, and the activation of B2R reduces collagen synthesis in cardiac fibroblasts (CF). However, the question of whether B1R and/or B2R have a role ...
    • Copaja Soto, Miguel; Valenzuela, Rodrigo; Saldaña, Adiela; Ocaranza, María Paz; Jalil Milad, Jorge; Vio, Carlos; Lijnen, Paul; Ordenes, Gamaliel; Vivar Sánchez, Raúl; Lavandero González, Sergio; Díaz Araya, Guillermo (SAGE PUBLICATIONS LTD, 2008-09)
      Introduction. Isoproterenol treatment of Brown Norway Lewis rats (high and low plasma angiotersin-I-converting enzyme activity., respectively) results in similar cardiac hypertrophy but higher cardiac fibrosis in Brown ...
    • Parra Flores, Pablo Ignacio (Universidad de Chile, 2020)
      El infarto agudo de miocardio es una de las principales causas de muerte global y, por lo tanto, una enfermedad que ha sido ampliamente estudiada. En el infarto, una causa que contribuye al daño celular es la reperfusión ...
    • Morales Pezoa, Cristina Alejandra (Universidad de ChileCyberDocs, 2008)
      El cobre es un elemento traza esencial, necesario e indispensable para numerosos e importantes procesos vitales, como metabolismo energético, modulación de la respuesta inmune y neurotransmisión, entre muchos otros. El ...
    • Castro, Pablo; Pérez, Osvaldo; Greig, Douglas; Díaz Araya, Guillermo; Moraga, Francisco; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Padilla, Ivonne; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Lavandero González, Sergio (Sociedad Española de Cardiología, 2004)
      El carvedilol es un antagonista adrenérgico con acción antioxidante y un demostrado beneficio sobre la mortalidad en insuficiencia cardíaca (IC). El objetivo de este estudio es evaluar, en pacientes con insuficiencia ...
    • Miranda, Rodrigo; Castro, Pablo; Verdejo, Hugo; Greig, Douglas; Alcaíno Olivares, Hernán Alejandro; Bustos Contreras, Carlos Andrés; Vukasovic Ramírez, José Luis; Godoy, Iván; Díaz Araya, Guillermo; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2007-03-06)
      Meeting Abstract
    • Castro, Pablo; Pérez, Osvaldo; Greig, Douglas; Díaz Araya, Guillermo; Moraga, Francisco; Chiong Lay, Mario; Troncoso, Rodrigo; Padilla, Ivonne; Vukasovic, Jose L.; Corbalán, Ramón; Lavandero González, Sergio (Ediciones Doyma, S.L., 2004)
      Introduction and objective. Carvedilol is an antioxidant and adrenergic antagonist with demonstrated benefits in terms of mortality from heart failure (HF). The aim of the present study was to evaluate clinical parameters, ...
    • Castro Agüero, Pablo; Pérez, Osvaldo; Greig, Douglas; Díaz Araya, Guillermo; Moraga, Francisco; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Padilla, Ivonne; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Lavandero González, Sergio (EDICIONES DOYMA S/L, 2004-11)
      Introduction and objective. Carvedilol is an antioxidant and adrenergic antagonist with demonstrated benefits in terms of mortality from heart failure (HF). The aim of the present study was to evaluate clinical parameters, ...
    • Castro, Pablo; Mc-Nab, Pablo; Quintana, Juan Carlos; Bittner, Alex; Greig, Douglas; Vergara, Ismael; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Copaja, Miguel; Díaz Araya, Guillermo; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Alcaíno Gálvez, Hernán Alejandro; Lavandero González, Sergio (ELSEVIER SCIENCE BV, 2005-10)
      Background: Our previous studies suggest that the increase in heart rate from rest to peak exercise is reduced in patients with chronic heart failure (CHF) and this is associated with increased oxidative stress, as determined ...
    • Castro, Pablo; Mac Nab, Paul; Quintana, Juan Pablo; Bittner, Alex; Greig, Douglas; Vergara, I.; Vukasovic Ramírez, José Luis; Corbalán, Ramón; Copaja, Miguel; Díaz Araya, Guillermo; Chiong Lay, Mario; Troncoso Cotal, Rodrigo; Alcaíno Olivares, Hernán Alejandro; Lavandero González, Sergio (EXCERPTA MEDICA INC, 2005-07-15)
      Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 ...
    • Castro, Pablo; Díaz Araya, Guillermo; Nettle Danniels, Maurice; Corbalán, Ramón; Pérez, Osvaldo; Nazzal Nazal, Carolina; Larrain, Germán; Lavandero González, Sergio (EXCERPTA MEDICA INC, 2002-01-15)
      It has been reported that patients with congestive heart failure (CHF) have increased breath pentane content, conjugated diene levels, and plasma malondialdehyde (MDA) levels, an indirect marker of lipid peroxidation.(1-3) ...
    • Ocaranza, María Paz; Godoy, Iván; Jalil Milad, Jorge; Varas, Manuel; Collantes, Patricia; Pinto, Melissa; Román, Maritza; Ramírez, Cristián; Copaja, Miguel; Díaz Araya, Guillermo; Castro, Pablo; Lavandero González, Sergio (LIPPINCOTT WILLIAMS & WILKINS, 2006-10)
      The early and long-term effects of coronary artery ligation on the plasma and left ventricular angiotensin-converting enzyme (ACE and ACE2) activities, ACE and ACE2 mRNA levels, circulating angiotensin (Ang) levels [Ang ...
    • Olmedo, Ivonne; Muñoz, Claudia; Guzmán, Nancy; Catalán, Mabel; Vivar, Raúl; Ayala, Pedro; Humeres Martínez, Claudio; Aránguiz, Pablo; García Nannig, Lorena; Velarde, Victoria; Díaz Araya, Guillermo (Elsevier, 2013)
      In the heart, cardiac fibroblasts (CF) and cardiac myofibroblasts (CMF) are the main cells responsible for wound healing after cardiac insult. Exchange protein activated by cAMP (EPAC) is a downstream effector of cAMP, ...