Browsing by Title

Now showing items 43268-43287 of 91433

    • Genome-scale metabolic models of Microbacterium species isolated from a high altitude desert environment 
      Mandakovic, Dinka; Cintolesi, Ángela; Maldonado, Jonathan; Mendoza, Sebastián; Aite, Meziane; Gaete, Alexis; Saitua, Francisco; Allende, Miguel; Cambiazo Ayala, Liliana; Siegel, Anne; Maass Sepúlveda, Alejandro; González Canales, Mauricio; Latorre Mora, Mauricio (Nature, 2020)
      The Atacama Desert is the most arid desert on Earth, focus of important research activities related to microbial biodiversity studies. In this context, metabolic characterization of arid soil bacteria is crucial to understand ...
    • Genome-scale reconstruction of Salinispora tropica CNB-440 metabolism to study strain-specific adaptation 
      Contador, C. A.; Rodríguez, V.; Andrews Farrow, Bárbara; Asenjo, J. A. (Springer, 2015)
      The first manually curated genome-scale metabolic model for Salinispora tropica strain CNB-440 was constructed. The reconstruction enables characterization of the metabolic capabilities for understanding and modeling the ...
    • Genome-wide analyses reveal drivers of penguin diversification 
      Vianna, Juliana A.; Fernandes, Flavia A. N.; Frugone Wielandt, María José; Figueiro, Enrique V.; Pertierra, Luis R.; Nolla, Daly; Bi, Ke; Wang-Claypool, Cynthia Y.; Lowther, Andrew; Parker, Patricia; Le Bohec, Celine; Bonadonna, Francesco; Wienecke, Barbara; Pistorius, Pierre; Steinfurth, Antje; Burridge, Christopher P.; Dantas, Gisele P. M.; Poulin, Elie; Simison, W. Brian; Henderson, Jim; Eizirik, Eduardo; Nery, Mariana F.; Bowie, Rauri C. K. (National Academy of Sciences, 2020)
      Penguins are the only extant family of flightless diving birds. They currently comprise at least 18 species, distributed from polar to tropical environments in the Southern Hemisphere. The history of their diversification ...
    • Genome-wide analysis of genetic susceptibility to language impairment in an isolated Chilean population 
      Villanueva, Pia; Newbury, Dianne F.; Jara, Lilian; Barbieri Ortiz, Zulema de,; Mirza, Ghazala; Palamino, Hernán M.; Fernández, María Angélica; Cazier, Jean Baptiste; Monaco, Anthony P.; Palomino, Hernán (2011)
      Specific language impairment (SLI) is an unexpected deficit in the acquisition of language skills and affects between 5 and 8% of pre-school children. Despite its prevalence and high heritability, our understanding of the ...
    • Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human ... 
      DebRoy, Sruti; Aliaga Tobar, Víctor; Gálvez, Gabriel; Arora, Srishtee; Liang, Xiaowen; Horstmann, Nicola; Maracajá Coutinho, Vinicius; Latorre Mora, Mauricio; Hook, Magnus; Flores, Anthony; Shelburne, Samuel A. (Wiley, 2020)
      Catabolite control protein A (CcpA) is a master regulator of carbon source utilization and contributes to the virulence of numerous medically important Gram-positive bacteria. Most functional assessments of CcpA, including ...
    • Genome-wide analysis of somatic embryogenesis-related transcription factors in cultivated strawberry (fragaria ... 
      Garrido Bigotes, Adrián; Silva Ascencio, Herman Patricio; Hasbún, Rodrigo (MDPI, 2021)
      Somatic embryogenesis is a plant regeneration method commonly used in tissue culture. Its molecular mechanisms are well-known in model plants such as Arabidopsis thaliana L. LEAFY COTYLEDON1 (LEC1), LEAFY COTYLEDON2 (LEC2), ...
    • Genome-wide association analysis for body weight identifies candidate genes related to development and ... 
      Reis Neto, Rafael Vilhena; Yoshida, Grazyella Massako; Lhorente, Jean Paul; Yáñez López, José (Springer Verlag, 2019)
      Growth is one of the most important traits from both a physiological and economic perspective in aquaculture species. Thus, identifying the genomic regions and genes underpinning genetic variation for this trait is of ...
    • Genome-wide association analysis reveals loci associated with resistance against Piscirickettsia salmonis ... 
      Correa, Katharina; Lhorente, Jean Paul; López, María E.; Bassini, Liane; Naswa, Sudhir; Deeb, Nader; Di Genova, Alex; Maass Sepúlveda, Alejandro; Davidson, William S.; Yáñez López, José (BioMed Central, 2015)
      Background: Pisciricketssia salmonis is the causal agent of Salmon Rickettsial Syndrome (SRS), which affects salmon species and causes severe economic losses. Selective breeding for disease resistance represents one approach ...
    • Genome-Wide Association Study (GWAS) for Growth Rate and Age at Sexual Maturation in Atlantic Salmon (Salmo salar) 
      Gutiérrez, Alejandro P.; Yáñez López, José; Fukui, Steve; Swift, Bruce; Davidson, William S. (Public Library Science, 2015)
      Early sexual maturation is considered a serious drawback for Atlantic salmon aquaculture as it retards growth, increases production times and affects flesh quality. Although both growth and sexual maturation are thought ...
    • A genome-wide association study identifies multiple loci for variation in human ear morphology 
      Adhikari, Kaustubh; Reales, Guillermo; Smith, Andrew J.P.; Konka, Esra; Palmen, Jutta; Quinto Sánchez, Mirsha; Acuña Alonzo, Víctor; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Barquera Lozano, Rodrigo; Macín Pérez, Gastón; Gómez Valdés, Jorge; Villamil Ramírez, Hugo; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Gallo, Carla; Poletti, Giovanni; Schuler Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria Cátira; Canizales Quinteros, Samuel; Rothhammer Engel, Francisco; Bedoya, Gabriel; Calderón, Rosario; Rosique, Javier; Cheeseman, Michael; Bhutta, Mahmood F.; Humphries, Steve E.; González José, Rolando; Headon, Denis; Balding, David; Ruiz Linares, Andrés (Nature Publishing, 2015)
      Here we report a genome-wide association study for non-pathological pinna morphology in over 5,000 Latin Americans. We find genome-wide significant association at seven genomic regions affecting: lobe size and attachment, ...
    • Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in ... 
      Buchanan, Victoria L.; Wang, Yujie; Blanco, Estela; Graff, Mariaelisa; Albala Brevis, Cecilia; Burrows Argote, Raquel; Santos, José L.; Ángel, Barbara; Lozoff, Betsy; Voruganti, Venkata Saroja; Guo, Xiuqing; Taylor, Kent D.; Chen, Yii-Der Ida; Yao, Jie; Tan, Jingyi; Downie, Carolina; Highland, Heather M.; Justice, Anne E.; Gahagan, Sheila; North, Kari E. (Wiley, 2020)
      Background The genetic underpinnings of glycemic traits have been understudied in adolescent and Hispanic/Latino (H/L) populations in comparison to adults and populations of European ancestry. Objective To identify genetic ...
    • Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral ... 
      Matamala, José Manuel; Arias Carrasco, Raul; Sánchez, Carolina; Uhrig, Markus; Bargsted, Leslie; Matus, Soledad; Maracaja Coutinho, Vinicius; Abarzua, Sebastián; Van Zundert, Brigitte; Verdugo Latorre, Renato; Manque, Patricio; Hetz Flores, Claudio (Elsevier, 2018)
      The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
    • Genomewide single nucleotide polymorphism discovery in Atlantic salmon (Salmo salar): validation in wild ... 
      Yáñez López, José; Naswa, S.; López, M. E.; Bassini, Liane; Correa, K.; Gilbey, J.; Bernatchez, L.; Norris, A.; Lhorente, Jean Paul; Schnable, P. S.; Newman, S.; Mileham, A.; Deeb, N.; Di Genova, Alex; Maass Sepúlveda, Alejandro (2016)
      A considerable number of single nucleotide polymorphisms (SNPs) are required to elucidate genotype-phenotype associations and determine the molecular basis of important traits. In this work, we carried out de novo SNP ...
    • Genome‑scale comparative analysis for host Resistance against sea lice between Atlantic salmon and rainbow trout 
      Cáceres, Pablo; Barría, Agustín; Christensen, Kris A.; Bassini Ney, Liane; Correa, Katharina; García, Baltasar; Lhorente Causade, Jean Paul; Yáñez López, José Manuel (Nature Research, Germany, 2021)
      Sea lice (Caligus rogercresseyi) is an ectoparasite which causes major production losses in the salmon aquaculture industry worldwide. Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss) are two of the ...
    • Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical campylobacter ... 
      Bravo, Verónica; Katz Zondek, Assaf; Porte, Lorena; Weitzel, Thomas; Varela, Carmen; González Escalona, Narjol; BlondelI, Carlos J. (Public Library Science, 2021)
      Campylobacter jejuni and Campylobacter coli are the leading cause of human gastroenteritis in the industrialized world and an emerging threat in developing countries. The incidence of campylobacteriosis in South America ...
    • Genomic analysis of the domestication and post-Spanish conquest evolution of the llama and alpaca 
      Fan, Ruiwen; Gu, Zhongru; Guang, Xuanmin; Marín, Juan Carlos; Varas, Valeria; González Pérez, Benito; Wheeler, Jane C.; Hu, Yafei; Li, Elri; Sun, Xiaohui; Yang, Xukui; Zhang, Chi; Gao, Wenjun; He, Junping; Munch, Kasper; Corbett-Detig, Russel; Barbato, Mario; Pan, Shengkai; Zhan, Xiangjiang; Bruford, Michael W.; Dong, Changsheng (BMC, 2020)
      Background Despite their regional economic importance and being increasingly reared globally, the origins and evolution of the llama and alpaca remain poorly understood. Here we report reference genomes for the llama, and ...
    • Genomic and phenotypic comparison between similar wine yeast strains of Saccharomyces cerevisiae from ... 
      Salinas, F.; Mandakovic Seyler, Dinka; Urzúa Tobar, Ulises; Massera, A.; Miras, S.; Combina, M.; Ganga, M. Angélica; Martínez, C. (2010)
      Aims: To study genomic and phenotypic changes in wine yeasts produced in short time periods analysing yeast strains possibly derived from commercial strains recently dispersed. Methods and Results: We conducted a genomic ...
    • Genomic and SNP Analyses Demonstrate a Distant Separation of the Hospital and Community-Associated Clades ... 
      Galloway Peña, Jessica; Roh, Jung Hyeob; Latorre, Mauricio; Qin, Xiang; Murray, Barbara E. (PUBLIC LIBRARY SCIENCE, 2012-01-26)
      Recent studies have pointed to the existence of two subpopulations of Enterococcus faecium, one containing primarily commensal/community-associated (CA) strains and one that contains most clinical or hospital-associated ...
    • Genomic characterization of the non-O1/non-O139 Vibrio cholerae strain that caused a gastroenteritis outbreak ... 
      Arteaga Ortega, Mónica; Velasco, Juliana; Rodríguez, Shelly; Vidal, Maricel; Arellano, Carolina; Silva Ojeda, Francisco; Carreño Marquez, Leandro; Vidal Álvarez, Roberto; Montero, David (Microbiology Society, 2020)
      Vibrio cholerae is a human pathogen, which is transmitted by the consumption of contaminated food or water. V. cholerae strains belonging to the serogroups O1 and O139 can cause cholera outbreaks and epidemics, a severe ...
    • Genomic compatibility between two phyllotine rodent species evaluated through their hybrids 
      Walker Bozzo, Laura; Rojas, Mariana; Flores Carrasco, Sergio; Spotorno Oyarzún, Ángel; Manríquez Soto, Germán Raúl (1999)
      In order to investigate the genomic compatibility between allopatric rodent species, Phyllotis durivini and Pliyllotis mugister, we have studied several cytogenetic and reproductive features of their laboratory hybrids. ...