Now showing items 1-6 of 6

    • Briceño Catalán, Pedro Felipe; Rivas Yáñez, Elizabeth Camila; Rosemblatt Bono, Mariana Violeta; Parra Tello, Brian Josué; Farías, Paula; Vargas, Leonardo; Simon Zegers, María Valeska; Cárdenas, César; Lladser, Álvaro; Salazar Onfray, Flavio Andrés; Elorza, Álvaro A.; Rosemblatt Silber, Mario César; Bono Merino, María Rosa; Sauma Mahaluf, Daniela Macarena (Frontiers Media, 2021)
      CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development of immunosuppressive microenvironments. We have previously shown ...
    • Lobos González, Lorena; Aguilar, Lorena; Díaz Jara, Jorge; Díaz, Natalia; Urra, Hery; Torres Gómez, Vicente; Silva, Verónica; Fitzpatrick, Christopher; Lladser, Álvaro; Hoek, Keith S.; Leyton Campos, Lisette; Quest, Andrew F. G. (2013)
      Theroleofcaveolin-1(CAV1)incancerishighlycontroversial.CAV1suppressesgenesthatfavortumordevelopment, yet also promotes focal adhesion turnover and migration of metastatic cells. How these contrasting observations relate ...
    • Rosemblatt Bono, Mariana Violeta; Parra Tello, Brian Josué; Briceño Catalán, Pedro Felipe; Rivas Yáñez, Elizabeth Camila; Tucer, Suat; Saavedra Almarza, Juan Pablo; Hormann Cornejo, Pilar Leonor; Martínez, Brandon A.; Lladser, Álvaro; Rosemblatt Silber, Mario César; Cekic, Caglar; Bono Merino, María Rosa; Sauma Mahaluf, Daniela Macarena (Frontiers Media, 2021)
      Ecto-5 '-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is ...
    • Segovia Pavez, Raúl Emilio. (Universidad de Chile, 2018-03)
      El virus Andes (ANDV) pertenece al género Orthohantavirus (familia Hantaviridae, orden Bunyavirales). En humanos la infección por ANDV produce el síndrome pulmonar asociado a hantavirus, el cual presenta una tasa de ...
    • Lladser, Álvaro; Ljungberg, Karl; Tufvesson, Helena; Tazzari, Marcella; Roos, Anna-Karin; Quest, Andrew F. G.; Kiessling, Rolf (Springer-Verlag, 2010)
      Survivin is an intracellular tumor-associated antigen that is broadly expressed in a large variety of tumors and also in tumor associated endothelial cells but mostly absent in diVerentiated tissues. Naked DNA ...
    • Moncada, Claudio; Fuentes, Nelson; Lladser, Álvaro; Encina, Gonzalo; Sapag, Amalia; Karahanian, Eduardo; Israel Jacard, Yedy (PERGAMON-ELSEVIER SCIENCE LTD, 2003-08)
      The high-affinity (K-M < 1 muM) mitochondrial class 2 aldehyde dehydrogenase (ALDH2) metabolizes most of the acetaldehyde generated in the hepatic oxidation of ethanol. H4-II-E-C3 rat hepatoma cells have been found to ...