Now showing items 1-6 of 6

    • Moya Alvarado, Guillermo Adrian; Yáñez, Osvaldo; Morales, Nicole; González González, Angélica; Areche Medina, Carlos Alberto; Núñez González, Marco Tulio; Fierro, Angélica; García Beltrán, Olimpo José (MDPI, 2021)
      Fourteen coumarin-derived compounds modified at the C3 carbon of coumarin with an alpha,beta-unsaturated ketone were synthesized. These compounds may be designated as chalcocoumarins (3-cinnamoyl-2H-chromen-2-ones). Both ...
    • García Beltrán, Olimpo; Cassels Niven, Bruce; Mena, Natalia P.; Núñez González, Marco; Yáñez, Osvaldo; Caballero, Julio (Elsevier, 2014)
      In this Letter we present a new probe, (E)-7-(diethylamino)-2-oxo-2H-chromene-3-carbaldehyde oxime (JB), which can detect Cu2+ ions in HEPES buffer under physiological conditions. Benesi–Hildebrand and Job plots demonstrate ...
    • García Beltrán, Olimpo; Mena, Natalia P.; Yáñez, Osvaldo; Caballero, Julio; Vargas Cortés, Víctor; Núñez González, Marco; Cassels Niven, Bruce (2013)
      A new coumarin-based ‘turn-off’ fluorescent probe, 7-(diethylamino)-N-(1,3-dihydroxy-2-(hydroxymethyl) propan-2-yl)-2-oxo-2H-chromene-3-carboxamide (AGD) was synthesized. This compound is highly selective for ferrous ...
    • Ortiz, Andrea C.; Yáñez, Osvaldo; Salas Huenuleo, Edison Sebastián; Morales Montecinos, Javier Octavio (MDPI, 2021)
      Lipid nanocarriers have a great potential for improving the physicochemical characteristics and behavior of poorly water-soluble drugs, such as aqueous dispersibility and oral bioavailability. This investigation presents ...
    • Yáñez, Osvaldo; Osorio, Manuel Isaías; Uriarte, Eugenio; Areche Medina, Carlos Alberto; Tiznado, William; Pérez Donoso, José M.; García Beltrán, Olimpo José; González Nilo, Fernando Danilo (Frontiers Media, 2021)
      The pandemic that started in Wuhan (China) in 2019 has caused a large number of deaths, and infected people around the world due to the absence of effective therapy against coronavirus 2 of the severe acute respiratory ...
    • García Beltrán, Olimpo; Yáñez, Osvaldo; Caballero, Julio; Galdámez Silva, Antonio; Mena, Natalia P.; Núñez González, Marco; Cassels Niven, Bruce (Elsevier, 2014)
      Three coumarin-derived fluorescent probes, 3-acetyl-7-[(6-bromohexyl)oxy]-2H-chromen-2-one (FM1), 7-[(6-bromohexyl)oxy]-4-methyl-2H-chromen-2-one (FM2) and ethyl 2-{7-[(6-bromohexyl)oxy]-2-oxo- 2H-chromen-4-yl}acetate ...