Now showing items 1231-1250 of 2801

    • Sierpe, Rodrigo; Lang, Erika; Jara, Paul; Guerrero, Ariel; Chornik, Boris; Kogan Bocian, Marcelo; Yutronic Sáez, Nicolás (American Chemical Society, 2015)
      We report the synthesis of a 1:1 beta-cydodextrin-phenylethylamine (beta CD-PhEA) inclusion complex (IC) and the adhesion of gold nanoparticles (AuNPs) onto micro crystals of this complex, which forms a ternary system. The ...
    • Jara Guajardo, Pedro; Cabrera, Pablo; Celis, Freddy; Soler Jauma, Mónica; Berlanga Mora, Isadora; Parra Muñoz, Nicole; Acosta, Gerardo; Albericio, Fernando; Guzmán, Fanny; Campos, Marcelo; Álvarez, Alejandra; Morales Zavala, Francisco; Kogan, Marcelo J. (MDPI, 2020)
      The early detection of the amyloid beta peptide aggregates involved in Alzheimer's disease is crucial to test new potential treatments. In this research, we improved the detection of amyloid beta peptide aggregates in vitro ...
    • Asela, I.; Noyong, M.; Simon, U.; Andrades Lagos, Juan Andrés; Campanini Salinas, J.; Vásquez Velásquez, David; Kogan Bocian, Marcelo; Yutronic Sáez, Nicolás; Sierpe, R. (Public Library Science, 2017)
      While 2-amino-4-(4-chlorophenyl)thiazole (AT) drug and thiazole derivatives have several biological applications, these compounds present some drawbacks, such as low aqueous solubility and instability. A new complex of ...
    • Pedreschi, Franco; Bunger Timmermann, Andrea; Skurtys, Olivier; Allen, Paula; Rojas, Ximena (2012)
      Potato chips were classified in quality categories according to their color after frying at oil temperatures (120, 140, 160, and 180 ± 1 °C) and undergoing some pre-treatments (control or unblanching, blanching, and blanching ...
    • Almada, M.; Ruiz, E. D.; Ibarra Hurtado, J.; Hassan, N.; Kogan Bocian, Marcelo; Cadena Nava, R. D.; Valdés, M. A.; Juarez, J. (Amer Scientific, 2016)
      A systematic study of the effect of ascorbic acid concentration on the growth kinetics of gold nanorods under pH acidic conditions was done. We employed the seed-mediated approach at pH 1.25 using different ascorbic acid/Au+3 ...
    • Bravo Rodríguez, Denisse; Silva Valenzuela, Cecilia Alejandra; Carter Jaña, Javier Antonio; Hoare Teuche, Anilei Paz; Álvarez Armijo, Sergio Aníbal; Blondel, Carlos; Zaldívar San Román, María Mercedes; Valvano, Miguel A.; Contreras, Inés (SOC GENERAL MICROBIOLOGYJournal Of Medical Microbiology, vol. 57 Issue 8 p. 938-946 AUG 2008, 2008-08)
      The amount of lipopolysaccharide (LPS) O antigen (OAg) and its chain length distribution are important factors that protect bacteria from serum complement. Salmonella enterica serovar Typhi produces LPS with long chain ...
    • Sapag Muñoz de la Peña, Amalia; Irarrázaval Aguilera, Thergiorg; Lobos González, Lorena; Muñoz Brauning, Carlos; Quintanilla González, María Elena; Tampier de Jong, Lutske (Nature Publishing Group, 2016)
      Ribozyme genes were designed to reduce voluntary alcohol drinking in a rat model of alcohol dependence. Acetaldehyde generated from alcohol in the liver is metabolized by the mitochondrial aldehyde dehydrogenase (ALDH2) ...
    • Cancino Rivera, Patricio Antonio; Astudillo, Luis; Rovirosa, Juana; San Martín Barrientos, Aurelio (1987)
    • Zapata Urzúa, Claudio; Pérez Ortiz, Magdalena; Acosta, Gerardo A.; Mendoza, Joan; Yedra, Lluis; Estradé, Sonia; Álvarez Lueje, Alejandro; Núñez Vergara, Luis; Albericio, Fernando; Lavilla, Rodolfo; Kogan Bocian, Marcelo (Elsevier, 2015)
      Anisotropic and branched gold nanoparticles have great potential in optical, chemical and biomedical applications. However their syntheses involve multi-step protocols and the use of cytotoxic agents. Here, we report a ...
    • Yañez Valdés, María Francisca (2014)
      We present a unified approach to the study of Radon transforms related to symmetric groups and to general linear groups GLn(q), regarded as q−analogues of the former. In both cases, we define a sequence of generalized ...
    • Toledo, Carla; Enríquez, Pedro; Garrido, Mariano; Fernández-Band, Beatríz; Richter Duk, Pablo (TAYLOR & FRANCIS INC, 2010)
      A headspace-mass spectrometry with alternative chromatographic separation using a column switching system was developed for the screening and confirmation of BTEX and styrene in comestible oils. According to the position ...
    • García, Vivian; Uribe, Elsa; Vega Gálvez, Antonio; Delporte Vergara, Carla; Valenzuela Barra, Gabriela; López, Jéssica; Pasten, Alexis (Sociedad Chilena de Nutrición, 2020)
      The aim of this study was to evaluate the antioxidant, antidiabetic, anti-inflammatory and antimicrobial activities of three edible seaweed extracts from Chilean coasts: Pyropia orbicularis, Ulva spp, and Durvillaea ...
    • Riedel, Clement; Gabizon, Ronen; Wilson Moya, Christian; Hamadani, Kambiz; Tsekouras, Konstantinos; Marqusee, Susan; Presse, Steve; Bustamante, Carlos (Macmillan, 2015)
      Recent studies have shown that the diffusivity of enzymes increases in a substrate-dependent manner during catalysis1,2. Although this observation has been reported and characterized for several different systems3–10, ...
    • Schalscha B., Eduardo; Ahumada Torres, Aída Inés de Lourdes (PERGAMON-ELSEVIER SCIENCE LTD, 1998)
      Industrial and domestic waste waters in Chile are discharged without previous treatment into rivers and other inland waters which are used to irrigate agricultural lands. The present study reports on results obtained when ...
    • Valenzuela, Manuel A.; Canales, Jimena; Corvalán, Alejandro H.; Quest, Andrew F. G. (Baishideng Publishing Group Inc., 2015)
      The sequence of events associated with the development of gastric cancer has been described as "the gastric precancerous cascade". This cascade is a dynamic process that includes lesions, such as atrophic gastritis, ...
    • Calderón, Inés; Lobos, S.; Mora, Guido C. (Springer-Verlag, 1984)
      Two outer membrane proteins of Salmonella typhi T y 2 were extensively co-purified. According to their migration in dodecyl sulfate/polyacrylamide gel electrophoresis and solubility characteristics, these proteins are ...
    • Olivares Silva, Francisco Javier; Landaeta, Rodolfo; Aránguiz, Pablo; Bolivar, Samir; Humeres Martínez, Claudio; Anfossi, Renatto; Vivar Sánchez, Raúl; Boza Fuentes, Pía; Muñoz Jofré, Claudia; Pardo Jiménez, Viviana Gladys; Peiro, Concepción; Sánchez Ferrer, Carlos; Díaz Araya, Guillermo (Elsevier, 2018)
      Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the ...
    • Mena, Natalia P.; Esparza, Andrés; Tapia, Victoria; Valdés, Pamela; Núñez González, Marco (2007)
      Hepcidin (Hepc) is considered a key mediator in iron trafficking. Although the mechanism of Hepc action in macrophages is fairly well established, much less is known about its action in intestinal cells, one of the main ...
    • Letelier, María E.; Iturra Montecinos, Pablo; Gallardo Garrido, Carlos (Universidad de Santiago de Chile, 2017)
      Inflammation is a cellular defensive mechanism associated to oxidative stress. The administration of nitrofurantoin, nifurtimox and acetaminophen generates oxidative stress by their biotransformation through CYP450 system. ...
    • Paredes, Felipe; Parra, Valentina; Torrealba, Natalia; Navarro Márquez, Mario F.; Gatica, Damián; Bravo Sagua, Roberto; Troncoso, Rodrigo; Pennanen, Christian; Quiroga, Clara; Chiong Lay, Mario; Caesar, Christa; Taylor, W. Robert; Molgó, Jordi; San Martín, Alejandra; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Elsevier, 2016)
      Homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 1 (HERPUD1), an ER resident protein, is upregulated in response to ER stress and Ca2(+) homeostasis deregulation. HERPUD1 ...