Now showing items 2115-2134 of 2801

    • Shaikh, Soni; Troncoso Cotal, Rodrigo; Criollo Céspedes, Alfredo; Bravo Sagua, Roberto; García Nannig, Lorena; Morselli, Eugenia; Cifuentes, Mariana; Quest, Andrew F. G.; Hill, Joseph A.; Lavandero González, Sergio (Amer Physiological Soc, 2016)
      Calcium signaling plays a crucial role in a multitude of events within the cardiomyocyte, including cell cycle control, growth, apoptosis, and autophagy. With respect to calcium-dependent regulation of autophagy, ion ...
    • Tapia, Victoria; Arredondo, Miguel; Núñez González, Marco (1996)
      Body Fe homeostasis is maintained through the regulation of Fe absorption by the intestinal epithelia. Working under the hypothesis that the intracellular concentration of Fe is instrumental in the control of its transepithelial ...
    • Mondaca Ruff, David Gonzalo; Quiroga, Clara; Norambuena Soto, Ignacio Estebán; Riquelme Meléndez, Jaime Andrés; San Martin, Alejandra; Bustamante Parraguez, Mario Andrés; Lavandero González, Sergio Alejandro; Chiong Lay, Mario Martín (Wiley, 2022)
      Hypertension is associated with high circulating angiotensin II (Ang II). We have reported that autophagy regulates Ang II-induced vascular smooth muscle cell (VSMC) hypertrophy, but the mechanism mediating this effect is ...
    • Rojas Rivera, Andrés; Díaz Elizondo, Jessica; Parra Ortíz, María Valentina; Salas, Daniela; Contreras Ferrat, Ariel Eduardo; Toro, Barbra; Chiong Lay, Mario; Olea Azar, Claudio; Lavandero González, Sergio (ELSEVIER SCIENCE BV, 2009-11-03)
      We investigated the role of Ca2+ in generating reactive oxygen species (ROS) induced by hyposmotic stress (Hypo) and its relationship to regulatory volume decrease (RVD) in cardiomyocytes. Hypo-induced increases in cytoplasmic ...
    • Castro, Pablo; Greig, Douglas; Pérez, Osvaldo; Moraga, Francisco; Chiong Lay, Mario; Díaz Araya, Guillermo; Padilla, Ivonne; Nazzal Nazal, Carolina; Jalil Milad, Jorge; Vukasovic Ramírez, José Luis; Moreno, M.; Corbalán, Ramón; Lavandero González, Sergio (EXCERPTA MEDICA INC, 2003-07-15)
    • Cárdenas Jirón, G.; Gutiérrez Oliva, Soledad; Melin, Junia; Toro Labbé, Alejandro (American Chemical Society, 1997)
      In recent papers we defined a theoretical frame aimed at characterizing the hardness and potential energy profiles along a reduced reaction coordinate (omega) varying from 0 to 1. In this paper we generalize that model to ...
    • Cebrero, Gonzalo; Sanhueza, Óscar; Pezoa, Matías; Báez Contreras, María E.; Martínez, Jessica; Báez Larach, Mauricio; Fuentes Pérez, Edwar (Elsevier, 2020)
      Some minor constituents of honey samples were determined through a fluorometric-chemical characterization method and related multifactorially with their antibacterial activity against Staphylococcus aureus and Pseudomonas ...
    • Castro, Pablo; Winter, José Luis; Verdejo, Hugo; Orellana, Pilar; Quintana, Juan Carlos; Greig, Douglas; Enríquez, Andrés; Sepúlveda, Luis; Concepción, Roberto; Sepúlveda, Pablo; Rossel Mariángel, Víctor; Chiong Lay, Mario; García Nannig, Lorena; Lavandero González, Sergio (2012)
      Background Ventricular dyssynchrony is a common finding in patients with heart failure (HF), especially in the presence of conduction delays. The loss of ventricular synchrony leads to progressive impairment of contractile ...
    • Fernández, Luciana A.; Santo, Marisa R.; Reta, Mario; Giacomelli, Liliana; Cattana, Rosa; Silber, Juana J.; Risso, Mariela; Cerecetto, Hugo; González, Mercedes; Olea Azar, Claudio (MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, 2005-09)
      The relationship between the herbicidal activity of a number of novel 1,2,5- oxadiazole N-oxides and some physicochemical properties potentially related with this bioactivity, such as polarity, molecular volume, proton ...
    • Macho Fisher, Pilar; Domenech Lira, Raúl; Penna Varela, Mario (1995)
      The metabolites that mediate coronary reactive hyperemia have not been definitely identified. Although adenosine and endothelium derived substances seem to be involved, their relative contributions have not been defined ...
    • Ortíz Yáñez, María Eugenia; Núñez Vergara, Luis; Squella Serrano, Juan (KLUWER ACADEMIC/PLENUM PUBL, 2003-02)
      Purpose. To evaluate the reaction of a large series of pharmacologically significant 1,4-dihydropyridine (1,4-DHP) compounds with superoxide (O-2(.-)) in dimethylsulfoxide using differential pulse voltammetry and controlled ...
    • García, Paula; Vergara, Cristina; Robert Canales, Paz (Institute of Food Technologists, 2015)
      Gallic acid (GA) was encapsulated with native (NIn), cross-linked (CIn) and acetylated (AIn) inulin by spray-drying. Inulin microparticles were characterized by encapsulation efficiency (EE) and their release profile in ...
    • Palma, Manuel; García, Paula; Márquez-Ruiz, Gloria; Vergara, Cristina; Robert Canales, Paz (Elsevier Ltd, 2014)
      Quercetin (Q), naringenin (N) and epicatechin (E) were encapsulated with inulin (In) as encapsulating agent and Capsul (C) as channelizing agent by spray drying and applying a Box-Behnken design. Q-In, N-In, E-In, Q-In-C, ...
    • Zanocco Loyola, Antonio; Günther Sapunar, Germán; Lemp Miranda, Else; Lissi Gervaso, Eduardo A. (1998)
      The cationic dye Methylene Blue included in the internal aqueous microphase of dioctadecyldimethylammonium chloride (DODAC) vesicle shows the typical monomer–dimer equilibrium observed in homogenous aqueous solutions. ...
    • Lara Peñaloza, Hernán; Porcile, Arnaldo; Espinoza, Jaime; Romero Osses, Carmen; Luza, Sandra M.; Fuhrer, Juan; Miranda, Cristian; Roblero, Luis (2001)
      We investigated the possibility that norepinephrine from the human ovary is released after nerve stimulation and that this neurotransmitter is coupled to a steroidogenic response. Biologically significant levels of both ...
    • Jachero, Lourdes; Claudio, Leiva; Ahumada Torres, Aída Inés; Richter Duk, Pablo (Springer, 2017)
      The bioavailability of polychlorinated biphenyls (PCBs) in soils amended with biosolids was estimated using an aqueous leaching process of the compounds combined with rotating disk sorptive extraction (RDSE), and compared ...
    • Riquelme, Sebastián; Varas, Macarena; Valenzuela, Camila; Velozo Hermosilla, Paula Elizabeth; Chahin, Nicolás; Aguilera, Paulina; Sabag, Andrea; Labra, Bayron; Álvarez Armijo, Sergio; Chávez, Francisco P.; Santiviago Cid, Carlos (Frontiers Media, 2016)
      The social amoeba Dictyostelium discoideum has proven to be a useful model for studying relevant aspects of the host-pathogen interaction. In this work, D. discoideum was used as a model to study the ability of Salmonella ...
    • Matos, Maria João; Pérez Cruz, Fernanda; Vazquez Rodriguez, Saleta; Uriarte, Eugenio; Santana, Lourdes; Borges, Fernanda; Olea Azar, Claudio (Elsevier, 2013)
      In the present work we synthesized a series of hydroxy-3-arylcoumarins (compounds 1–9), some of them previously described as MAO-B selective inhibitors, with the aim of evaluating their antioxidant properties. Theoretical ...
    • Machado, Marcio; Iskedjian, Michael; Ruiz, Inés; Einarson, Thomas R. (LIBRAPHARM, 2006-09)
      Objective: To summarize remission rates and dropouts due to adverse drug reactions (ADRs) or lack of efficacy (LoE) of serotonin-norepinephrine reuptake inhibitors (SNRIs), selective serotonin-reuptake inhibitors (SSRIs), ...