Now showing items 1165-1184 of 11550

    • Vergara Iturriaga, Marcos; Bisama, Ligia (Universidad de Chile, 2010)
    • Collao Parra, Juan Pablo; Romero Urra, César; Delgado Derio, Carolina (Sociedad Medica de Santiago, 2018)
      © 2018, Sociedad Medica de Santiago. All Rights reserved.Autoimmune encephalitis are one of the emergent causes of subacute changes in the level of consciousness, behavior, cognitive impairment and seizures, mainly in young ...
    • Pérez,; Rodríguez Rodríguez, Pablo Andrés; Sepúlveda Sepúlveda, Ximena Andrea; Silva Silva, Laura (1991)
      We analyzed sera from 102 subjects older than 65 years of age with no clinical evidence of autoimmune disorders, inflammatory diseases or pharmacological interventions. Positive titers for antinuclear antibodies were found ...
    • Devoto, Enzo; Aravena C., Lucia; Corvalán M., Luis; Lioi C., Ximena; Munizaga, Fernando; Soto I., Nestor; Hidalgo V., M. Soledad; Barrera R., Radek; Gajardo L., Hector (1990)
      The autoimmune polyglandular syndrome is characterized by the association of 2 or more endocrine disorders of autoimmune origin which may coexist with autoimmune disorders in other organs. Roughly 25% of patients with an ...
    • Flores P, Claudio; Conte L, Guillermo; Fardella B, Patricia; Araos H, Daniel; Alfaro L, Jorge; Aravena R, Paola; González G, Néstor; Larrondo L, Milton (2005)
      Background: Multiple myeloma is rarely curable. Advances in high dose chemotherapy and stem cell transplantation have improved overall survival and event-free disease periods, but relapses are inevitable. Aim: To report ...
    • Aubourg, Santiago P.; Quitral Robles, Vilma; Larraín Barth, María Angélica; Rodríguez Melis, Alicia; Gómez, Julio; Maier Neumann, Liliana Cristina; Vinagre, Julia (Elsevier, 2007)
      Two deteriorative pathways (autolysis and microbiological activity) were studied in farmed Coho salmon (Oncorhynchus kisutch) for 24 days during chilled storage. These changes were assessed by nucleotide degradation ...
    • Figueroa Barra, Alicia Ivonne Eduvigis; Aguila, Daniel del; Cerda Villablanca, Mauricio David; Gaspar Ramos, Pablo Arturo; Terissi, Lucas D.; Durán, Manuel; Valderrama Vega, Camila Fernanda (Nature, 2022)
      Automated language analysis of speech has been shown to distinguish healthy control (HC) vs chronic schizophrenia (SZ) groups, yet the predictive power on first-episode psychosis patients (FEP) and the generalization to ...
    • Gajardo, Abraham I.J.; Karachon, Lukas; Bustamante, Pablo; Repullo, Pablo; Llancaqueo, Marcelo; Sánchez, Gina; Rodrigo Salinas, Ramón (Churchill Livingstone, 2018)
      © 2018 Elsevier Ltd Remote ischemic preconditioning (RIPC) is a cardioprotective strategy against myocardial damage by ischemia-reperfusion. Many in-vivo and ex-vivo animal researches have demonstrated that RIPC decreases ...
    • Benrick, Anna; Kokosar, Milana; Hu, Min; Larsson, Martin; Maliqueo Yevilao, Manuel; Marcondes, Rodrigo Rodrigues; Soligo, Marzia; Protto, Virginia; Jerlhag, Elisabet; Sazonova, Antonina; Behre, Carl Johan; Højlund, Kurt; Thorén, Peter; Stener-Victorin, Elisabet (FASEB, 2017)
      © FASEB A single bout of low-frequency electroacupuncture (EA) causing muscle contractions increases wholebody glucose uptake in insulin-resistant rats.We explored the underlyingmechanism of this finding andwhether it can ...
    • Gajardo Cortez, Abraham; Madariaga, Samuel; Maldonado Arbogast, Pedro (Churchill Livingstone, 2019)
      Background: Cardiovascular risk (CVR) biomarkers are of increasing interest because of their potential utility in management of cardiovascular diseases. The activity of the autonomic nervous system (ANS) is known to be ...
    • Moreno, Ximena; Huerta, Martín; Albala Brevis, Cecilia (Elsevier, 2014)
      Objetivo: Explorar la asociación entre autopercepción de salud general negativa y mortalidad en adultos mayores. Método: Revisión sistemática cuyos criterios de inclusión fueron estudios longitudinales, evaluación de la ...
    • González, Alexis E.; Muñoz, Vanessa C.; Cavieres, Viviana A.; Bustamante, Hianara A.; Cornejo, Víctor Hugo; Januário, Yunan C.; González, Ibeth; Hetz Flores, Claudio; Dasilva, Luis L.; Rojas-Fernández, Alejandro; Hay, Ronald T.; Mardones, Gonzalo A.; Burgos, Patricia V. (FASEB, 2017)
      © FASEB. Brain regions affected by Alzheimer disease (AD) displaywell-recognized early neuropathologic features in the endolysosomal and autophagy systems of neurons, including enlargement of endosomal compartments, ...
    • Peña Oyarzún, Daniel; Bravo Sagua, Roberto; Díaz Vega, Alexis; Aleman, Larissa; Chiong Lay, Mario; García Nannig, Lorena; Bambs, Claudia; Troncoso, Rodrigo; Cifuentes, Mariana; Morselli, Eugenia; Ferreccio, Catterina; Quest, Andrew F. G.; Criollo Céspedes, Alfredo; Lavandero González, Sergio (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Non-communicable diseases (NCDs), also known as chronic diseases, are long-lasting conditions that affect millions of people around the world. Different factors contribute to their genesis and progression; ...
    • Nemchenko, Andriy; Chiong Lay, Mario; Turer, Aslan; Lavandero González, Sergio; Hill, Joseph A. (2011)
      The epidemic of heart failure continues apace, and development of novel therapies with clinical efficacy has lagged. Now, important insights into the molecular circuitry of cardiovascular autophagy have raised the prospect ...
    • Hazari, Younis M.; Bravo San Pedro, José Manuel; Hetz Flores, Claudio; Galluzzi, Lorenzo; Kroemer, Guido (Elsevier, 2020)
      Autophagy is an evolutionarily ancient process whereby eukaryotic cells eliminate disposable or potentially dangerous cytoplasmic material, to support bioenergetic metabolism and adapt to stress. Accumulating evidence ...
    • Mattar, Pamela; Bravo Sagua, Roberto; Tobar, Nicolás; Fuentes, Cecilia; Troncoso, Rodrigo; Breitwieser, Gerda; Lavandero González, Sergio; Cifuentes, Mariana (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Obesity is a major current public health problem worldwide due to the severe co-morbid conditions that this disease entails. The development of obesity-related cardiometabolic disorders is in direct ...
    • Matus, Soledad; Bosco, Daryl A.; Hetz Flores, Claudio (Elsevier, 2014)
      Mutations in fused in sarcoma and/or translocated in liposarcoma (FUS, TLS or FUS) are linked to familial cases of amyotrophic lateral sclerosis (ALS). Mutant FUS selectively accumulates into discrete cytosolic structures ...
    • Paris Pizarro, Irmgard; Muñoz, Patricia; Huenchuguala, Sandro; Couve, Eduardo; Sanders, Laurie H.; Greenamyre, John Timothy; Caviedes, Pablo; Segura Aguilar, Juan (2011)
      Aminochrome, the precursor of neuromelanin, has been proposed to be involved in the neurodegeneration neuromelanincontaining dopaminergic neurons in Parkinson's disease. We aimed to study the mechanism of aminochrome-dependent ...
    • Silva, Victor D.A.; Urriola Cuevas, Carlos; Muñoz, Patricia; Villa, Monica; Ahumada-Castro, Ulises; Huenchuguala, Sandro; Dos Santos, Cleonice C.; De Araujo, Fillipe M.; Ferreira, Rafael; Da Silva, Vanessa B.; Silva, Juliana H.C.; Soares, Érica N.; Velozo, Eudes S.; Segura Aguilar, Juan (Academia Brasileira de Ciencias, 2017)
      © 2017, Academia Brasileira de Ciencias. All rights reserved. Prosopis juliflora is a shrub that has been used to feed animals and humans. However, a synergistic action of piperidine alkaloids has been suggested to be ...
    • Budini, Mauricio; Jacob, Germaine; Jedlicki, Ana; Pérez, Carolina; Allende, Catherine C.; Allende, Jorge E. (2009)
      CK1 constitutes a protein kinase subfamily that is involved in many important physiological processes. However, there is limited knowledge about mechanisms that regulate their activity. Isoforms CK1δ and CKlε were previously ...