Now showing items 360-379 of 854

    • Gangiredla, Jayanthi; Rand, Hugh; Benisatto, Daniel; Payne, Justin; Strittmatter, Charles; Sanders, Jimmy; Wolfgang, William J.; Libuit, Kevin; Herrick, James B.; Prarat, Melanie; Toro Ibaceta, Magaly Alejandra; Farrell, Thomas; Strain, Errol (BMC, 2021)
      Background: Processing and analyzing whole genome sequencing (WGS) is computationally intense: a single Illumina MiSeq WGS run produces ~ 1 million 250-base-pair reads for each of 24 samples. This poses significant obstacles ...
    • Guil Guerrero, José Luis; González Fernández, María José; Lyashenko, Svetlana; Fabrikov, Dmitri; Rincón Cervera, Miguel Ángel; Urrestarazu, Miguel; Gómez Mercado, Francisco (Wiley, 2020)
      Thirty Boraginaceae species from different tribes were evaluated in a search of gamma-linolenic (GLA, 18:3n-6) and stearidonic acid (SDA, 18:4n-3)-rich oils. The high GLA percentages were found in the seed oils of Symphytum ...
    • Viana Campos, Ana Cristina; Albala Brevis, Cecilia; Lera Marques, Lydia; Sánchez Reyes, Hugo; Duarte Vargas, Andrea María; Ferreira e Ferreira, Efigenia (Biomed Central, 2015)
      Background: The determinants of self-rated health (SRH) have been widely investigated to explain social differences and gender differences in health. This study aimed to investigate the gender differences in predictors ...
    • Moreno, Ximena; Albala Brevis, Cecilia; Lera Marques, Lydia; Leyton Dinamarca, Bárbara; Angel Badillo, Bárbara Karen; Sánchez, Hugo (Public Library Science, 2018)
      Background This study was aimed to estimate life expectancy (LE), disability-free life expectancy (DFLE) and disabled life expectancy (DLE) among older adults from Santiago, Chile, and to determine the existence of ...
    • Rojas Baechler, Cecilia; Martínez, Jessica I.; Flores, Ingrid; Hoffman, Dennis R.; Uauy Dagach-Imbarack, Ricardo (ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2003-07)
      PURPOSE. To explore the effect of docosahexaenoic acid (DHA) on gene expression during human fetal retinal maturation. METHODS. Human fetal retinal explants were cultured in serum-free Waymouth's medium supplemented ...
    • Pozo, Talía del; Cambiazo Ayala, Liliana; González Canales, Mauricio (ELSEVIER, 2010)
      As a result of copper essentiality for life, plants and most other organisms have developed a conserved and complex network of proteins to handling Cu in order to prevent its deficit and to avoid its potentially toxic ...
    • Armendáriz, Angela D.; Olivares, Felipe; Pulgar Tejo, Rodrigo; Loguinov, Alex; Cambiazo Ayala, Liliana; Vulpe, Christopher D.; González Canales, Mauricio (2006)
      The role of metallothioneins (MT) in copper homeostasis is of great interest, as it appears to be partially responsible for the regulation of intracellular copper levels during adaptation to extracellular excess of ...
    • Mardones, Lorena; Petermann Rocha, Fanny Emily; Martínez Sanguinetti, María Adela; Leiva, Ana María; Troncoso Pantoja, Claudia Andrea; Martorell, Miquel; Lasserre, Nicole; Ulloa, Natalia; Pérez Bravo, Francisco Antonio; Celis Morales, Carlos; Villagrán, Marcelo (SBEM-Soc Brasil Endocrinologia & Metabologia, 2021)
      Objective: To study the association of SLC16A11 gene variants with obesity and metabolic markers in nondiabetic Chilean adults. Materials and methods: This cross-sectional study included 263 nondiabetic adults. The ...
    • Busch, Alexander S.; Hagen, Casper P.; Main, Katharina M.; Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Almstrup, Kristian; Mericq, Verónica; Juul, Anders (Oxford Academic, 2017)
      Context: Although genetic factors play a pivotal role in male pubertal timing, genome-wide association studies have identified only a few loci. Genetic variation of follicle-stimulating hormone (FSH) action affects adult ...
    • Argüello, Graciela; Balboa, Elisa; Tapia, Pablo J.; Castro, Juan; Yáñez, María José; Mattar, Pamela; Pulgar Tejo, Rodrigo Enrique; Zanlungo, Silvana (MDPI, 2021)
      Niemann-Pick type C disease (NPCD) is a lysosomal storage disease (LSD) characterized by abnormal cholesterol accumulation in lysosomes, impaired autophagy flux, and lysosomal dysfunction. The activation of transcription ...
    • Hödar Quiroga, Christian; Moreno, Pablo; Genova, Alex di; Latorre, Mauricio; Reyes Jara, Angélica; Maass Sepúlveda, Alejandro; González Canales, Mauricio; Cambiazo Ayala, Liliana (Springer, 2012)
      Acidithiobacillus ferrooxidans is a chemolithoautotrophic acidophilic bacterium that obtains its energy from the oxidation of ferrous iron, elemental sulfur, or reduced sulfur minerals. This capability makes it of great ...
    • Mandakovic, Dinka; Cintolesi, Ángela; Maldonado, Jonathan; Mendoza, Sebastián; Aite, Meziane; Gaete, Alexis; Saitua, Francisco; Allende, Miguel; Cambiazo Ayala, Liliana; Siegel, Anne; Maass Sepúlveda, Alejandro; González Canales, Mauricio; Latorre Mora, Mauricio (Nature, 2020)
      The Atacama Desert is the most arid desert on Earth, focus of important research activities related to microbial biodiversity studies. In this context, metabolic characterization of arid soil bacteria is crucial to understand ...
    • Buchanan, Victoria L.; Wang, Yujie; Blanco, Estela; Graff, Mariaelisa; Albala Brevis, Cecilia; Burrows Argote, Raquel; Santos, José L.; Ángel, Barbara; Lozoff, Betsy; Voruganti, Venkata Saroja; Guo, Xiuqing; Taylor, Kent D.; Chen, Yii-Der Ida; Yao, Jie; Tan, Jingyi; Downie, Carolina; Highland, Heather M.; Justice, Anne E.; Gahagan, Sheila; North, Kari E. (Wiley, 2020)
      Background The genetic underpinnings of glycemic traits have been understudied in adolescent and Hispanic/Latino (H/L) populations in comparison to adults and populations of European ancestry. Objective To identify genetic ...
    • Galloway Peña, Jessica; Roh, Jung Hyeob; Latorre, Mauricio; Qin, Xiang; Murray, Barbara E. (PUBLIC LIBRARY SCIENCE, 2012-01-26)
      Recent studies have pointed to the existence of two subpopulations of Enterococcus faecium, one containing primarily commensal/community-associated (CA) strains and one that contains most clinical or hospital-associated ...
    • Castillo, Daniel; Espejo Torres, Romilio; Middelboe, Mathias (John Wiley & Sons, 2014)
      Flavobacterium psychrophilum is currently one of the most devastating fish pathogens worldwide causing considerable economic losses in salmonid aquaculture. Recently, attention has been drawn to the use of phages for ...
    • Mandakovic, Dinka; Glasner, Benjamín; Maldonado, Jonathan; Aravena, Pamela; González, Mauricio; Cambiazo Ayala, Verónica; Pulgar Tejo, Rodrigo (Frontiers Media, 2016)
      The gram negative facultative bacterium P. salmonis is the etiological agent of Salmonid Rickettsial Septicaemia (SRS), a severe disease that causes important economic losses in the global salmon farmer industry. Despite ...
    • Garmendia Miguel, María Luisa; Matus, O.; Mondschein, S.; Kusanovic, J. P. (Elsevier, 2018)
      Objectives: We examined if the guidelines for gestational weight gain (GWG) proposed by the Institute of Medicine (IOM) are the most suitable for Chilean women. Study design: Secondary analysis of records of single ...
    • Kuhn, Nathalie; Ponce, Claudio; Arellano, Macarena; Time, Alson; Sagredo, Boris; Donoso, José Manuel; Meisel, Lee A. (MDPI, 2020)
      Several phytohormones modulate ripening in non-climacteric fruits, which is triggered by abscisic acid (ABA). Gibberellins (GAs) are present during the onset of ripening in sweet cherry fruits, and exogenous gibberellic ...
    • Mora, Rodrigo; Weisstaub Nuta, Sergio (Soc. Medica de Santiago, 2016)
    • Sparling, Thalia M.; Cheng, Bryan; Deeney, Megan; Santoso, Marianne V.; Pfeiffer, Erin; Emerson, Jillian A.; Amadi, Florence Mariamu; Mitu, Khadija; Corvalán Aguilar, Camila; Verdeli, Helen; Araya, Ricardo; Kadiyala, Suneetha (Frontiers Media, 2021)
      Both malnutrition and poor mental health are leading sources of global mortality, disease, and disability. The fields of global food security and nutrition (FSN) and mental health have historically been seen as separate ...