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Authordc.contributor.authorDutzan Muñoz, Nicolás 
Authordc.contributor.authorAbusleme Ramos, Loreto Andrea 
Authordc.contributor.authorMoutsopoulos, Niki 
Admission datedc.date.accessioned2021-05-23T20:23:43Z
Available datedc.date.available2021-05-23T20:23:43Z
Publication datedc.date.issued2020
Cita de ítemdc.identifier.citationEn: Sahingur S. (eds) Emerging Therapies in Periodontics. Springer, Cham. 2020es_ES
Identifierdc.identifier.otherhttps://doi.org/10.1007/978-3-030-42990-4_6
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/179744
Abstractdc.description.abstractThe Th17/IL-17 axis has been implicated in the pathogenesis of several inflammatory and autoimmune diseases including psoriasis, rheumatoid arthritis, and periodontitis. Indeed, in periodontitis, recent studies have further highlighted the role of the Th17/IL-17 axis in mediating immunopathology underscoring this pathway as a plausible therapeutic target for this disease. In this chapter, we focused not only on the role of IL-17A during immunopathology but also on its protective roles at mucosal barrier sites. We discussed the role of Th17 cells and IL-17A in oral mucosa homeostasis, their regulation and role in periodontal immunopathology. Finally, we reviewed the currently used agents for the management of Th17/IL-17 mediated diseases and commented on their possible use in the treatment of periodontitis.es_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherSpringeres_ES
Sourcedc.sourceEmerging Therapies in Periodonticses_ES
Keywordsdc.subjectTh17es_ES
Keywordsdc.subjectIL-17es_ES
Keywordsdc.subjectPeriodontitises_ES
Keywordsdc.subjectImmunopathologyes_ES
Keywordsdc.subjectInflammationes_ES
Keywordsdc.subjectTherapyes_ES
Keywordsdc.subjectTargetes_ES
Keywordsdc.subjectOrales_ES
Keywordsdc.subjectMucosaes_ES
Keywordsdc.subjectGingivaes_ES
Títulodc.titleThe IL-17/Th17 Axis as a Therapeutic Target in Periodontitises_ES
Document typedc.typeCapítulo de libroes_ES
dcterms.accessRightsdcterms.accessRightsAcceso a solo metadatoses_ES
Catalogueruchile.catalogadorlajes_ES


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