Browsing by Author "01026887-3936-4f42-ad37-0ec9daee6307"

Now showing items 1-4 of 4

    • Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? 
      Abello Cáceres, Paula; Pizarro Bauerle, Javier; Rosas Chuñil, Carlos Alberto; Maldonado, Ismael; Aguilar Guzmán, Lorena Andrea; González Guevara, Carlos Mauricio; Ramírez Toloza, Galia Andrea; Ferreira Parker, Jorge; Ferreira Vigouroux, Luis Arturo (2016)
      Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T. ...
    • Exogenous calreticulin, incorporated onto non-infective Trypanosoma cruzi epimastigotes, promotes their ... 
      Sosoniuk Roche, Eduardo Rodrigo; Vallejos, G.; Aguilar Guzmán, Lorena Andrea; Pizarro Bauerle, Javier; Weinberger, K.; Rosas Chuñil, Carlos; Valck Calderón, Carolina Eliana; Michalak, Marek (2016)
      Chagas disease is an endemic pathology in Latin America, now emerging in developed countries, causedby the intracellular protozoan Trypanosoma cruzi, whose life cycle involves three stages: amastigotes,epimastigotes, and ...
    • The Interactions of Parasite Calreticulin With Initial Complement Components: Consequences in Immunity and ... 
      Ramírez Toloza, Galia; Aguilar Guzmán, Lorena Andrea; Valck, Carolina; Ferreira, Viviana P.; Ferreira, Arturo (Frontiers Media, 2020)
      Because of its capacity to increase a physiologic inflammatory response, to stimulate phagocytosis, to promote cell lysis and to enhance pathogen immunogenicity, the complement system is a crucial component of both the ...
    • Trypanosoma cruzi calreticulin: immune evasion, infectivity, and tumorigenesis 
      Ramírez Toloza, Galia; Sosoniuk Roche, Eduardo; Valck Calderón, Carolina; Aguilar Guzmán, Lorena; Ferreira, Viviana; Ferreira Vigouroux, Luis (Elsevier, 2020)
      To successfully infect, Trypanosome cruzi evades and modulates the host immune response. T. cruzi calreticulin (TcCalr) is a multifunctional, endoplasmic reticulum (ER)-resident chaperone that, translocated to the external ...