Browsing by Author "0330e29e-8114-4683-b12d-5d6edf5128ef"

Now showing items 1-4 of 4

    • Dickkopf-1 reduces hypertrophic changes in human chondrocytes derived from bone marrow stem cells 
      Rojas, Andrea; Mardones, Rodrigo; Pritzker, Kenneth; van Wijnen, Andre J.; Galindo, Mario A.; Las Heras, Facundo (Elsevier B.V., 2019)
      © 2018The in vitro process of chondrogenic differentiation of mesenchymal stem cells (MSCs) induces a pre-apoptotic hypertrophic phenotype, guided by the active status of the WNT/β‑catenin pathway. To achieve a stable ...
    • Regulatory T cell phenotype and anti osteoclastogenic function in experimental periodontitis 
      Álvarez, Carla; Suliman, Salwa; Almarhoumi, Rawan; Vega, María Elena; Rojas, Carolina; Monasterio, Gustavo; Galindo, Mario; Vernal Astudillo, Rolando; Kantarci, Alpdogan (Nature, 2020)
      The alveolar bone resorption is a distinctive feature of periodontitis progression and determinant for tooth loss. Regulatory T lymphocytes (Tregs) display immuno-suppressive mechanisms and tissue repairing functions, which ...
    • SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes 
      Hermosilla, Viviana; Salgado, Ginessa; Riffo, Elizabeth; Escobar, David; Hepp, Matias; Farkas, Carlos; Galindo, Mario; Morín, Violeta; García-Robles, María; Castro, Ariel; Pincheira, Roxana (Wiley, 2018-06)
      SALL2 is a poorly characterized transcription factor that belongs to the Spalt-like family involved in development. Mutations on SALL2 have been associated with ocular coloboma and cancer. In cancers, SALL2 is deregulated ...
    • Sall2 transcription factor: a novel regulator of G1-S cyclins 
      Hermosilla, Viviana E.; Escobar, David E.; Hepp, Matias I.; Riffo, Elizabeth N.; Salgado, Ginessa; Morin, Violeta; Galindo, Mario A.; Castro, Ariel F.; Pincheira, Roxana (Amer Assoc. Cancer Research, 2018-05)