Browsing by Author "072b6179-555f-435b-9484-7483b23fc08d"

Now showing items 1-18 of 18

    • Chronic Chagas cardiopathy in Chile. Importance of Trypanosoma cruzi burden and clinical evaluation 
      Apt Baruch, Werner; Arribada Contreras, Julio; Zulantay Alfaro, Inés; Saavedra, Miguel; Muñoz, Catalina; Toro, Bruno; Vega, Bastián; Rodríguez Tobar, Jorge (Elsevier, 2016)
      Currently there are no biological markers to indicate which individuals with chronic indeterminate period of Chagas disease develop heart disease and who will remain all his life in this phase. The aim of this survey was ...
    • Course of serological tests in treated subjects with chronic Trypanosoma cruzi infection: A systematic ... 
      Sguassero, Yanina; Roberts, Karen N.; Harvey, Guillermina B.; Comandé, Daniel; Ciapponi, Agustín; Cuesta, Cristina B.; Aguiar, Camila; Castro, Ana M. de; Danesi, Emmaria; Andrade, Ana L. de; Lana, Marta de; Escriba, Josep M.; Fabbro, Diana L.; Fernandes, Cloe D.; Flores Chávez, María; Hasslocher Moreno, Alejandro M.; Jackson, Yves; Lacunza, Carlos D.; Machado-de-Assis, Girley F.; Maldonado, Marisel; Meirat, Wendell S. F.; Molinau, Israel; Monje Rumiw, María M.; Muñoz San Martín, Catalina; Murcia, Laura; Castro, Cleudson Nery de; Sánchez Negrette, Olga; Segovia, Manuel; Silveira, Celeste A. N.; Solari Illescas, Aldo; Steindel, Mario; Streigerk, Mirtha L.; Vera de Bilbao, Ninfa; Zulantay Alfaro, Inés; Sosa Estani, Sergio (Elsevier, 2018)
      Objective: To determine the course of serological tests in subjects with chronic Trypanosoma cruzi infection treated with anti-trypanosomal drugs. Methods: A systematic review and meta-analysis was conducted using ...
    • Detection of Trypanosoma cruzi in untreated chronic chagasic patients is improved by using three parasitological ... 
      Zulantay Alfaro, Inés; Apt Baruch, Werner; Valencia, Claudio; Torres, Alberto; Saavedra, Miguel; Sánchez Rodríguez, Jorge E.; Sandoval, Lea; Martínez, Gabriela; Thieme, Patricio; Sepúlveda, Eduardo (2011)
      Objectives: This study compared three parasitological methods applied simultaneously in individuals with untreated chronic Chagas' disease in order to determine their individual and combined performances. Methods: From a ...
    • Differential distribution of Trypanosoma cruzi clones in human chronic chagasic cardiopathic and non-cardiopathic ... 
      Venegas, Juan; Coñoepan, William; Pichuantes, Sergio; Miranda, Sandra; Apt Baruch, Werner; Arribada, Arturo; Zulantay Alfaro, Inés; Coronado, Ximena; Rodriguez, Jorge; Reyes, Eduardo; Solari Illescas, Aldo; Sanchez, Gittith (2009)
      PCR and Southern blot hybridization were used to determine the distribution of Trypanosoma cruzi clones in 37 chronic chagasic cardiopathic and non-cardiopathic patients. Parasite DNA amplified from peripheral blood or ...
    • Discrete typing units of Trypanosoma cruzi detected by real-time PCR in Chilean patients with chronic Chagas ... 
      Muñoz San Martín, Catalina; Zulantay Alfaro, Inés; Saavedra, Miguel; Fuentealba, Cristián; Muñoz, Gabriela; Apt Baruch, Werner (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Chagas disease is a major public health problem in Latin America and has spread to other countries due to immigration of infected persons. 10–30% of patients with chronic Chagas disease will develop ...
    • Enfermedad de Chagas crónica. Ausencia de Triatoma infestans intradomiciliario y persistencia de Trypanosoma ... 
      Zulantay Alfaro, Inés; Bozán, Francisca; Salas, Carlos; Zilleruelo, Nicolás; Osuna, Antonio; Gil, Luis C.; Sánchez Rodríguez, Jorge E.; Rojas, Antonio; Egea, Jose L.; Apt Baruch, Werner (2004)
      In 1999 Chile declare no vectorial transmission of Chagas disease. On the other hand, the development of dwelling policy which include endemic rural zones, have obtained important advances in human groups with height ...
    • Presence of Trypanosoma cruzi in pregnant women and typing of lineages in congenital cases 
      Ortíz, Sylvia; Zulantay Alfaro, Inés; Solari Illescas, Aldo; Bisio, Margarita; Schijman, Alejandro; Carlier, Yves; Apt Baruch, Werner (2012)
      The objective of this study was to determine the presence of Trypanosoma cruzi in blood samples of mothers with chronic Chagas disease and their newborn by conventional PCR targeted to minicircle kinetoplastidic DNA (kDNA), ...
    • Quantification by real-time PCR of Trypanosoma cruzi DNA in samples of Triatoma infestans used in xenodiagnosis ... 
      Saavedra, Miguel; Zulantay Alfaro, Inés; Apt Baruch, Werner; Castillo, Juan; Araya, Eduardo; Martínez, Gabriela; Sánchez Rodríguez, Jorge E. (BioMed Central Ltd., 2016)
      © 2016 The Author(s).Background: Trypanosoma cruzi multiplies and differentiates in the digestive tract of triatomine insects. Xenodiagnosis (XD) is a parasitological tool in which the insect vectors acts as a biological ...
    • Real-Time PCR in faecal samples of Triatoma infestans obtained by xenodiagnosis: Proposal for an exogenous ... 
      Bravo, Nicolás; Mũoz, Catalina; Nazal, Nicolás; Saavedra, Miguel; Martínez, Gabriela; Acha Araya, Eduardo Javier; Apt Baruch, Werner; Zulantay Alfaro, Inés (2012)
      Background: The polymerase chain reaction (PCR) has proved to be a sensitive technique to detect Trypanosoma cruzi in the chronic phase of Chagas disease, which is characterized by low and fluctuating parasitemia. Another ...
    • Real-time PCR strategy for the identification of Trypanosoma cruzi discrete typing units directly in ... 
      Muñoz San Martín, Catalina; Apt Baruch, Werner; Zulantay Alfaro, Inés (Elsevier B.V., 2017)
      © 2017 Elsevier B.V. The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, a major public health problem in Latin America. This parasite has a complex population structure comprised by six or seven major ...
    • T. cruzi oligoC-tesT: A simplified and standardized polymerase chain reaction format for diagnosis of Chagas ... 
      Deborggraeve, Stijn; Coronado, Ximena; Solari Illescas, Aldo; Zulantay Alfaro, Inés; Apt Baruch, Werner; Mertens, Pascal; Laurent, Thierry; Leclipteux, Thierry; Stessens, Tim; Dujardin, Jean Claude; Herdewijn, Piet; Büscher, Philippe (2009)
      Background: PCR has evolved into one of the most promising tools for T. cruzi detection in the diagnosis and control of Chagas disease. However, general use of the technique is hampered by its complexity and the lack of ...
    • The C-terminal region of Trypanosoma cruzi MASPs is antigenic and secreted via exovesicles 
      Miguel De Pablos, Luis; Diaz Lozano, Isabel María; Jercic, María Isabel; Quinzada, Markela; Giménez, María José; Calabuig, Eva; Espino, Ana Margarita; Gabriel Schijman, Alejandro; Zulantay Alfaro, Inés; Apt Baruch, Werner; Osuna, Antonio (Nature Publishing Group, 2016)
      Trypanosoma cruzi is the etiological agent of Chagas disease, a neglected and emerging tropical disease, endemic to South America and present in non-endemic regions due to human migration. The MASP multigene family is ...
    • Transferability of Trypanosoma cruzi from mixed human host infection to Triatoma infestans and from insects ... 
      Ortiz, Sylvia; Zulantay Alfaro, Inés; Apt Baruch, Werner; Saavedra, Miguel; Solari Illescas, Aldo (Elsevier Ireland Ltd, 2015)
      © 2014 Elsevier Ireland Ltd. The etiologic agent of Chagas disease is Trypanosoma cruzi, a protozoan whose life cycle involves obligatory passage through vertebrate and invertebrate hosts in a series of stages. The aim of ...
    • Trypanosoma cruzi burden, genotypes, and clinical evaluation of Chilean patients with chronic Chagas cardiopathy 
      Apt Baruch, Werner; Arribada, Arturo; Zulantay Alfaro, Inés; Saavedra, Miguel; Araya, Eduardo; Solari Illescas, Aldo; Ortiz, Sylvia; Arriagada, Katherine; Sánchez Rodríguez, Jorge E. (Springer Verlag, 2015)
      © 2015, The Author(s).There are currently no biomarkers to assess which patients with chronic indeterminate Chagas disease will develop heart disease and which will spend their entire life in this state. We hypothetize ...
    • The Trypanosoma cruzi Satellite DNA OligoC-TesT and Trypanosoma cruzi Kinetoplast DNA OligoC-TesT for ... 
      De Winne, Koen; Büscher, Philippe; Luquetti, Alejandro O.; Tavares, Suelene B. N.; Oliveira, Rodrigo A.; Solari Illescas, Aldo; Zulantay Alfaro, Inés; Apt Baruch, Werner; Diosque, Patricio; Monje Rumi, Mercedes; Girones, Nuria; Fresno, Manuel; López Vélez, Rogelio; Pérez Molina, José A.; Monge Maillo, Begoña; García, Lineth; Deborggraeve, Stijn (2014)
      Background: The Trypanosoma cruzi satellite DNA (satDNA) OligoC-TesT is a standardised PCR format for diagnosis of Chagas disease. The sensitivity of the test is lower for discrete typing unit (DTU) TcI than for TcII-VI ...
    • Use of polymerase chain reaction (PCR) and hybridization assays to detect trypanosoma cruzi in chronic ... 
      Zulantay Alfaro, Inés; Honores, Patricia; Solari Illescas, Aldo; Apt Baruch, Werner; Ortíz, Sylvia; Osuna, Antonio; Rojas, Antonio; López, Bernardo; Sánchez, Gittith (2004)
      The presence of Trypanosoma cruzi in chronic chagasic patients with negative xenodiagnosis (XD) after 6 years following completion of therapy with either itraconazole or allopurinol was assessed by polymerase chain reaction ...
    • Vertical transmission of trypanosoma cruzi in the province of Choapa, IV region, Chile. preliminary report ... 
      Apt Baruch, Werner; Zulantay Alfaro, Inés; Solari Illescas, Aldo; Ortiz, Sylvia; Oddo, David; Corral, Gabriela; Truyens, Carine; Carlier, Yves (Society of Biology of Chile, 2010)
      Congenital Chagas disease acquired special importance in Chile after the certification of the control of Triatoma infestans and transmission by blood donors affected with Trypanosoma cruzi. In order to establish adequate ...
    • What do the numbers tell us about the temporal evolution of Chagas’ disease? ¿Qué dicen los números de la ... 
      Canals Lambarri, Mauricio; Yáñez González, Christian Ariel; Canals, Lucía; Canals Cifuentes, Andrea; Cáceres, Dante; Alvarado, Sergio A.; Cattan Ayala, Pedro; Saavedra, Miguel; Zulantay Alfaro, Inés; Apt Baruch, Werner (Sociedad Chilena de Infectologia, 2017)
      ©, 2017 Sociedad Chilena de Infectologia. All rights reserved.Chagas disease remains highly prevalent in Chile, especially between the regions of Arica and Parinacota, and Coquimbo. Since 1999 it is considered that in Chile ...