Browsing by Author "09e7673f-20f0-4c09-88e1-d89531c9e470"
Now showing items 1-7 of 7
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Hidalgo, Miltha; Rodríguez, Vania; Kreindl, Christine; Porras Espinoza, Omar (MDPI, 2020)Most of the biological impacts of Vitamin E, including the redox effects, have been raised from studies with alpha-tocopherol only, despite the fact that tocopherol-containing foods carry mixed tocopherol isomers. Here, ...
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Kallens, Violeta; Tobar Bachler, Nicolás; Molina, Jessica; Bidegain, Arantzazú; Smith, Patricio C.; Porras Espinoza, Omar; Martínez, Jorge (Wiley, 2017)Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...
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Carrasco-Wong, Ivo; Hernández, Cherie; Jara-Gutiérrez, Carlos; Porras Espinoza, Omar; Casanello, Paola (Wiley-Liss Inc., 2019)Obesity is a public health problem worldwide, and especially in women in reproductive age where more than one in three have obesity. Maternal obesity is associated with an increased maternal, placental, and newborn oxidative ...
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Núñez-Villena, Felipe; Becerra, Alvaro; Echeverría, Cesar; Briceño, Nicolás; Porras Espinoza, Omar; Armisen Yáñez, Ricardo; Varela, Diego; Montorfano, Ignacio; Sarmiento, Daniela; Simon, Felipe (2011)Aims: To assess the mechanisms involved in lipopolysaccharide (LPS)-induced neuronal cell death, we examined the cellular consequences of LPS exposure in differentiated PC12 neurons and primary hippocampal neurons. Results: ...
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Bernal Sore, Izela; Navarro Márquez, Mario F.; Osorio Fuentealba, César; Díaz Castro, Francisco; Campo, Andrea del; Donoso Barraza, Camila; Porras Espinoza, Omar; Lavandero González, Sergio; Troncoso Cotal, Rodrigo (Elsevier, 2018)Mifepristone is the only FDA-approved drug for glycaemia control in patients with Cushing's syndrome and type 2 diabetes. Mifepristone also has beneficial effects in animal models of diabetes and patients with antipsychotic ...
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Tobar Bachler, Nicolás; Porras Espinoza, Omar; Smith, Patricio C.; Barros, L. Felipe; Martínez, Jorge (Wiley, 2017)Hyperglycemia is a risk factor for a variety of human cancers. Increased access to glucose and that tumor metabolize glucose by a glycolyticprocess even in the presence of oxygen (Warburg effect), provide a framework to ...
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Román, Flavia; Urra, Carla; Porras Espinoza, Omar; Pino, Ana María; Rosen, Clifford J.; Rodríguez, Juan Pablo (Wiley-Liss Inc., 2017)© 2016 Wiley Periodicals, Inc. Oxidative stress (OS) derived from an increase in intracellular reactive oxygen species (ROS) is a major determinant of aging and lifespan. It has also been associated with several age-related ...