Browsing by Author "0a9852b0-b4e8-4571-a5f2-3fc57eaa7902"

Now showing items 1-4 of 4

    • Calcium channel subtypes differentially regulate fusion pore stability and expansion 
      Ardiles, Alvaro O.; González-Jamett, Arlek M.; Maripillán, Jaime; Naranjo, David; Caviedes, Pablo; Cárdenas, Ana María (2007)
      Various studies have focused in the relative contribution of different voltage-activated Ca2+ channels (VACC) to total transmitter release. However, how Ca2+ entry through a given VACC subtype defines the pattern of ...
    • IRE1 signaling exacerbates Alzheimer's disease pathogenesis 
      Durán Aniotz, Claudia; Cornejo, Victor Hugo; Espinoza, Sandra; Ardiles, Alvaro O.; Medinas Bilches, Danilo; Salazar, Claudia; Foley, Andrew; Gajardo, Ivana; Thielen, Peter; Iwawaki, Takao; Scheper, Wiep; Soto, Claudio; Palacios, Adrian G.; Hoozemans, Jeroen J. M.; Hetz Flores, Claudio (Springer, 2017)
      Altered proteostasis is a salient feature of Alzheimer's disease (AD), highlighting the occurrence of endoplasmic reticulum (ER) stress and abnormal protein aggregation. ER stress triggers the activation of the unfolded ...
    • Lack of pannexin 1 alters synaptic GluN2 subunit composition and spatial reversal learning in mice 
      Gajardo, Ivana; Salazar, Claudia S.; López Espindola, Daniela; Estay, Carolina; Flores Muñoz, Carolina; Elgueta, Claudio; González Jamett, Arlek M.; Martinez, Agustin D.; Muñoz, Pablo; Ardiles, Alvaro O. (Frontiers media SA, 2018)
      Long-term potentiation (LTP) and long-term depression (LTD) are two forms of synaptic plasticity that have been considered as the cellular substrate of memory formation. Although LTP has received considerable more attention, ...
    • Role of Tau Protein in Neuronal Damage in Alzheimer's Disease and Down Syndrome 
      Cárdenas, Ana María; Ardiles, Álvaro O.; Barraza, Natalia; Báez Matus, Ximena; Caviedes, Pablo (Elsevier, 2012)
      Neurodegenerative disorders constitute a growing concern worldwide. Their incidence has increased steadily, in particular among the elderly, a high-risk population that is becoming an important segment of society. ...