Browsing by Author "0b5b9ec8-58f5-4851-90d9-e9a1d304dd8c"

Now showing items 1-4 of 4

    • Complex mitochondrial dysfunction induced by TPP+-gentisic acid and mitochondrial translation inhibition ... 
      Fuentes Retamal, Sebastián; Sandoval Acuña, Cristian; Peredo Silva, Liliana; Guzmán Rivera, Daniela; Pavani, Mario; Torrealba, Natalia; Truksa, Jaroslav; Castro Castillo, Vicente; Catalán Díaz, Mabel; Kemmerling Weis, Ulrike; Urra Faúndez, Félix; Ferreira, Jorge (MDPI, 2020)
      The mitochondrion has emerged as a promising therapeutic target for novel cancer treatments because of its essential role in tumorigenesis and resistance to chemotherapy. Previously, we described a natural compound, ...
    • Destabilization of mitochondrial functions as a target against breast cancer progression: Role of ... 
      Sandoval Acuña, Cristian; Fuentes Retamal, Sebastián; Guzmán Rivera, Daniela; Peredo Silva, Liliana; Madrid Rojas, Matías; Rebolledo, Solange; Castro Castillo, Vicente; Pavani, Mario; Catalán, Mabel; Maya Arango, Juan; Jara, Jose A.; Parra, Eduardo; Calaf, Gloria M.; Speisky Cosoy, Hernán; Ferreira Parker, Jorge (2016)
      Mitochondrion is an accepted molecular target in cancer treatment since it exhibits a higher transmembrane potential in cancer cells, making it susceptible to be targeted by lipophilic-delocalized cations of triphenylphosphonium ...
    • Notch receptor expression in Trypanosoma cruzi‐infected human umbilical vein endothelial cells treated with ... 
      Campos Estrada, Carolina; González Herrera, Fabiola; Greif, Gonzalo; Carrillo Werner, Ileana; Guzmán Rivera, Daniela; Liempi Manquel, Ana; Robello, Carlos; Kemmerling Weis, Ulrike; Castillo Rivas, Christian; Maya Arango, Juan Diego (Wiley, 2020)
      Chagas disease is a vector-borne disease caused by the protozoan parasite Trypanosoma cruzi. Current therapy involves benznidazole. Benznidazole and other drugs can modify gene expression patterns, improving the response ...
    • Simvastatin improves cardiac function through Notch 1 activation in BALB/c mice with Chronic Chagas Cardiomyopathy 
      Guzmán Rivera, Daniela; Liempi Manquel, Ana; González Herrera, Fabiola; Fuentes Retamal, Sebastián; Carrillo, Ileana; Abarca Bustos, Patricio; Castillo Rivas, Christian; Kemmerling Weis, Ulrike; Pesce Reyes, Bárbara; Maya Arango, Juan Diego (American Society for Microbiology (ASM), 2020)
      Chagas disease, caused by the protozoan Trypanosome cruzi, endemic in Latin America but distributed worldwide because of migration. Without appropriate treatment, the disease progresses from an acute asymptomatic phase to ...