Browsing by Author "0be6b0f0-1828-4e34-9150-ba68f861a0f9"

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    • Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2 
      Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
    • Intranasal administration of gold nanoparticles designed to target the central nervous system: Fabrication ... 
      Gallardo Toledo, Eduardo; Tapia Arellano, Andreas; Celis, Freddy; Sinai, Tomer; Campos, Marcelo; Kogan, Marcelo J.; Sintov, Amnon C. (Elsevier, 2020)
      The presence of the blood-brain barrier (BBB) limit gold nanoparticles (GNP) accumulation in central nervous system (CNS) after intravenous (IV) administration. The intranasal (IN) route has been suggested as a good strategy ...