Browsing by Author "13c48458-33e7-4b9f-92b3-e4763c9c72c3"
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Osorio, Fabiola; Lambrecht, Bart; Janssens, Sophie (Elsevier, 2018-06)The unfolded protein response (UPR) is an adaptive response meant to restore endoplasmic reticulum homeostasis in conditions of ER stress that subvert the folding capacity of the cell. Over the past few years, it has become ...
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Medel, Bernardita; Costoya, Cristobal; Fernandez, Dominique; Pereda, Cristian; Lladser, Alvaro; Sauma, Daniela; Pacheco, Rodrigo; Iwawaki, Takao; Salazar Onfray, Flavio; Osorio, Fabiola (Frontiers Media S.A., 2019)The IRE1α/XBP1s signaling pathway is an arm of the unfolded protein response (UPR) that safeguards the fidelity of the cellular proteome during endoplasmic reticulum (ER) stress, and that has also emerged as a key regulator ...