Now showing items 1-4 of 4

    • Norambuena Soto, Ignacio; Ocaranza, María Paz; Cancino Arenas, Nicole; Sanhueza Olivares, Fernanda; Villar Fincheira, Paulina; Leiva Navarrete, Sebastián; Mancilla Medina, Cristian; Moya, Jacqueline; Novoa, Ulises; Jalil, Jorge E.; Castro, Pablo F.; Lavandero González, Sergio; Chiong Lay, Mario (Pergamon-Elsevier Science, 2020)
      The renin-angiotensin system, one of the main regulators of vascular function, controls vasoconstriction, inflammation and vascular remodeling. Antagonistic actions of the counter-regulatory renin-angiotensin system, which ...
    • García Miguel, Marina; Riquelme, Jaime A.; Norambuena Soto, Ignacio; Morales, Pablo E.; Sanhueza Olivares, Fernanda; Núñez Soto, Constanza Belén; Mondaca Ruff, David; Cancino Arenas, Nicole; San Martín, Alejandra; Chiong Lay, Mario (Public library science, 2018-05-11)
      Vascular smooth muscle cells (VSMC) dedifferentiation from a contractile to a synthetic phenotype contributes to atherosclerosis. Atherosclerotic tissue has a chronic inflammatory component with high levels of tumor necrosis ...
    • Villar Fincheira, Paulina; Sanhueza Olivares, Fernanda; Norambuena Soto, Ignacio; Cancino Arenas, Nicole; Hernández Vargas, Felipe; Troncoso Cotal, Rodrigo; Gabrielli, Luigi; Chiong Lay, Mario (Frontiers Media, 2021)
      IL-6 is usually described as a pleiotropic cytokine produced in response to tissue injury or infection. As a pro-inflammatory cytokine, IL-6 activates innate and adaptative immune responses. IL-6 is released in the innate ...
    • Norambuena Soto, Ignacio; Núñez Soto, Constanza; Sanhueza Olivares, Fernanda; Cancino Arenas, Nicole; Mondaca Ruff, David; Vivar Sánchez, Raúl; Díaz Araya, Guillermo; Mellado, Rosemarie; Chiong Lay, Mario (IRCA-BSSA, 2017)
      Fibroblasts play several homeostatic roles, including electrical coupling, paracrine signaling and tissue repair after injury. Fibroblasts have low secretory activity. However, in response to injury, they differentiate to ...