Browsing by Author "15f9e7d1-0127-4c14-9904-84b20a5540da"

Now showing items 1-4 of 4

    • In Vitro Inhibition of Helicobacter pylori Growth by Redox Cycling Phenylaminojuglones 
      Benites, Julio; Toledo, Héctor; Salas, Felipe; Guerrero, Angélica; Rios, David; Valderrama, Jaime A.; Calderon, Pedro Buc (2018)
      Infection by Helicobacter pylori increases 10 times the risk of developing gastric cancer. Juglone, a natural occurring 1,4-naphthoquinone, prevents H. pylori growth by interfering with some of its critical metabolic ...
    • Inhibition of cancer cell growth and migration by dihydroxynaphthyl aryl ketones 
      Benites, Julio; Valderrama, Jaime A.; Ríos, David; Lagos Mónaco, Rosalba; Monasterio Opazo, Octavio; Buc Calderón, Pedro (2016)
      Dihydroxynaphthyl aryl ketones 1-5 exhibit activity as tubulin polymerization inhibitors by targeting the colchicine binding site of microtubules making them potential anticancer drugs. Therefore, analogues 1-5 have been ...
    • Metabolomic analysis of the lichen everniopsis trulla using ultra high performance liquid Chromatography- ... 
      Castro, Olivio N.; Benites, Julio; Rodilla, Jesús; Santiago, Julio C.; Simirgiotis, Mario J.; Sepúlveda, Beatriz; Areche Medina, Carlos (Springer, 2017-06)
      A new depside was identified in the methanolic extract from the lichen Everniopsis trulla based on the metabolomics UHPLC-DAD-MS analysis and HESI-MS-MS fragmentation patterns along with thirty-two known compounds for the ...
    • Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta 
      Palacios, Javier; Cifuentes, Fredi; Valderrama, Jaime A.; Benites, Julio; Ríos, David; González, Constanza; Chiong Lay, Mario; Cartes Saavedra, Benjamín; Lafourcade, Carlos; Wyneken, Úrsula (2016)
      The vascular endotheliumplays an essential role in the control of the blood flow. Pharmacological agents like quinone (menadione) at various doses modulate this process in a variety of ways. In this study, Q7, a ...