Browsing by Author "19eba4d7-255e-4a42-8779-481819cf7177"

Now showing items 1-5 of 5

    • Ca(v)1.2 Activity and Downstream Signaling Pathways in the Hippocampus of An Animal Model of Depression 
      Moreno, Cristian; Hermosilla, Tamara; Hardy, Paulina; Aballai, Víctor; Rojas, Patricio; Varela Lekanda, Diego (MDPI, 2020)
      Functional and morphological modifications in the brain caused by major mood disorders involve many brain areas, including the hippocampus, leading to cognitive and mood alterations. Ca(v)1.2 channel expression has been ...
    • Cavβ2 transcription start site variants modulate calcium handling in newborn rat cardiomyocytes 
      Moreno, Cristian; Hermosilla, Tamara; Morales, Danna; Encina, Matías; Torres-Díaz, Leandro; Díaz, Pablo; Sarmiento, Daniela; Simon, Felipe; Varela, Diego (Springer Verlag, 2015)
      © 2015, Springer-Verlag Berlin Heidelberg.In the heart, the main pathway for calcium influx is mediated by L-type calcium channels, a multi-subunit complex composed of the pore-forming subunit CaV1.2 and the auxiliary ...
    • Immunoglobulins concentration and B cell counts as severity markers in adult community-acquired pneumonia ... 
      Luchsinger, Vivian; Lizama, Luis; Garmendia, María Luisa; Tempio, Fabián; Ruiz, Mauricio; Pizarro, Rolando; Rossi, Patricio; Huenchur, Lucía; Moreno, Cristian; López, Mercedes; Ampuero, Sandra; Larrañaga, Carmen; Avendaño, Luis Fidel (Lippincott Williams & Wilkins, 2020)
      Community-acquired pneumonia (CAP) is a worldwide cause of morbidity and mortality. Immunoglobulins (Igs) and B cells quantification studies in CAP are few and show discrepancies. Serum IgA acts as a powerful natural ...
    • L-type calcium channel β subunit modulates angiotensin II responses in cardiomyocytes 
      Hermosilla, Tamara; Moreno, Cristian; Itfinca, Mircea; Altier, Christophe; Armisen Yáñez, Ricardo; Stutzin Schottlander, Andrés; Zamponi, Gerald W.; Varela, Diego (Taylor and Francis Inc., 2011)
      Angiotensin II regulation of L-type calcium currents in cardiac muscle is controversial and the underlying signaling events are not completely understood. Moreover, the possible role of auxiliary subunit composition of the ...
    • Prolonged AT(1)R activation induces Ca(V)1.2 channel internalization in rat cardiomyocytes 
      Hermosilla, Tamara; Encina, Matías; Morales, Danna; Moreno, Cristian; Conejeros, Carolina; Alfaro Valdés, Hilda M.; Lagos Meza, Felipe; Simon, Felipe; Altier, Christophe; Varela, Diego (Nature Publishing Group, 2017)
      The cardiac L-type calcium channel is a multi-subunit complex that requires co-assembling of the pore-forming subunit Ca(V)1.2 with auxiliary subunits Ca-V alpha 2 delta and Ca-V beta. Its traffic has been shown to be ...