Now showing items 1-14 of 14

    • Bórquez, Jorge; Molina Salinas, Gloria María; Loyola, Luis Alberto; San Martín Barrientos, Aurelio; Peña Rodríguez, Luis Manuel; Said Fernández, Salvador (2011)
      A new azorellane diterpenoid has been isolated and identified from the aerial parts of Azorella madreporica Clos. The structure of 1 was established by one- and two-dimensional NMR techniques. © 2011 Taylor & Francis.
    • Bórquez, Jorge; Loyola, Luis A.; Morales, Glauco; San Martín Barrientos, Aurelio; Roldan, Raquel; Marquez, Nieves; Muñoz, Eduardo (2007)
      Transcription factor NF-κB plays a key role in the inducible expression of genes mediating proinflammatory effects, and is thus an important target for the development of antiinflammatory drugs. Laretia acaulis (Cav.) Gill ...
    • Loyola, Luis Alberto; Bórquez, Jorge; Morales, Glauco; San Martín Barrientos, Aurelio; Manríquez, Víctor; Wittke, Oscar (Elsevier Ltd, 1998)
      A new diterpenoid, azorellanol (5), was isolated from the whole plant of Azorella compacta (Umbelliferae). The stricture was established by using mainly one- and two-dimensional NMR techniques, whereas the absolute ...
    • Areche Medina, Carlos; Hernández, Marco; Cano, Teresa; Ticona, Juana; Cortes, Carmen; Simirgiotis, Mario; Cáceres, Fátima; Bórquez, Jorge; Echeverría, Javier; Sepúlveda, Beatriz (Frontiers Media, 2020)
      Corryocactus brevistylus (K. Schum. ex Vaupel) Britton & Rose (Cactaceae) is a shrubby or often arborescent cactus popularly known as "sancayo" and produce an edible fruit known as "Sanky" which is consumed in Arequipa-Peru. ...
    • Loyola, Luis A.; Bórquez, Jorge; Morales, Glauco; San Martín Barrientos, Aurelio (1997)
      In addition to mulinolic acid, a new diterpenoid, mulin-11,13-dien-20- oic acid, has been isolated from the aerial parts of Azorella compacta. Its structure was based on a spectroscopic comparison with mulinolic acid and ...
    • Loyola, Luis A.; Bórquez, Jorge; Morales, Glauco; Araya, Jorge; González, Jorge; Neira, Ivan; Sagua, Hernan; San Martín Barrientos, Aurelio (2001)
      Diterpenoids with trichomonicidal activity were isolated from the aerial parts of Azorella yareta Hauman. One was 13β-hydroxyazorellane, together with the known constituents mulinolic acid, mulin-11,13-dien-20-oic acid, ...
    • Ardiles, Alejandro; Barrientos, Ruth; Simirgiotis, Mario J.; Bórquez, Jorge; Sepúlveda, Beatriz; Areche, Carlos (MDPI AG, 2018)
      © 2018 MDPI AG. All rights reserved. Forty-three metabolites including several methoxylated flavonoids, tremetones, and ent-clerodane diterpenes were accurately identified for the first time in the ethanolic extract of P. ...
    • Rodríguez, Stephanie; Walter Pertino, Mariano; Arcos, Chantal; Reichert, Luana; Echeverría, Javier; Simirgiotis, Mario; Bórquez, Jorge; Cornejo, Alberto; Areche Medina, Carlos; Sepúlveda, Beatriz (MDPI, 2020)
      Lycium minutifoliumJ. Remy (Solanaceae) is commonly used as an infusion in traditional medicine to treat stomach pain, meteorism, intestinal disorders, stomach ailments, and other severe problems including prostate cancer ...
    • Loyola, Luis Alberto; Bórquez, Jorge; Morales, Glauco; San Martín Barrientos, Aurelio; Darias, José (2002)
      A unique diterpene 1, was isolated from the altiplane Andean plant Azorella madreporica Clos (Apiaceae). The structure and stereochemistry were established by spectral methods and molecular mechanics calculations. The ...
    • Loyola, Luis A.; Bórquez, Jorge; Morales, Glauco; San Martín Barrientos, Aurelio; Darias, Jose; Flores, Ninoska; Giménez, Alberto (2004)
      Two mulinane-type diterpenoids were isolated from Azorella compacta; namely 20-hydroxymulin-11,13-dienyl acetate and 13,14-dihydroxymulin-11-en-20-oic acid. The structures were elucidated by analysis of their spectroscopic ...
    • Loyola, Luis A.; Bórquez, Jorge; Morales, Glauco; San Martín Barrientos, Aurelio (2000)
      In addition to the known mulinolic acid and mulin-11, 13-dien-20-oic acid, 13-epimulinolic acid has been isolated from the aerial parts of Laretia acaulis (Cav.) Gill et Hook (Umbelliferae). Its structure was based on ...
    • Simirgiotis, Mario J.; Quispe, Cristina; Mocan, Andrei; Villatoro, José Miguel; Areche, Carlos; Bórquez, Jorge; Sepúlveda, Beatriz; Echiburu-Chau, Carlos (Sociedade Brasileira de Farmacognosia, 2017)
      © 2016 Sociedade Brasileira de Farmacognosia. High-resolution mass spectrometry is currently used to determine the mass of biologically active compounds in plants and UHPLC-Orbitrap is a relatively new technology that ...
    • Jiménez-González, Andrea; Quispe, Cristina; Bórquez, Jorge; Sepúlveda, Beatriz; Riveros, Felipe; Areche, Carlos; Nagles, Edgar; García Beltrán, Olimpo; Simirgiotis, Mario J. (Taylor & Francis, 2018)
      UHPLC/ESI/MS identification of organic compounds is the first step in the majority of screening techniques for the characterization of biologically active metabolites in natural sources. This paper describes a method for ...
    • Jiménez-González, Andrea; Quispe, Cristina; Bórquez, Jorge; Sepúlveda, Beatriz; Riveros, Felipe; Areche, Carlos; Nagles, Edgar; García Beltrán, Olimpo; Simirgiotis, Mario J. (Taylor and Francis Ltd, 2018)
      © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. UHPLC/ESI/MS identification of organic compounds is the first step in the majority of screening techniques for the characterization ...