Browsing by Author "1d8f3eeb-b5dc-4354-92af-1206a99368a1"

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    • IRE1 signaling exacerbates Alzheimer's disease pathogenesis 
      Durán Aniotz, Claudia; Cornejo, Victor Hugo; Espinoza, Sandra; Ardiles, Alvaro O.; Medinas Bilches, Danilo; Salazar, Claudia; Foley, Andrew; Gajardo, Ivana; Thielen, Peter; Iwawaki, Takao; Scheper, Wiep; Soto, Claudio; Palacios, Adrian G.; Hoozemans, Jeroen J. M.; Hetz Flores, Claudio (Springer, 2017)
      Altered proteostasis is a salient feature of Alzheimer's disease (AD), highlighting the occurrence of endoplasmic reticulum (ER) stress and abnormal protein aggregation. ER stress triggers the activation of the unfolded ...
    • The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease 
      Oñate, Maritza; Catenaccio, Alejandra; Salvadores, Natalia; Saquel, Cristian; Martínez Rojas, Luis; Moreno González, Inés; Gamez, Nazaret; Soto, Paulina; Soto, Claudio; Hetz Flores, Claudio; Court, Felipe A. (Nature Publishing Group, 2020)