Browsing by Author "1e0b3781-6a6a-401e-89da-c6f9e252b76d"

Now showing items 1-6 of 6

    • Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and ... 
      Vivar, Raúl; Humeres, Claudio; Varela, Marcelo; Ayala, Pedro; Guzmán, Nancy; Olmedo, Ivonne; Catalán, Mabel; Boza Fuentes, Pía; Muñoz, Claudia; Díaz Araya, Guillermo (2012)
      Cardiac fibroblast (CF) death by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. Although IGF-1 has well-known cytoprotective effects, no study has been done on CF subjected to simulated ...
    • Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast 
      Catalán, Mabel; Smolic, Christian; Contreras, Ariel; Ayala, Pedro; Olmedo, Ivonne; Copaja, Miguel; Boza Fuentes, Pía; Vivar, Raúl; Avalos, Yennifer; Lavandero González, Sergio; Velarde, Victoria; Díaz Araya, Guillermo (2012)
      Kinins mediate their cellular effects through B1 (B1R) and B2 (B2R) receptors, and the activation of B2R reduces collagen synthesis in cardiac fibroblasts (CF). However, the question of whether B1R and/or B2R have a role ...
    • Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: ... 
      Boza Fuentes, Pía; Ayala, Pedro; Vivar Sánchez, Raúl; Humeres Martínez, Claudio; Tapia Cáceres, Felipe; Muñoz, Claudia; García Nannig, Lorena; Hermoso Ramello, Marcela; Díaz Araya, Guillermo (Elsevier, 2016)
      Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead cells after cardiac ...
    • FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation 
      Vivar, Raúl; Humeres, Claudio; Muñoz, Claudia; Boza Fuentes, Pía; Bolivar, Samir; Tapia, Felipe; Lavandero González, Sergio; Chiong Lay, Mario; Díaz Araya, Guillermo (Elsevier, 2016)
      © 2015 Elsevier B.V. Cardiac fibroblast differentiation to myofibroblast is a crucial process in the development of cardiac fibrosis and is tightly dependent on transforming growth factor beta-1 (TGF-β1). The transcription ...
    • Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression 
      Olivares Silva, Francisco Javier; Landaeta, Rodolfo; Aránguiz, Pablo; Bolivar, Samir; Humeres Martínez, Claudio; Anfossi, Renatto; Vivar Sánchez, Raúl; Boza Fuentes, Pía; Muñoz Jofré, Claudia; Pardo Jiménez, Viviana Gladys; Peiro, Concepción; Sánchez Ferrer, Carlos; Díaz Araya, Guillermo (Elsevier, 2018)
      Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the ...
    • Lipopolysaccharide activates toll like receptor 4 and prevents cardiac fibroblast to myofibroblast differentiation 
      Bolivar, Samir; Santana, Roxana; Ayala, Pedro; Landaeta, Rodolfo; Boza Fuentes, Pía; Humeres Martínez, Claudio; Vivar Sánchez, Raúl; Muñoz Jofré, Claudia; Pardo, Viviana; Fernández, Samuel; Anfossi, Renatto; Díaz Araya, Guillermo (Springer, 2017)
      Bacterial lipopolysaccharide (LPS) is a known ligand of Toll-like receptor 4 (TLR4) which is expressed in cardiac fibroblasts (CF). Differentiation of CF to cardiac myofibroblasts (CMF) is induced by transforming growth ...