Browsing by Author "201-0010797"

Now showing items 1-12 of 12

    • Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano 
      Herrera Videla, Emilio; Reyes, Roberto V.; Giussani, Dino A.; Riquelme González, Raquel; Sanhueza Reinoso, Emilia; Ebensperger Darrouy, Germán; Casanello, Paola; Méndez, Natalia; Ebensperger, Renato; Sepúlveda Kattan, Esteban; Pulgar, Víctor M.; Cabello, Gertrudis; Blanco, Carlos E.; Hanson, Mark A.; Parer, Julian T.; Llanos Mansilla, Jorge (European Society of Cardiology, 2008)
      Aims To study the nitric oxide (NO) and carbon monoxide roles in the regulation of the pulmonary circulation in lowland and highland newborn sheep and llamas. Methods and results We used neonatal sheep (Ovis aries) and ...
    • Evolving in thin air—Lessons from the llama fetus in the altiplano 
      Llanos Mansilla, Jorge; Riquelme González, Raquel; Herrera Videla, Emilio; Ebensperger Darrouy, Germán; Krause, Bernardo; Reyes, Roberto V.; Sanhueza Reinoso, Emilia; Pulgar, Víctor M.; Behn Thiele, Claus; Cabello, Gertrudis; Parer, Julian T.; Giussani, Dino A.; Blanco, Carlos E.; Hanson, Mark A. (ELSEVIER, 2007)
      Compared with lowland species, fetal life for mammalian species whose mothers live in high altitude is demanding. For instance, fetal llamas have to cope with the lowfetal arterial PO2 of all species, but also the likely ...
    • Fetal and postnatal pulmonary circulation in the Alto Andino 
      Llanos Mansilla, Jorge; Ebensperger Darrouy, Germán; Herrera Videla, Emilio; Reyes, R. V.; Pulgar, V. M.; Serón Ferré, María; Díaz Beneventi, Mauricio; Parer, J. T.; Giussani, Dino A.; Moraga, F. A.; Riquelme González, Raquel (Elsevier, 2011)
      Lowland mammals at high altitude constrict the pulmonary vessels, augmenting vascular resistance and developing pulmonary arterial hypertension. In contrast, highland mammals, like the llama, do not present pulmonary ...
    • Fetal brain hypometabolism during prolonged hypoxaemia in the llama 
      Ebensperger Darrouy, Germán; Ebensperger, Renato; Herrera Videla, Emilio; Riquelme González, Raquel; Sanhueza Reinoso, Emilia; Lesage, Florian; Marengo, Juan José; Tejo, Rodrigo; Llanos Mansilla, Jorge; Reyes, Roberto (BLACKWELL PUBLISHING, 2005-09-15)
      In this study we looked for additional evidence to support the hypothesis that fetal llama reacts to hypoxaemia with adaptive brain hypometabolism. We determined fetal llama brain temperature, Na+ and K+ channel density ...
    • High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep 
      Herrera Videla, Emilio; Pulgar, Víctor M.; Riquelme González, Raquel; Sanhueza Reinoso, Emilia; Reyes, Roberto V.; Ebensperger Darrouy, Germán; Parer, Julian T.; Valdéz, Enrique A.; Giussani, Dino A.; Blanco, Carlos E.; Hanson, Mark A.; Llanos Mansilla, Jorge (AMER PHYSIOLOGICAL SOC, 2007-06)
      Perinatal exposure to chronic hypoxia induces sustained pulmonary hypertension and structural and functional changes in both pulmonary and systemic vascular beds. The aim of this study was to analyze consequences of ...
    • Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in ... 
      Sánchez, G.; Liberona, Leonel; Llanos Mansilla, Jorge; Sanhueza, E. M.; Giussani, Dino A.; Blanco, C. E.; Hanson, M. A.; Riquelme González, Raquel (CAMBRIDGE UNIV PRESS, 2002-10-01)
      The hypothesis that nitric oxide plays a key role in the regulation of adrenal blood flow and plasma concentrations of cortisol and catecholamines under basal and hypoxaemic conditions in the llama fetus was tested. At ...
    • Nitric oxide synthase activity in brain tissues from llama fetuses submitted to hypoxemia 
      Galleguillos, Marco; Valenzuela Pedevila, María Antonieta; Riquelme González, Raquel; Sanhueza, Emilia M.; Sánchez, Gina; Figueroa, Jorge P.; Llanos Mansilla, Jorge (ELSEVIER SCIENCE INC, 2001-06)
      The fetal llama (Lama glama; a species adapted to live in chronic hypoxia in the highlands of the Andes) did not increase cerebral blood flow and reduce the brain oxygen uptake during hypoxemia. Although nitric oxide (NO) ...
    • Respuesta cardiopulmonar a cambios de oxigenación en recién nacidos de ovejas de diferentes altitudes 
      Herrera Videla, Emilio; Ebensperger Darrouy, Germán; Riquelme González, Raquel; Díaz Navarrete, Marcela; Reyes Catalán, Víctor; Torres Farfán, Claudia; Llanos Mansilla, Jorge (Universidad de Chile, 2011)
      La exposición a la hipoxia crónica en el altiplano andino durante el período perinatal induce hipertensión pulmonar y cambios estructurales y funcionales en la circulación pulmonar y sistémica. El objetivo de este estudio ...
    • Sildenafil Reverses Hypoxic Pulmonary Hypertension in Highland and Lowland Newborn Sheep 
      Herrera Videla, Emilio; Ebensperger Darrouy, Germán; Krause, Bernardo; Riquelme González, Raquel; Reyes, Roberto V.; Capetillo, María; González, Sergio; Parer, Julian T.; Llanos Mansilla, Jorge (International Pediatric Research Foundation, Inc., 2008)
      Perinatal exposure to chronic hypoxia induces sustained hypertension and structural and functional changes in the pulmonary vascular bed. We hypothesized that highland newborn lambs (HLNB, 3600 m) have a higher pulmonary ...
    • Store-operated channels in the pulmonary circulation of high- and low-altitude neonatal lambs 
      Parrau, Daniela; Ebensperger Darrouy, Germán; Herrera Videla, Emilio; Moraga, Fernando; Riquelme González, Raquel; Ulloa, César E.; Rojas, Rodrigo T.; Silva, Pablo; Hernández, Ismael; Ferrada, Javiera; Díaz Navarrete, Marcela; Parer, Marcela; Cabello, Gertrudis; Llanos Mansilla, Jorge; Reyes, Roberto V. (the American Physiological Society, 2013)
    • Use of fetal biometry to determine fetal age in late pregnancy in llamas 
      Herrera Videla, Emilio; Riquelme González, Raquel; Sanhueza, E. M.; Raggi Saini, Luis; Llanos Mansilla, Jorge (ELSEVIER SCIENCE BV, 2002-11-15)
      Sixty-three pregnant llamas of known breeding date were used in this study. Forty-six of them were submitted to surgery between 186 and 320 days of gestation (52-91% of average gestation period, respectively). Under general ...
    • Vasodilator tone in the llama fetus: the role of nitric oxide during normoxemia and hypoxemia 
      Sanhueza Reinoso, Emilia; Riquelme González, Raquel; Herrera Videla, Emilio; Giussani, Dino A.; Blanco, Carlos E.; Hanson, Mark A.; Llanos Mansilla, Jorge (AMER PHYSIOLOGICAL SOC, 2005-09)
      The fetal llama responds to hypoxemia, with a marked peripheral vasoconstriction but, unlike the sheep, with little or no increase in cerebral blood flow. We tested the hypothesis that the role of nitric oxide (NO) may be ...