Browsing by Author "201-0098721"
Now showing items 1-12 of 12
-
Pacheco Fuentes, Héctor Arturo (Universidad de Chile, 2013)El control de la transcripción génica en tejido neural y no neural, permite que los genes que codifican para proteínas de expresión exclusiva, se expresen de ésta forma. En el caso de genes de expresión neuronal-específica, ...
-
Bachmann, André; Timmer, Marco; Sierralta Jara, Jimena; Pietrini, Grazia; Gundelfinger, Eckart D.; Knust, Elisabeth; Thomas, Ulrich (COMPANY OF BIOLOGISTS LTD, 2004-04-15)Stardust (Sdt) and Discs-Large (Dig) are membrane-associated guanylate kinases (MAGUKs) involved in the organization of supramolecular protein complexes at distinct epithelial membrane compartments in Drosophila. Loss of ...
-
Inzunza Melo, Gabriela Alejandra (Universidad de Chile, 2010)La correcta ubicación de todos los componentes sinápticos durante el desarrollo requiere del ordenamiento preciso de una red de proteínas, este ordenamiento es provisto por proteínas andamio, pertenecientes a la familia ...
-
De Gregorio, Cristián; Delgado Arriagada, Ricardo; Ibacache, Andrés; Sierralta Jara, Jimena; Couve Correa, Andrés (Company of Biologists Ltd., 2017)Hereditary spastic paraplegias (HSPs) are characterized by spasticity and weakness of the lower limbs, resulting from length-dependent axonopathy of the corticospinal tracts. In humans, the HSP-related atlastin genes ...
-
Pérez, Francisco R.; Venegas, Fabiola; González, Magdalena; Andrés, Sergio; Vallejos, Catalina; Riquelme Pino, Gloria; Sierralta Jara, Jimena; Michea Acevedo, Luis (American Heart Association, 2009)Recent studies have shown that the epithelial sodium channel (ENaC) is expressed in vascular tissue. However, the role that ENaC may play in the responses to vasoconstrictors and NO production has yet to be addressed. In ...
-
Barros, L. Felipe; Sierralta Jara, Jimena; Weber, Bruno (Elsevier, 2015)Brain energy metabolism powers information processing and behavior, much as electricity powers a computer. However, a recent study in insects suggests that this relationship is more interesting, causally linking ...
-
Majoo Morgado, Pablo Andrés (Universidad de ChilePrograma Cybertesis, 2008)
-
Barría Maturana, Romina (Universidad de Chile, 2006)La localización precisa de los componentes sinápticos durante el desarrollo requiere del ordenamiento de una red de proteínas entre las cuales participan proteínas andamio de la familia MAGUK (membrane-associated guanylate ...
-
Sierralta Jara, Jimena; Mendoza, Carolina (ELSEVIER, 2004-12)Scaffold proteins allow specific protein complexes to be assembled in particular regions of the cell at which they organize subcellular structures and signal transduction complexes. This characteristic is especially important ...
-
Oliva, Carlos; Escobedo, Pía; Astorga, César; Molina, Claudia; Sierralta Jara, Jimena (WILEY-BLACKWELL, 2012-01)Synaptic function is crucially dependent on the spatial organization of the presynaptic and postsynaptic apparatuses and the juxtaposition of both membrane compartments. This precise arrangement is achieved by a protein ...
-
Cánovas, José; Berndt, F. Andrés; Sepúlveda, Hugo; Aguilar, Rodrigo; Veloso, Felipe A.; Montecino, Martín; Oliva, Carlos; Maass Oñate, Juan; Sierralta Jara, Jimena; Kukuljan Padilla, Manuel (Soc. Neuroscience, 2015)The acquisition of distinct neuronal fates is fundamental for the function of the cerebral cortex. We find that the development of subcerebral projections from layer 5 neurons in the mouse neocortex depends on the high ...
-
Albornoz, Valeria; Mendoza-Topaz, Carolina; Oliva, Carlos; Tello, Judith; Olguín Aguilera, Patricio; Sierralta Jara, Jimena (ELSEVIER, 2008-07)The products of the Drosophila discs-large (dlg) gene are members of the MAGUK family of proteins, a group of proteins involved in localization, transport and recycling Of receptors and channels in cell junctions, including ...