Browsing by Author "201-0126548"

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Artículo

alpha 4 beta 2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, ...

Moroni, Mirko; Zwart, Ruud; Sher, Emanuele; Cassels Niven, Bruce; Bermúdez, Isabel (AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2006-08)

Alpha 4 and beta 2 nicotinic acetylcholine receptor ( nAChR) subunits expressed heterologously assemble into receptors with high (HS) and low (LS) sensitivity to acetylcholine (ACh); their relative proportions depend on ...
Artículo

Effects of 9,10-dihydroxy-4,4-dimethyl-5,8-dihydro-1(4H)-anthracenone derivatives on tumor cell respiration

Araya Maturana, Ramiro; Cardona, Wilson; Cassels Niven, Bruce; Delgado Castro, Tomás; Ferrada Parker, Jorge; Miranda, Dante; Pavani, Mario; Pessoa Mahana, Hernán; Soto Delgado, Jorge; Weiss López, Boris (Elsevier Ltd., 2006-02-28)

Abstract—A series of tricyclic hydroquinones, incorporating a carbonyl group in the ortho position relative to the phenol function, were tested as inhibitors of oxygen uptake against the TA3 mouse carcinoma cell line and ...
Artículo

Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human ...

Moya, Pablo R.; Berg, Kelly A.; Gutiérrez Hernández, Manuel A.; Sáez Briones, Patricio; Reyes Parada, Miguel; Cassels Niven, Bruce; Clarke, William P. (2007)

2,5-Dimethoxy-4-substituted phenylisopropylamines and phenethylamines are 5-hydroxytryptamine (serotonin) (5-HT)(2A/2C) agonists. The former are partial to full agonists, whereas the latter are partial to weak agonists. ...