Browsing by Author "201-0262328"
Now showing items 1-3 of 3
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Sapag Muñoz de la Peña, Amalia; Salinas Luypaert, Catalina; Constenla Muñoz, Carlos (Sociedad de Biología de Chile, 2014)Background: Loxoscelism is the envenomation caused by the bite of Loxosceles spp. spiders. It entails severe necrotizing skin lesions, sometimes accompanied by systemic reactions and even death. There are no diagnostic means ...
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Hairpin Ribozyme Genes Curtail Alcohol Drinking: from Rational Design to in vivo Effects in the Rat Sapag Muñoz de la Peña, Amalia; Irarrázaval Aguilera, Thergiorg; Lobos González, Lorena; Muñoz Brauning, Carlos; Quintanilla González, María Elena; Tampier de Jong, Lutske (Nature Publishing Group, 2016)Ribozyme genes were designed to reduce voluntary alcohol drinking in a rat model of alcohol dependence. Acetaldehyde generated from alcohol in the liver is metabolized by the mitochondrial aldehyde dehydrogenase (ALDH2) ...
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Salinas Luypaert, Catalina Francisca (Universidad de Chile, 2013)