Browsing by Author "201-0369899"

Now showing items 21-38 of 38

    • Human papillomavirus 16 E7 promotes EGFR/PI3K/AKT1/NRF2 signaling pathway contributing to PIR/NF-kappa B ... 
      Carrillo Beltrán, Diego; Muñoz, Juan P.; Guerrero Vásquez, Nahir; Blanco, Rancés; León, Oscár; de Souza Lino, Vanesca; Tapia Pineda, Julio; Maldonado Maldonado, Edio; Dubois Camacho, Karen; Hermoso Ramello, Marcela; Coravlán, Alejandro H.; Calaf, Gloria M.; Boccardo, Enrique; Aguayo González, Francisco (MDPI, 2020)
      A subset of oral carcinomas is etiologically related to high-risk human papillomavirus (HR-HPV) infection, with HPV16 being the most frequent HR-HPV type found in these carcinomas. The oncogenic role of HR-HPV is strongly ...
    • The IL-33/ST2 axis: Role in health and disease 
      Fuente, Marjorie de la; MacDonald, Thomas T.; Hermoso Ramello, Marcela (Elsevier, 2015)
      IL-33, an IL-1 family member, is expressed by many cell types and can regulate gene transcription. IL-33 is released upon cell necrosis and the precursor form is enzymatically processed, and then drives inflammation as a ...
    • Inflammatory bowel diseases: An immunological approach Enfermedad inflamatoria intestinal: Una mirada inmunológica 
      Sepúlveda, Sofía E.; Beltrán, Caroll J.; Peralta, Alexis; Rivas, Paola; Rojas, Néstor; Figueroa, Carolina; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2008)
      Inflammatory bowel diseases (IBD) are inflammatory diseases with a multifactorial component that involve the intestinal tract. The two relevant IBD syndromes are Crohn's disease (CD) and ulcerative colitis (UC). One factor ...
    • MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome 
      Sung Hsieh, Hsiao; Castro, I.; González, S.; Aguilera, S.; Smorodinsky, N. I.; Quest, Andrew F. G.; Bahamondes Lorca, Verónica; Alliende, Cecilia; Cortés, J.; Molina, Claudio; Urzúa Tobar, Ulises; Barrera, María José; Hermoso Ramello, Marcela; Herrera Cisterna, Luisa; Leyton Martínez, Cecilia; González Burgos, María Julieta (Wiley-Blackwell, 2015)
      OBJECTIVES: To evaluate the expression and localization of MUC1/SEC and MUC1/Y isoforms in labial salivary glands (LSG) from Sj€ogren’s syndrome patients (SS patients), as well as their in vitro expression induced by ...
    • NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease 
      Figueroa, Carolina; Peralta, Alexis; Herrera Cisterna, Luisa; Castro, Pedro; Gutiérrez, Andrea; Valenzuela Escobar, Jorge; Aguillón Gutiérrez, Juan Carlos; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (JOHN LIBBEY EUROTEXT LTD, 2006-06)
      Crohn's disease (CD) and ulcerative colitis (UC) are multifactorial diseases with a genetic background. Genes related to the innate immune response have been observed to be involved. Polymorphisms of Toll-like receptor 4 ...
    • Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis 
      Beltrán, Caroll J.; Candia, Enzo; Erranz, Benjamín; Figueroa, Carolina; Gonzalez, Maria J.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2009)
      Crohn's disease (CD) and ulcerative colitis (UC) belong to the group of inflammatory bowel diseases (IBD), with complex ethiopathogenic factors that include an unbalanced immune and inflammatory response to commensal and ...
    • Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis (European ... 
      Beltrán, Caroll J.; Candia, Enzo; Erranz, Benjamín; Figueroa, Carolina; Gonzalez, Maria J.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2009)
    • Phosphatidylinositol 3-kinase interacts with the glucocorticoid receptor upon TLR2 activation 
      Arancibia, Sergio; Benítez, Dixán; Núñez, Lucia E.; Jewell, Christine M.; Langjahr, Patricia; Candia, Enzo; Zapata Torres, Gerald; Cidlowski, John A.; González Burgos, María Julieta; Hermoso Ramello, Marcela (2011)
      Airway inflammation is a common condition where glucocorticoids (GC) are a well-established therapy. It has been demonstrated that GC stimulate components of innate immunity. Specifically, GC up-regulate TLR2 expression ...
    • Regulación de la Expresión del Receptor Tipo Toll 4 (TLR4) por el Factor de Necrosis Tumoral α y Glucocorticoides 
      Pérez Núñez, Ramón Daniel (Universidad de ChilePrograma Cybertesis, 2008)
      Durante la inflamación de las mucosas, las células epiteliales y los macrófagos expresan el receptor de tipo Toll 4 (TLR4) y secretan citoquinas, las que potencian el cuadro. Sin embargo, hasta ahora existe escasa información ...
    • Regulación de moléculas de la inmunidad innata por glucocorticoides : papel de la fosfoinositol 3-quinasa ... 
      Arancibia Zunino, Sergio Andrés (Universidad de Chile, 2006)
      Los receptores tipo Toll (TLR) son proteínas de transmembrana que reconocen patrones moleculares asociados a patógenos (PAMPs). El TLR2 reconoce PAMPs de bacterias gram positivas, los cuales activan una vía de señalización ...
    • Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate ... 
      Benitez, Dixan A.; Hermoso Ramello, Marcela; Pozo-Guisado, Eulalia; Fernández-Salguero, Pedro M.; Castellón, Enrique A. (2009)
      BACKGROUND. Polyphenols have been proposed as antitumoral agents. We have shown that resveratrol (RES) induced cell cycle arrest and promoted apoptosis in prostate cancer cells by inhibition of the PI3K pathway. The RES ...
    • RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity 
      Valiente Echeverría, Fernando; Hermoso Ramello, Marcela; Soto Rifo, Ricardo (Wiley-Blackwell, 2015)
      Asp-Glu-Ala-Asp (DEAD)-box polypeptide 3, or DDX3, belongs to the DEAD-box family of ATP-dependent RNA helicases and is known to play different roles in RNA metabolism ranging from transcription to nuclear export, ...
    • Role of CC chemokines subfamily in the platinum drugs resistance promotion in cancer 
      Reyes, María E.; Fuente López, Marjorie de la; Hermoso Ramello, Marcela; Ili, Carmen G.; Brebi, Priscilla (Frontiers Media, 2020)
      Cancer is a significant medical issue, being one of the main causes of mortality around the world. The therapies for this pathology depend on the stage in which the cancer is found, but it is usually diagnosed at an advanced ...
    • Severe alterations in expression and localisation of α6β4 integrin in salivary gland acini from patients ... 
      Velozo, J.; Aguilera, S.; Alliende, C.; Ewert, P.; Molina, C.; Pérez, P.; Leyton, L.; Quest, Andrew F. G.; Brito, M.; González, S.; Leyton, C.; Hermoso Ramello, Marcela; Romo, R.; González, M. J. (2009)
      Objectives: In salivary glands from patients with Sjögren syndrome, overexpression of laminins 1 and 5 and disorganisation of the acinar basal lamina have been reported. Laminin 5 mediates association of the basal lamina ...
    • Sjögren’s syndrome and the epithelial target: A comprehensive review 
      Barrera, M. J.; Bahamondes Cornejo, Valeria Cristina; Sepúlveda, D.; Quest, Andrew F. G.; Castro, I.; Cortés, J.; Aguilera, S.; Urzúa Tobar, Ulises; Molina, C.; Pérez, P.; Ewert, P.; Alliende, C.; Hermoso Ramello, Marcela; González, S.; Leyton Blanca, Cristina; González, M. J. (Elsevier, 2013)
      The most difficult component in our understanding of human autoimmunity remains a rigorous dissection of etiological events. Indeed, the vast literature on autoimmune diseases focuses on the inflammatory response, with ...
    • Soluble ST2 is a sensitive clinical marker of ulcerative colitis evolution 
      Díaz Jiménez, David; De la Fuente, Marjorie; Dubois Camacho, Karen; Landskron, Glauben; Fuentes, Janitza; Pérez, Tamara; González Burgos, María Julieta; Simian, Daniela; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2016)
      Background: The ST2/IL-33 pathway has been related to ulcerative colitis (UC), and soluble ST2 (sST2), to disease severity. We tested the potential usefulness of sST2 as a predictive marker of treatment response and patients' ...
    • Soluble ST2: A new and promising activity marker in ulcerative colitis 
      Díaz Jiménez, David; Núñez, Lucía E.; Beltrán, Caroll J.; Candia, Enzo; Suazo, Cristóbal; Álvarez Lobos, Manuel; González Burgos, María Julieta; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2011)
      AIM: To correlate circulating soluble ST2 (sST2) levels with the severity of ulcerative colitis (UC) and serum levels of pro-inflammatory cytokines, and to demonstrate the predictive power of sST2 levels for differentiation ...
    • Toll-like receptors are key participants in innate immune responses 
      Arancibia, Sergio A.; Beltrán, Caroll J.; Aguirre, Isabel M.; Silva, Paulina; Peralta, Alexis L.; Malinarich, Frano; Hermoso Ramello, Marcela (Society of Biology of Chile, 2007)
      During an infection, one of the principal challenges for the host is to detect the pathogen and activate a rapid defensive response. The Toll-like family of receptors (TLRs), among other pattern recognition receptors (PRR), ...