Browsing by Author "201-0369899"

Now showing items 1-20 of 38

    • 17-beta-Estradiol upregulates COX-2 in the rat oviduct 
      Pérez Martínez, S.; Hermoso Ramello, Marcela; Farina, M.; Ribeiro, M. L.; Rapanelli, M.; Espinosa, M.; Villalón Calderón, Marcelo; Franchi, A. (ELSEVIER, 2006-09)
      We investigated the regulation of cyclooxygenase-2 (COX-2) by 17-beta-estradiol (E-2) in the rat oviduct. We observed that COX-2 is expressed mainly in proestrous and estrous stages, periods under estrogenic influence. ...
    • A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis 
      Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)
      The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
    • An update on the pathogenesis of celiac disease Enfermedad celíaca y su patogenia 
      Herrera, María José; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2009)
      Celiac disease (CD), with a 1% world-wide prevalence, is an enteropathy caused by an autoimmune reaction to gluten in genetically susceptible individuals, that codify for histocompatibility molecules HLA DQ-2/DQ-8. From ...
    • Análisis de polimorfismos genéticos del gen NOD2/CARD 15 y TLR4, asociados a enfermedades Inflamatorias ... 
      Peralta Bondi, Alexis Luis (Universidad de ChilePrograma Cybertesis, 2007)
      La Enfermedad de Crohn (EC) y la Colitis Ulcerosa (CU) enfermedades inflamatorias intestinales (EII) multifactoriales que presentan una relación genética importante. Recientemente se han descrito polimorfismos en los ...
    • Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and ... 
      Lagos, Carolina; Carvajal, Patricia; Castro, Isabel; Jara, Daniela; González, Sergio; Aguilera, Sergio; Barrera, María José; Quest, Andrew F. G.; Bahamondes, Verónica; Molina, Claudio; Urzúa, Ulises; Hermoso Ramello, Marcela; Leyton, Cecilia; González Burgos, María Julieta (Academic Press Inc., 2018)
      © 2018 Elsevier Inc.Here, we determined the 5-hydroxymethylcytosine (5hmC), 5-methylcytosine (5mC), Ten Eleven Translocation (TETs), and DNA methyltransferases (DNMTs) levels in epithelial and inflammatory cells of labial ...
    • Células T γδ intraepiteliales intestinales y su influencia en la homeostasis intestinal: Estudio de la ... 
      Malinarich González, Frano Hernán (Universidad de ChileCyberDocs, 2010)
    • Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease 
      Beltrán, Caroll J.; Núñez, Lucía E.; Díaz Jiménez, David; Farfán, Nancy; Candia, Enzo; Heine, Claudio; López, Francisco; González Burgos, María Julieta; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2010)
      Background: ST2 has been proposed to be a regulator of inflammation and Th1/Th2 balance. ST2L is the IL-33 membrane receptor and belongs to the IL-1R family. The soluble variant, ST2s, is identical to the extracellular ...
    • Chronic inflammation and cytokines in the tumor microenvironment 
      Landskron, Glauben; Fuente, Marjorie de la; Thuwajit, Peti; Thuwajit, Chanitra; Hermoso Ramello, Marcela (Hindawi Publishing, 2014)
      Acute inflammation is a response to an alteration induced by a pathogen or a physical or chemical insult, which functions to eliminate the source of the damage and restore homeostasis to the affected tissue. However, ...
    • Crohn associated microbial communities associated to colonicmucosal biopsies in patients of the western ... 
      Vidal Álvarez, Roberto; Ginardb, Daniel; Khorramib, Sam; Mora Ruiz, Merit; Muñoz, Raúl; Hermoso Ramello, Marcela; Díaz, Sara; Cifuentes, Ana; Orfila, Alejandro; Rosselló Mora, Ramón (Elsevier, 2015)
      Next generation sequencing approaches allow the retrieval of several orders of magnitude larger numbers of amplified single sequences in 16S rRNA diversity surveys than classical methods. However, the sequences are only ...
    • Efecto de un lipopeptido bacteriano y glucocorticoide en células de inmunidad innata: rol de p38 
      Valenzuela Díaz, Rodrigo Hernán (Universidad de ChilePrograma Cybertesis, 2008)
      Como parte del sistema inmune innato existe un grupo de receptores de reconocimiento de patrones (PRRs) capaces de detectar aquellos patrones moleculares asociados a patógenos (PAMPs). Entre estos PRRs, destacan los ...
    • Effect of oestradiol and progesterone on the instant and directional velocity of microsphere movements in ... 
      Ríos, Mariana; Hermoso Ramello, Marcela; Sánchez, Trinidad M.; Croxatto, Horacio B.; Villalón, Manuel J. (2007)
      The oviducal transport of eggs to the uterus normally takes 72 - 96 h in the rat, but this is reduced to less than 20 h after a single injection of oestradiol ( E2). This accelerated transport is associated with an increased ...
    • Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived ... 
      Flores, Karen A.; Salgado, J. Cristian; Zapata Torres, Gerald; Gerdtzen Hakim, Ziomara; Gonzalez, María Julieta; Hermoso Ramello, Marcela (2012)
      In order to develop future therapeutic applications for cell penetrating peptides (CPPs), it is essential to characterize their internalization mechanisms, as they might affect the stability and the accessibility of the ...
    • Enfermedad inflamatoria intestinal: Una mirada inmunológica 
      Sepúlveda, Sofía E.; Beltrán Muñoz, Caroll; Peralta, Alexis; Rivas, Paola; Rojas, Néstor; Figueroa, Carolina; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (SOC MEDICA SANTIAGO, 2008-03)
      Inflammatory bowel diseases (IBD) are inflammatory diseases with a multifactorial component that involve the intestinal tract. The two relevant IBD syndromes are Crohn’s disease (CD) and ulcerative colitis (UC). One ...
    • Escherichia coli isolates from inflammatory bowel diseases patientssurvive in macrophages and activate NLRP3 ... 
      Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriela; Vidal Álvarez, Roberto; Hermoso Ramello, Marcela (Elsevier, 2014)
      Crohn’s disease (CD) is a multifactorial pathology associated with the presence of adherent-invasiveEscherichia coli (AIEC) and NLRP3 polymorphic variants. The presence of intracellular E. coli in otherintestinal pathologies ...
    • Estudio del Mecanismo de Internalización de los Péptidos de Penetración Celular TIRAP y TIRAPALA en Células HeLa 
      Flores Olave, Karen Alejandra (Universidad de ChileCyberDocs, 2010)
      Los Péptidos de Penetración Celular (o CPPs) poseen la habilidad de transportar moléculas a través de la membrana plasmática, sin pérdida de su integridad. Entre las secuencias más estudiadas se encuentran TAT, Antennapedia ...
    • Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: ... 
      Boza Fuentes, Pía; Ayala, Pedro; Vivar Sánchez, Raúl; Humeres Martínez, Claudio; Tapia Cáceres, Felipe; Muñoz, Claudia; García Nannig, Lorena; Hermoso Ramello, Marcela; Díaz Araya, Guillermo (Elsevier, 2016)
      Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead cells after cardiac ...
    • Gene expression and chromosomal location for susceptibility to Sjögren's syndrome 
      Pérez, Paola; Anaya, Juan Manuel; Aguilera, Sergio; Urzúa Tobar, Ulises; Munroe, David; Molina, Claudio; Hermoso Ramello, Marcela; Cherry, James Michael; Alliende, Cecilia; Olea, Nancy; Ruiz-Narváez, Edward; González Burgos, María Julieta (2009)
      Primary Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease affecting mainly the exocrine glands. Its physio-pathology is poorly understood and most of the knowledge has been related to the inflammatory ...
    • Glucocorticosteroid therapy in inflammatory bowel diseases: from clinical practice to molecular biology 
      Dubois Camacho, Karen; Ottum, Payton A.; Franco Muñoz, Daniel; Fuente, Marjorie de la; Torres Riquelme, Alejandro; Díaz Jiménez, David; Olivares Morales, Mauricio; Astudillo, Gonzalo; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Baishideng Publishing Group, 2017)
      Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are chronic pathologies associated with a deregulated immune response in the intestinal mucosa, and they are triggered by environmental ...
    • Heat-Shock Induction of Tumor-Derived Danger Signals Mediates Rapid Monocyte Differentiation into Clinically ... 
      Aguilera, Raquel; Saffie, Carlos; Tittarelli, Andrés; González Bergas, Fermín; Ramírez Fernández, Marcos; Reyes, Diego; Pereda, Cristián; Hevia, Daniel; García, Tamara; Salazar, Lorena; Ferreira Vigouroux, Luis Arturo; Hermoso Ramello, Marcela; Mendoza Naranjo, Ariadna; Ferrada, Carlos; Garrido, Paola; López Nitsche, Mercedes; Salazar Onfray, Flavio (AMER ASSOC CANCER RESEARCH, 2011-04-15)
      Purpose: This study characterizes, biologically and clinically, a novel type of dendritic cells (DC) produced in the short term and called tumor antigen–presenting cells (TAPCells). In particular, we identified factors ...
    • High level of interleukin-33 in cancer cells and cancer-associated fibroblasts correlates with good prognosis ... 
      Yangngam, Supaporn; Thongchot, Suyanee; Pongpaibul, Ananya; Vaeteewoottacharn, Kulthida; Pinlaor, Somchai; Thuwajit, Peti; Okada, Seiji; Hermoso Ramello, Marcela; Thuwajit, Chanitra (Ivyspring International Publisher, 2020)
      Interleukin 33 (IL-33) promotes cholangiocarcinoma (CCA) genesis in a mouse model, however, its function in human CCA has not been clearly understood. This study was aimed to investigate IL-33 level in CCA tissues and its ...