Now showing items 1-20 of 42

    • Pérez Martínez, S.; Hermoso Ramello, Marcela; Farina, M.; Ribeiro, M. L.; Rapanelli, M.; Espinosa, M.; Villalón Calderón, Marcelo; Franchi, A. (ELSEVIER, 2006-09)
      We investigated the regulation of cyclooxygenase-2 (COX-2) by 17-beta-estradiol (E-2) in the rat oviduct. We observed that COX-2 is expressed mainly in proestrous and estrous stages, periods under estrogenic influence. ...
    • Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)
      The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
    • Herrera, María José; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2009)
      Celiac disease (CD), with a 1% world-wide prevalence, is an enteropathy caused by an autoimmune reaction to gluten in genetically susceptible individuals, that codify for histocompatibility molecules HLA DQ-2/DQ-8. From ...
    • Peralta Bondi, Alexis Luis (Universidad de ChilePrograma Cybertesis, 2007)
      La Enfermedad de Crohn (EC) y la Colitis Ulcerosa (CU) enfermedades inflamatorias intestinales (EII) multifactoriales que presentan una relación genética importante. Recientemente se han descrito polimorfismos en los ...
    • Lagos, Carolina; Carvajal, Patricia; Castro, Isabel; Jara, Daniela; González, Sergio; Aguilera, Sergio; Barrera, María José; Quest, Andrew F. G.; Bahamondes, Verónica; Molina, Claudio; Urzúa, Ulises; Hermoso Ramello, Marcela; Leyton, Cecilia; González Burgos, María Julieta (Academic Press Inc., 2018)
      © 2018 Elsevier Inc.Here, we determined the 5-hydroxymethylcytosine (5hmC), 5-methylcytosine (5mC), Ten Eleven Translocation (TETs), and DNA methyltransferases (DNMTs) levels in epithelial and inflammatory cells of labial ...
    • Malinarich González, Frano Hernán (Universidad de ChileCyberDocs, 2010)
    • Beltrán, Caroll J.; Núñez, Lucía E.; Díaz Jiménez, David; Farfán, Nancy; Candia, Enzo; Heine, Claudio; López, Francisco; González Burgos, María Julieta; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (2010)
      Background: ST2 has been proposed to be a regulator of inflammation and Th1/Th2 balance. ST2L is the IL-33 membrane receptor and belongs to the IL-1R family. The soluble variant, ST2s, is identical to the extracellular ...
    • Landskron, Glauben; Fuente, Marjorie de la; Thuwajit, Peti; Thuwajit, Chanitra; Hermoso Ramello, Marcela (Hindawi Publishing, 2014)
      Acute inflammation is a response to an alteration induced by a pathogen or a physical or chemical insult, which functions to eliminate the source of the damage and restore homeostasis to the affected tissue. However, ...
    • Vidal Álvarez, Roberto; Ginardb, Daniel; Khorramib, Sam; Mora Ruiz, Merit; Muñoz, Raúl; Hermoso Ramello, Marcela; Díaz, Sara; Cifuentes, Ana; Orfila, Alejandro; Rosselló Mora, Ramón (Elsevier, 2015)
      Next generation sequencing approaches allow the retrieval of several orders of magnitude larger numbers of amplified single sequences in 16S rRNA diversity surveys than classical methods. However, the sequences are only ...
    • Valenzuela Díaz, Rodrigo Hernán (Universidad de ChilePrograma Cybertesis, 2008)
      Como parte del sistema inmune innato existe un grupo de receptores de reconocimiento de patrones (PRRs) capaces de detectar aquellos patrones moleculares asociados a patógenos (PAMPs). Entre estos PRRs, destacan los ...
    • Ríos, Mariana; Hermoso Ramello, Marcela; Sánchez, Trinidad M.; Croxatto, Horacio B.; Villalón, Manuel J. (2007)
      The oviducal transport of eggs to the uterus normally takes 72 - 96 h in the rat, but this is reduced to less than 20 h after a single injection of oestradiol ( E2). This accelerated transport is associated with an increased ...
    • Flores, Karen A.; Salgado, J. Cristian; Zapata Torres, Gerald; Gerdtzen Hakim, Ziomara; Gonzalez, María Julieta; Hermoso Ramello, Marcela (2012)
      In order to develop future therapeutic applications for cell penetrating peptides (CPPs), it is essential to characterize their internalization mechanisms, as they might affect the stability and the accessibility of the ...
    • Sepúlveda, Sofía E.; Beltrán Muñoz, Caroll; Peralta, Alexis; Rivas, Paola; Rojas, Néstor; Figueroa, Carolina; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (SOC MEDICA SANTIAGO, 2008-03)
      Inflammatory bowel diseases (IBD) are inflammatory diseases with a multifactorial component that involve the intestinal tract. The two relevant IBD syndromes are Crohn’s disease (CD) and ulcerative colitis (UC). One ...
    • Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriela; Vidal Álvarez, Roberto; Hermoso Ramello, Marcela (Elsevier, 2014)
      Crohn’s disease (CD) is a multifactorial pathology associated with the presence of adherent-invasiveEscherichia coli (AIEC) and NLRP3 polymorphic variants. The presence of intracellular E. coli in otherintestinal pathologies ...
    • Flores Olave, Karen Alejandra (Universidad de ChileCyberDocs, 2010)
      Los Péptidos de Penetración Celular (o CPPs) poseen la habilidad de transportar moléculas a través de la membrana plasmática, sin pérdida de su integridad. Entre las secuencias más estudiadas se encuentran TAT, Antennapedia ...
    • Boza Fuentes, Pía; Ayala, Pedro; Vivar Sánchez, Raúl; Humeres Martínez, Claudio; Tapia Cáceres, Felipe; Muñoz, Claudia; García Nannig, Lorena; Hermoso Ramello, Marcela; Díaz Araya, Guillermo (Elsevier, 2016)
      Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead cells after cardiac ...
    • Pérez, Paola; Anaya, Juan Manuel; Aguilera, Sergio; Urzúa Tobar, Ulises; Munroe, David; Molina, Claudio; Hermoso Ramello, Marcela; Cherry, James Michael; Alliende, Cecilia; Olea, Nancy; Ruiz-Narváez, Edward; González Burgos, María Julieta (2009)
      Primary Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease affecting mainly the exocrine glands. Its physio-pathology is poorly understood and most of the knowledge has been related to the inflammatory ...
    • Céspedes, Sandra; Saitz Rojas, Waleska; Canto Fuentes, Felipe del; Fuente, Marjorie de la; Quera Pino, Rodrigo; Hermoso Ramello, Marcela; Muñoz, Raúl; Ginard, Daniel; Khorrami, Sam; Jorge, Girón; Assar Cuevas, Rodrigo; Rosello Mora, Ramón; Vidal Álvarez, Roberto (Frontiers Media, 2017-05-24)
      Adherent-invasive Escherichia coli (AIEC) strains are genetically variable and virulence factors for AIEC are non-specific. FimH is the most studied pathogenicity-related protein, and there have been few studies on other ...
    • Olivares Morales, Mauricio; De la Fuente, Marjorie; Dubois Camacho, Karen; Palominos Parada, Daniela Paz; Díaz Jiménez, David; Torres Riquelme, Alejandro; Xu, Xiaojiang; Chamorro Veloso, Nayaret; Naves, Rodrigo; González Burgos, María Julieta; Quera Pino, Rodrigo; Figueroa, Carolina; Cidlowski, John Anthony; Vidal, Roberto; Hermoso Ramello, Marcela (Frontiers Media, 2018-05-16)
      Crohn's disease (CD) is a chronic inflammatory bowel disorder characterized by deregulated inflammation triggered by environmental factors Notably, adherent-invasive Escherichia coli (AIEC), a bacterium with the ability ...
    • Dubois Camacho, Karen; Ottum, Payton A.; Franco Muñoz, Daniel; Fuente, Marjorie de la; Torres Riquelme, Alejandro; Díaz Jiménez, David; Olivares Morales, Mauricio; Astudillo, Gonzalo; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Baishideng Publishing Group, 2017)
      Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are chronic pathologies associated with a deregulated immune response in the intestinal mucosa, and they are triggered by environmental ...