The effects of intracoerulear CRH and intraparaventricular prazosin on systolic pressure, diastolic pressure and heart rate were studied in prenatally malnourished hypertensive rats. At day 40 of life, (i) malnourished ...

Rats submitted to fetal growth retardation by in utero malnutrition develop hypertension when adult, showing increased hypothalamic mRNA expression for corticotropin-releasing hormone (CRH) and increased central noradrenergic ...

Prenatal undernutrition is known to disturb the hypothalamo-pituitary-adrenal (HPA) axis, possibly through the programming of decreased expression of hypothalamic and pituitary glucocorticoid receptors. To test this ...