Browsing by Author "201-0432927"
Now showing items 1-20 of 46
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Mani, S. K.; Lara, H.; Romero Osses, Carmen; Handa, R. J.; Wu, T. J. (2012)
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Oróstica Arévalo, María Lorena; Rosas Chuñil, Carlos; Plaza Parrochia, Francisca; Astorga Leiva, Isis; Gabler Neale, Fernando; García Angulo, Víctor; Romero Osses, Carmen; Vega Blanco, María Margarita (Bentham Science, 2016)Background: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine/metabolic disorder characterized by hyperandrogenemia and in most cases, by hyper-insulinemia in addition to obesity. Besides ovarian dysfunction, ...
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Araya Quintanilla, Aída Verónica; Romero Osses, Carmen; Lemp Miranda, Melchor (Springer, 2017)
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Muñoz Carvacho, Marcela Francisca (Universidad de ChileCyberDocs, 2008)El cáncer ovárico representa la segunda causa de muerte de origen ginecológico, y el 80-90% corresponde a carcinoma ovárico epitelial (COE), del cual el 40% es de tipo seroso. Esta patología se caracteriza por presentar ...
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Valladares, Macarena; Plaza Parrochia, Francisca; Lepez, Macarena; López Ponce, Daniela; Gabler Neale, Fernando; Gayan, Patricio; Selman, Alberto; Vega Blanco, María Margarita; Romero Osses, Carmen (Francisco Hernández, Editor, 2017)Introduction: Ovarian cancer presents a high angiogenesis (formation of new blood vessels) regulated by pro-angiogenic factors, mainly vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). An association ...
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Julio Pieper, Marcela; Lara Peñaloza, Hernán; Bravo, Javier A.; Romero Osses, Carmen (2006)Background: Angiogenesis is a crucial process in follicular development and luteogenesis. The nerve growth factor (NGF) promotes angiogenesis in various tissues. An impaired production of this neurotrophin has been associated ...
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Plaza Parrochia, Francisca; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2017)Normal endometrial function requires of cell proliferation and differentiation; therefore, disturbances in these processes could lead to pathological entities such as hyperplasia and endometrial adenocarcinoma, where cell ...
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Ormazábal, Paulina; Romero Osses, Carmen; Gabler Neale, Fernando; Quest, Andrew F. G.; Vega Blanco, María Margarita (2013)
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Paredes, Alfonso; Romero Osses, Carmen; Dissen, Gregory A.; DeChiara, Tom M.; Reichardt, Louis; Cornea, Anda; Ojeda, Sergio R.; Xu, Baoji (Academic Press Inc., 2004)
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Araya, A. Veronica; Aguirre, Adam; Romero Osses, Carmen; Bersezio Miranda, Cristian; Molina, Maria Carmen; Ferreira, Arturo (2002)In mammals, the pleiotropic biological functions of tumor necrosis factor alpha (TNF-α) may include important effects on human reproductive physiology. Thus, chronic anovulation, oligo or amenorrhea, infertility, ...
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Vera Castillo, Carolina Andrea (Universidad de ChileCyberDocs, 2011)En el cáncer ovárico epitelial (COEI), el ovario pierde el control normal de la angiogénesis. El COE exhibe alta expresión del Factor de Crecimiento Nervioso (NGF), un factor proangiogénico. Por otro lado, la calreticulina ...
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Avellaira, C.; Villavicencio, A.; Bacallao, Ketty; Gabler Neale, Fernando; Wells, P.; Romero Osses, Carmen; Vega Blanco, María Margarita (Oxford University Press, 2006)Background: The hormonal alterations observed in women with polycystic ovary syndrome (PCOS) may promote implantation failure as well as disruption of their endometrial homeostasis. To evaluate cell survival of mid-secretory ...
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Plaza Parrochia, Francisca; Poblete, Cristian; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2015)Intracrinology mechanism involves the metabolism of steroids in peripheral tissues, such as DHEA, to molecules with estrogenic or androgenic activity. Proliferation rate of endometria from Polycystic Ovary Syndrome women ...
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Jara Sosa, Lilian; González Hormazábal, Patricio; Cerceño, Kerube; Di Capua, Gabriella A.; Reyes, José M.; Blanco Castillo, Rafael; Bravo, Teresa; Peralta Musre, Octavio; Gómez, Fernando; Waugh, Enrique; Margarit, Sonia; Gladys, Ibáñez; Romero Osses, Carmen; Pakomio, Janara; Roizen, Gigia (SPRINGER, 2012-12-07)Genome-Wide Association Studies have identified several loci associated with breast cancer (BC) in populations of different ethnic origins. One of the strongest associations was found in the FGFR2 gene, and MAP3K1 has ...
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Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells Rosas Chuñil, Carlos; Oróstica Arévalo, María Lorena; Poblete, Cristian; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Lavandero González, Sergio; Vega Blanco, María Margarita (SAGE, 2016)Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic hyperandrogenemia. Different evidence have shown that androgens could regulate the endoplasmic reticulum (ER) homeostasis and glucose ...
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Lépez Rivera, Macarena Paz (Universidad de Chile, 2009)Introducción: El Cáncer de Ovario Epitelial (COE) es el cáncer ginecológico con mayor mortalidad en mujeres post-menopáusica. Su carcinogénesis y progresión neoplásica es atribuida a múltiples moléculas relacionadas con ...
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Girardi Silva, Silvanna Andrea (Universidad de Chile, 2011)El receptor de alta afinidad de la neurotrofina NGF, TRKA, ha sido asociado con distintos tipos de cáncer, pudiendo encontrarse isoformas de este receptor. En el cáncer ovárico no se han descrito isoformas de este receptor, ...
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Astorga Leiva, Isis Paulina (Universidad de Chile, 2015)El síndrome de ovario poliquístico (SOP) es una patología endocrino metabólica que afecta entre el 5% - 10% de mujeres que se encuentran en período reproductivo. Un número elevado de estas mujeres son infértiles, acentuando ...
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Croxatto, Horacio B.; Salvatierra, Ana Maria; Romero Osses, Carmen; Spitz, Irving M. (1987)RU486, a 19-nor steroid, binds with high affinity to the receptors for progesterone and glucocorticoids, blocking the actions of these hormones on their target tissues. We conducted studies to determine whether RU486 ...
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Bacallao, Ketty; Plaza Parrochia, Francisca; Cerda, A.; Gabler Neale, Fernando; Romero Osses, Carmen; Vantman Bretschneider, David; Vega Blanco, María Margarita (SAGE, 2016)Polycystic ovarian syndrome (PCOS) has been associated with endometrial hyperplasia and cancer. The aim of this study was to establish whether the expression of proliferation regulatory proteins in the endometria of ...